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    <front>
        <journal-meta>
            <journal-id journal-id-type="publisher-id">JMU</journal-id>
            <journal-id journal-id-type="nlm-ta">JMIR mHealth uHealth</journal-id>
            <journal-title>JMIR mHealth and uHealth</journal-title>
            <issn pub-type="epub">2291-5222</issn>
            <publisher>
                <publisher-name>JMIR Publications Inc.</publisher-name>
                <publisher-loc>Toronto, Canada</publisher-loc>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="publisher-id">v3i3e87</article-id>
            <article-id pub-id-type="pmid">26369346</article-id>
            <article-id pub-id-type="doi">10.2196/mhealth.4532</article-id>
            <article-categories>
                <subj-group subj-group-type="heading">
                    <subject>Original Paper</subject>
                </subj-group>
                <subj-group subj-group-type="article-type">
                    <subject>Original Paper</subject>
                </subj-group>
            </article-categories>
            <title-group>
                <article-title>A Framework to Assist Health Professionals in Recommending High-Quality Apps for Supporting Chronic
Disease Self-Management: Illustrative Assessment of Type 2 Diabetes Apps</article-title>
            </title-group>
            <contrib-group>
                <contrib contrib-type="editor">
                    <name>
                        <surname>Eysenbach</surname>
                        <given-names>Gunther</given-names>
                    </name>
                </contrib>
            </contrib-group>
            <contrib-group>
                <contrib contrib-type="reviewer">
                    <name>
                        <surname>Azar</surname>
                        <given-names>Kristen</given-names>
                    </name>
                </contrib>
                <contrib contrib-type="reviewer">
                    <name>
                        <surname>Riley</surname>
                        <given-names>William</given-names>
                    </name>
                </contrib>
                <contrib contrib-type="reviewer">
                    <name>
                        <surname>Mani</surname>
                        <given-names>Madhavan</given-names>
                    </name>
                </contrib>
            </contrib-group>
            <contrib-group>
                <contrib contrib-type="author" id="contrib1" corresp="yes">
                    <name name-style="western">
                        <surname>Hale</surname>
                        <given-names>Kelli</given-names>
                    </name>
                    <degrees>BAppSc, BHlthSc(Nutr&#38;Diet)(Hons)</degrees>
                    <xref rid="aff1" ref-type="aff">1</xref>
                    <address>
                        <institution>Centre of Dietetics Research</institution>
                        <institution>School of Human Movement and Nutrition Sciences</institution>
                        <institution>University of Queensland</institution>
                        <addr-line>Building 26B</addr-line>
                        <addr-line>Cnr Blair &#38; Union Rds</addr-line>
                        <addr-line>St Lucia, 4072</addr-line>
                        <country>Australia</country>
                        <phone>61 7 3346 7703</phone>
                        <fax>61 7 3365 6877</fax>
                        <email>k.hale@uq.edu.au</email>
                    </address>
                    <ext-link ext-link-type="orcid">http://orcid.org/0000-0003-4815-137X</ext-link>
                </contrib>
                <contrib contrib-type="author" id="contrib2">
                    <name name-style="western">
                        <surname>Capra</surname>
                        <given-names>Sandra</given-names>
                    </name>
                    <degrees>DipNutr&#38;Diet, BSc(Hons), MSocSc, PhD, AM</degrees>
                    <xref rid="aff1" ref-type="aff">1</xref>
                    <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-0926-8500</ext-link>
                </contrib>
                <contrib contrib-type="author" id="contrib3">
                    <name name-style="western">
                        <surname>Bauer</surname>
                        <given-names>Judith</given-names>
                    </name>
                    <degrees>GradDipNutr&#38;Diet, BSc, MHlthSc, PhD</degrees>
                    <xref rid="aff1" ref-type="aff">1</xref>
                    <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-3830-5147</ext-link>
                </contrib>
            </contrib-group>
            <aff id="aff1">
                <sup>1</sup>
                <institution>Centre of Dietetics Research</institution>
                <institution>School of Human Movement and Nutrition Sciences</institution>
                <institution>University of Queensland</institution>
                <addr-line>St Lucia</addr-line>
                <country>Australia</country>
            </aff>
            <author-notes>
                <corresp>Corresponding Author: Kelli Hale <email>k.hale@uq.edu.au</email>
                </corresp>
            </author-notes>
            <pub-date pub-type="collection">
                <season>Jul-Sep</season>
                <year>2015</year>
            </pub-date>
            <pub-date pub-type="epub">
                <day>14</day>
                <month>09</month>
                <year>2015</year>
            </pub-date>
            <volume>3</volume>
            <issue>3</issue>
            <elocation-id>e87</elocation-id>
            <!--history from ojs - api-xml-->
            <history>
                <date date-type="received">
                    <day>14</day>
                    <month>4</month>
                    <year>2015</year>
                </date>
                <date date-type="rev-request">
                    <day>7</day>
                    <month>5</month>
                    <year>2015</year>
                </date>
                <date date-type="rev-recd">
                    <day>25</day>
                    <month>5</month>
                    <year>2015</year>
                </date>
                <date date-type="accepted">
                    <day>15</day>
                    <month>8</month>
                    <year>2015</year>
                </date>
            </history>
            <!--(c) the authors - correct author names and publication date here if necessary. Date in form ', dd.mm.yyyy' after jmir.org-->
            <copyright-statement>&#169;Kelli Hale, Sandra Capra, Judith Bauer. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 14.09.2015. </copyright-statement>
            <copyright-year>2015</copyright-year>
            <license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/2.0/">
                <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR mhealth and uhealth, is properly cited. The complete bibliographic information, a link to the original publication on http://mhealth.jmir.org/, as well as this copyright and license information must be included.</p>
            </license>
            <self-uri xlink:href="http://mhealth.jmir.org/2015/3/e87/" xlink:type="simple" />
            <abstract>
                <sec sec-type="background">
                    <title>Background</title>
                    <p>This paper presents an approach to assist health professionals in recommending high quality apps for supporting chronic disease self-management. Most app reviews focus on popularity, aesthetics, functionality, usability, and information quality.  There is no doubt these factors are important in selecting trustworthy apps which are appealing to users, but behavioral theory may be also be useful in matching the apps to user needs.</p>
                </sec>
                <sec sec-type="objective">
                    <title>Objective</title>
                    <p>The framework developed aims to be methodologically sound, capable of selecting popular apps which include content covered by evidence-based programs, consistent with behavioral theory, as well as a patient-centered approach for matching apps to patients&#8217; individual needs.</p>
                </sec>
                <sec sec-type="methods">
                    <title>Methods</title>
                    <p>A single disease&#8212;type 2 diabetes&#8212;was selected to illustrate how the framework can be applied as this was deemed to represent the types of strategies used in many chronic diseases.  A systematic approach based on behavioral theory and recommendations from best practice guidelines was developed for matching apps to patients&#8217; needs.  In March 2014, a series of search strategies was used to identify top-rated iPhone and Android health apps, representing 29 topics from five categories of type 2 diabetes self-management strategies. The topics were chosen from published international guidelines for the management of diabetes.  The senior author (KH) assessed the most popular apps found that addressed these topics using the Behavioral Theory Content Survey (BTS), which is based on traditional behavioral theory. A tool to assist decision making when using apps was developed and trialed with health professionals for ease of use and understanding.</p>
                </sec>
                <sec sec-type="results">
                    <title>Results</title>
                    <p>A total of 14 apps were assessed representing all five topic categories of self-management. Total theoretical scores (BTS scores) were less than 50 on a 100-point scale for all apps. Each app scored less than 50% of the total possible BTS score for all four behavioral theories and for most of the 20 behavioral strategies; however, apps scored higher than 50% of the total possible BTS score for specific strategies related to their primary focus. Our findings suggest that the apps studied would be more effective when used in conjunction with therapy than as stand-alone apps.  Apps were categorized according to topic and core intervention strategies.  A framework for matching apps to identified patient needs was developed based on app categorization and principles of patient-centered care.  The approach was well accepted and understood by a convenience sample of health practitioners.</p>
                </sec>
                <sec sec-type="conclusions">
                    <title>Conclusions</title>
                    <p>The framework presented can be used by health practitioners to better match apps with client needs. Some apps incorporate highly interactive strategies of behavioral theory, and when used as an adjunct may increase patient participation and the effectiveness of therapy.</p>
                </sec>
            </abstract>
            <kwd-group>
                <kwd>mobile apps</kwd>
                <kwd>chronic disease</kwd>
                <kwd>patient-centered care</kwd>
                <kwd>technology</kwd>
            </kwd-group>
        </article-meta>
    </front>
    <body>
        <sec sec-type="introduction">
            <title>Introduction</title>
            <p>Chronic disease is Australia&#8217;s biggest health challenge, accounting for 90% of all deaths in 2011 [<xref ref-type="bibr" rid="ref1">1</xref>]. These diseases are prolonged in duration, do not often resolve spontaneously, and are rarely cured completely [<xref ref-type="bibr" rid="ref1">1</xref>]. They are typically associated with lifestyle choices; therefore, for treatment to be effective, patients need to be willing and able to manage their own condition on a daily basis.</p>
            <p>Self-management is now considered the appropriate strategy for chronic diseases where lifestyle is critical to management. Traditionally, health professionals have delivered chronic disease self-management (CDSM) interventions to individuals in one-on-one or group situations. Studies have found conventional interventions are most effective when delivered using a patient-centered approach, over long periods, with short follow-up, and regular reinforcement [<xref ref-type="bibr" rid="ref2">2</xref>]. Unfortunately, these interventions are expensive to implement and difficult to sustain in the primary care setting. Less intensive interventions are needed, and mobile technologies may be helpful as they are affordable and practical. Furthermore, mobile technologies promote increased patient participation which is an essential component of CDSM.</p>
            <p>Australians own more advanced-feature mobile phones and have downloaded more apps than many other developed countries. In 2013, 64% of the Australian population owned an advance-feature mobile phone and the average user has 33 apps installed [<xref ref-type="bibr" rid="ref3">3</xref>]. App use will increase as it is predicted that 91% of the population will own an advanced-feature mobile phone by 2017 [<xref ref-type="bibr" rid="ref3">3</xref>]. Although app research is limited, many studies have found significant improvements in chronic disease outcomes using mobile interventions [<xref ref-type="bibr" rid="ref4">4</xref>,<xref ref-type="bibr" rid="ref5">5</xref>]. Most of the interventions used simple technologies such as short message service (SMS) text messaging for self-monitoring and automated feedback; mobile apps are more sophisticated with real-time, graphic feedback and social functionality.</p>
            <p>Due to their popularity, portability, connectivity, and increasing sophistication, apps are an ideal platform for influencing behavior. Despite this, users receive little guidance and support in selecting health apps. Health apps do not require approval from the Therapeutic Goods Administration (TGA) or any other body in Australia to our knowledge. There is a general lack of trust among health professionals in the quality of apps, as many are developed by businesses for commercial gain. A small number of professional organizations recommend apps based on the authenticity of content, user engagement, and aesthetics. While there is no doubt these factors are important in selecting trustworthy apps which are appealing to users, they do not define what apps do or how they can be used to assist in changing behavior.</p>
            <p>Current broad international diabetes guidelines recommend interventions be based on behavioral theory [<xref ref-type="bibr" rid="ref6">6</xref>,<xref ref-type="bibr" rid="ref7">7</xref>,<xref ref-type="bibr" rid="ref8">8</xref>]. Behaviorally focused interventions that include interactive strategies have the greatest impact on metabolic and diabetes self-care outcomes [<xref ref-type="bibr" rid="ref9">9</xref>]. Furthermore, behavioral theories provide a systematic way of explaining and predicting behavior. Social cognitive models have been used as a framework for assessing the behavioral theory content of lifestyle interventions [<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref11">11</xref>]. The Behavioral Theory Content Survey (BTS) is a validated tool [<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref12">12</xref>] which has been shown to have substantial interrater agreement in assessing mobile apps [<xref ref-type="bibr" rid="ref12">12</xref>]. It assesses the inclusion and interactivity of 20 intervention strategies which are shared by four key models/theories: (1) Health Belief Model, (2) Theory of Planned Behavior, (3) Transtheoretical Model, and (4) Social Cognitive Theory. While studies have found mobile apps are not usually based on behavioral theory [<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref12">12</xref>], many incorporate highly interactive strategies which may support therapy.</p>
            <p>This paper presents an approach to assist health professionals in recommending high-quality apps for supporting chronic disease self-management. The framework developed aims to be methodologically sound, capable of selecting popular apps which include content covered by evidence-based programs and consistent with behavioral theory, and a patient-centered approach for matching apps to patients&#8217; individual needs. A single disease&#8212;type 2 diabetes&#8212;was selected to illustrate how the framework can be applied as this was deemed to represent the types of strategies used in most chronic diseases.</p>
        </sec>
        <sec sec-type="methods">
            <title>Methods</title>
            <sec>
                <title>Framework</title>
                <p>We used a three-step process for selecting, categorizing, and matching apps to patients' needs (see <xref ref-type="fig" rid="figure1">Figure 1</xref>): (1) identification of popular, high-quality apps which include content covered by evidence-based programs, (2) categorization of apps based on topics and core intervention strategies, and (3) a patient-centered approach for matching apps to patients&#8217; needs.</p>
                <fig id="figure1" position="float">
                    <label>Figure 1</label>
                    <caption>
                        <p>Framework for selecting, categorizing, and matching apps to patients' needs.</p>
                    </caption>
                    <graphic xlink:href="mhealth_v3i3e87_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple" />
                </fig>
            </sec>
            <sec>
                <title>App Identification</title>
                <p>Using type 2 diabetes as an example in adopting the framework, our aim was to identify popular, high-quality health apps which are consistent with type 2 diabetes evidence-based guidelines.</p>
                <p>Apps were selected based on 29 topics identified from the following: (1) patient education topics recommended in the Canadian Diabetes Association 2013 Clinical Practice Guidelines for the Prevention and Management of Diabetes [<xref ref-type="bibr" rid="ref6">6</xref>] and (2) the seven self-management behaviors identified by the American Association of Diabetes Educators [<xref ref-type="bibr" rid="ref13">13</xref>]. The topics were grouped into five categories: (1) healthy eating, (2) physical activity, (3) self-monitoring, (4) problem solving, and (5) healthy coping.</p>
                <p>A series of search strategies were used to identify eligible health apps available in the Apple App Store and Google Play in March 2014. The apps were first identified from extensive searches of the Apple App Store as it contains the largest number of health apps [<xref ref-type="bibr" rid="ref14">14</xref>]. Availability was then cross-checked in Google Play. App descriptions and information provided by the Apple App Store were used in the initial screening process. Apps were downloaded to an iPhone and fully explored before selection.</p>
                <p>First a search of &#34;Top 200 Free&#34; and &#34;Top 200 Grossing&#34; general and health apps in the Apple App Store was conducted to identify the most downloaded free health apps and the paid health apps generating the most revenue. This was followed by a broad search using the keyword &#34;diabetes.&#34; More refined keyword searches followed using keywords specific to topics where less than four apps had been identified in the broader searches including &#34;GI&#34; (glycemic index), &#34;glycemic index,&#34; &#34;relaxation,&#34; &#34;confidence,&#34; and &#34;CBT&#34; (cognitive behavioral therapy). Each selected app was then individually searched in the Google Play Store. Only free and low-cost (ie, less than AUD $5) apps were selected from refined searches as they dominate app purchases [<xref ref-type="bibr" rid="ref15">15</xref>].</p>
                <p>Apps were selected based on the following inclusion criteria: (1) consistent with the 29 app topics, (2) less than AUD $5, and (3) written in English. Apps were excluded if they (1) did not support the International System of Units (SI) of measurements, (2) required extra components to function, (3) were designed specifically for children, (4) did not describe how food databases were compiled, (5) were designed specifically for type 1 diabetes, (6) marketed specific products, and/or (7) contained information that was assessed as inaccurate, biased, or unsafe.</p>
            </sec>
            <sec>
                <title>App Categorization</title>
                <p>The apps were grouped according to topic and core intervention strategies. The primary author (KH), having a special interest in health behavior theory, identified the core intervention strategies of each app using the Behaviour Theory Content Survey (see <xref ref-type="table" rid="table1">Table 1</xref>) [<xref ref-type="bibr" rid="ref16">16</xref>]. A copy of the evaluation template can be obtained by request from Doshi et al [<xref ref-type="bibr" rid="ref16">16</xref>].</p>
                <table-wrap position="float" id="table1">
                    <label>Table 1</label>
                    <caption>
                        <p>Behavioral Theory Content Survey<sup>a</sup>: intervention strategies by behavior change model or theory.</p>
                    </caption>
                    <table width="800" border="1" cellpadding="7" cellspacing="0" rules="groups" frame="hsides">
                        <col width="52" />
                        <col width="160" />
                        <col width="90" />
                        <col width="99" />
                        <col width="90" />
                        <col width="90" />
                        <thead>
                            <tr valign="bottom">
                                <td>Strategy No.</td>
                                <td>Intervention strategies<sup>b</sup>
                                </td>
                                <td>Health Belief Model</td>
                                <td>Transtheoretical Model</td>
                                <td>Theory of Planned Behavior</td>
                                <td>Social Cognitive Theory</td>
                            </tr>
                        </thead>
                        <tbody>
                            <tr valign="top">
                                <td>1</td>
                                <td>General information (K)</td>
                                <td>X</td>
                                <td>X</td>
                                <td>X</td>
                                <td>X</td>
                            </tr>
                            <tr valign="top">
                                <td>2</td>
                                <td>Perceived benefits (C)</td>
                                <td>X</td>
                                <td>X</td>
                                <td>X</td>
                                <td>X</td>
                            </tr>
                            <tr valign="top">
                                <td>3</td>
                                <td>Perceived barriers (C)</td>
                                <td>X</td>
                                <td>X</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                            </tr>
                            <tr valign="top">
                                <td>4</td>
                                <td>Perceived risks (C)</td>
                                <td>X</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                                <td>
                                    <break />
                                </td>
                            </tr>
                            <tr valign="top">
                                <td>5</td>
                                <td>Self-efficacy (C)</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                                <td>X</td>
                                <td>X</td>
                            </tr>
                            <tr valign="top">
                                <td>6</td>
                                <td>Self-talk (C)</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                            </tr>
                            <tr valign="top">
                                <td>7</td>
                                <td>Perceived social norms (C)</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                                <td>X</td>
                                <td>
                                    <break />
                                </td>
                            </tr>
                            <tr valign="top">
                                <td>8</td>
                                <td>Self-monitoring (B)</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                            </tr>
                            <tr valign="top">
                                <td>9</td>
                                <td>Realistic goal setting (B)</td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                            </tr>
                            <tr valign="top">
                                <td>10</td>
                                <td>Time management (B)</td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                            </tr>
                            <tr valign="top">
                                <td>11</td>
                                <td>Stimulus control (B)</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                            </tr>
                            <tr valign="top">
                                <td>12</td>
                                <td>Self-reward (B)</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                            </tr>
                            <tr valign="top">
                                <td>13</td>
                                <td>Social support (B)</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                            </tr>
                            <tr valign="top">
                                <td>14</td>
                                <td>Modeling/vicarious learning (B)</td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                            </tr>
                            <tr valign="top">
                                <td>15</td>
                                <td>Relapse prevention (B)</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                            </tr>
                            <tr valign="top">
                                <td>16</td>
                                <td>Stress management (EF)</td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                            </tr>
                            <tr valign="top">
                                <td>17</td>
                                <td>Negative affect management (EF)</td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                            </tr>
                            <tr valign="top">
                                <td>18</td>
                                <td>Skill building/overview (T)</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                            </tr>
                            <tr valign="top">
                                <td>19</td>
                                <td>Increasing knowledge (T)</td>
                                <td>X</td>
                                <td>X</td>
                                <td>X</td>
                                <td>
                                    <break />
                                </td>
                            </tr>
                            <tr valign="top">
                                <td>20</td>
                                <td>Motivational readiness (T)</td>
                                <td>
                                    <break />
                                </td>
                                <td>X</td>
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>No. strategies per model/theory</td>
                                <td>5</td>
                                <td>14</td>
                                <td>6</td>
                                <td>16</td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <fn id="table1fn1">
                            <p>
                                <sup>a</sup>With kind permission from Springer Science+Business Media: &#60; Ann Behav Med, Evaluation of physical activity web sites for use of behavior change theories, volume 25, 2003, p107, Doshi A, Patrick K, Sallis JF, et al, <xref ref-type="table" rid="table1">Table 1</xref>&#62; [<xref ref-type="bibr" rid="ref16">16</xref>].</p>
                        </fn>
                        <fn id="table1fn2">
                            <p>
                                <sup>b</sup>Knowledge (K), cognitive (C), behavioral (B), emotion focused (EF), therapeutic (T).</p>
                        </fn>
                    </table-wrap-foot>
                </table-wrap>
                <p>The Behavior Theory Content Survey [<xref ref-type="bibr" rid="ref16">16</xref>] assesses interventions for the use of 20 strategies (see <xref ref-type="table" rid="table1">Table 1</xref>) shared by four key behavioral models/theories: (1) Health Belief Model, (2) Theory of Planned Behavior, (3) Transtheoretical Model, and (4) Social Cognitive Theory. The strategies are listed individually as they are common to more than one theory. Each intervention strategy is scored out of 5 as it is rated dichotomously for the inclusion of the following five dimensions of user interaction: (1) provides general information or guidelines, (2) assesses current practices or use of strategies, (3) provides feedback on assessment, (4) offers general assistance on behavior change, and (5) offers individually tailored assistance in response to assessment and feedback. The levels are hierarchical as level 5 (individual advice) is thought to be more effective than level 1 (providing general information). The BTS is the sum of scores for all 20 intervention strategies; the maximum BTS score is 100, representing 20 strategies, each of which are scored out of 5 to indicate the level of interactivity.</p>
            </sec>
            <sec>
                <title>Matching Apps to Patients&#8217; Needs</title>
                <p>Health practitioners work with patients (within consultations) to identify core problems and root causes or etiology of problems. Using a patient-centered approach, conventional interventions are usually selected based on problem etiology and patient motivation. We propose that in step 1 apps be selected using the same process, as they are simply another intervention and should complement other therapies. In step 2, the apps are grouped together according to topic and core intervention strategy. Presenting these categories in a table can aid health practitioners in matching apps to the patient&#8217;s needs. The primary author (KH) tested the process within dietetic consultations in a primary care setting to determine its usefulness. Next, the tool was further developed based on feedback from a convenience sample of experienced health professionals teaching and examining nutrition therapy.</p>
            </sec>
        </sec>
        <sec sec-type="results">
            <title>Results</title>
            <sec>
                <title>App Identification</title>
                <p>Only 4 health apps were recovered from the top 200 free and grossing app searches but they were not specific to diabetes; for example, 2 were exercise apps and 2 were diet-focused apps. Out of the 4 health apps, only 1&#8212;clean eating diet app&#8212;was ranked in the top 100, and only 2 health apps&#8212;exercise apps&#8212;met the inclusion criteria.</p>
                <p>The most popular free health apps were diet and physical activity apps, and the paid apps generating the most revenue were physical activity and relaxation/meditation apps. The 53 apps which met the eligibility criteria were general diet, physical activity, and relaxation apps. There were no diabetes-specific apps identified in the top or grossing Apple App Store and health app searches.</p>
                <p>The 919 apps recovered using the &#34;diabetes&#34; keyword search were a mixture of free and paid apps, including diabetes-specific and general apps. A total of 37 apps met the inclusion criteria and these included diabetes goal-setting, general diet, and general physical activity tracker apps. Fewer than 4 apps were identified from all searches for the topic areas relating to diabetes-specific healthy eating, problem solving, and healthy coping.</p>
                <p>An additional 3 apps were recovered using the refined keyword searches, including 2 relaxation apps and 1 CBT app. The search strategies did not recover any eligible diabetes-specific diet apps.</p>
                <p>A total of 68 apps were excluded as they were not available on Google Play. A total of 27 apps were available for both iPhone and Android platforms.</p>
            </sec>
            <sec>
                <title>App Categorization</title>
                <sec>
                    <title>App Topics</title>
                    <p>Apps were identified for all five topics (see <xref ref-type="table" rid="table2">Table 2</xref>). General apps were relevant to, and could be grouped into, more than one topic. A wider variety of apps were identified for healthy eating and physical activity than for other topic areas.</p>
                    <table-wrap position="float" id="table2">
                        <label>Table 2</label>
                        <caption>
                            <p>Categorization of app types by topic.</p>
                        </caption>
                        <table width="422" border="1" cellpadding="7" cellspacing="0" rules="groups" frame="hsides">
                            <col width="154" />
                            <col width="238" />
                            <thead>
                                <tr valign="top">
                                    <td>Topic categories</td>
                                    <td>App types</td>
                                </tr>
                            </thead>
                            <tbody>
                                <tr valign="top">
                                    <td>Healthy eating</td>
                                    <td>Diet tracker<break />Food selection<break />Menu planning<break />Diabetes-specific goal trackers<break />General goal tracker<break />Coaching<break />Cognitive behavioral therapy</td>
                                </tr>
                                <tr valign="top">
                                    <td>Physical activity</td>
                                    <td>Exercise trackers<break />Resistance exercise<break />Diabetes-specific goal trackers<break />General goal tracker<break />Cognitive behavioral therapy</td>
                                </tr>
                                <tr valign="top">
                                    <td>Self-monitoring</td>
                                    <td>Diabetes tracker<break />Expert support</td>
                                </tr>
                                <tr valign="top">
                                    <td>Problem solving</td>
                                    <td>Coaching<break />Peer support</td>
                                </tr>
                                <tr valign="top">
                                    <td>Healthy coping</td>
                                    <td>Cognitive behavioral therapy<break />Peer support<break />Relaxation</td>
                                </tr>
                            </tbody>
                        </table>
                    </table-wrap>
                </sec>
                <sec>
                    <title>Behavioral Theory Content Analysis</title>
                    <p>Similar apps were grouped together, and only the results for the highest-scoring app for each of the 14 app types are reported in <xref ref-type="table" rid="table3">Table 3</xref>.</p>
                    <table-wrap position="float" id="table3">
                        <label>Table 3</label>
                        <caption>
                            <p>Total Behavioral Theory Survey score and individual component scores of those apps scoring best in type.</p>
                        </caption>
                        <table width="665" border="1" cellpadding="7" cellspacing="0" rules="groups" frame="hsides">
                            <col width="117" />
                            <col width="36" />
                            <col width="33" />
                            <col width="38" />
                            <col width="40" />
                            <col width="39" />
                            <col width="35" />
                            <col width="41" />
                            <col width="33" />
                            <col width="37" />
                            <col width="61" />
                            <thead>
                                <tr valign="bottom">
                                    <td>App type</td>
                                    <td colspan="4">Therapy/model scores<sup>a</sup>
                                    </td>
                                    <td colspan="5">Strategy category scores</td>
                                    <td>Total BTS scores<sup>b</sup>
                                    </td>
                                </tr>
                                <tr valign="bottom">
                                    <td>
                                        <break />
                                    </td>
                                    <td>HBM<sup>c</sup>
                                    </td>
                                    <td>TTM<sup>d</sup>
                                    </td>
                                    <td>TPB<sup>e</sup>
                                    </td>
                                    <td>SCT<sup>f</sup>
                                    </td>
                                    <td>K<sup>g</sup>
                                    </td>
                                    <td>C<sup>h</sup>
                                    </td>
                                    <td>B<sup>i</sup>
                                    </td>
                                    <td>EF<sup>j</sup>
                                    </td>
                                    <td>T<sup>k</sup>
                                    </td>
                                    <td />
                                </tr>
                            </thead>
                            <tbody>
                                <tr valign="top">
                                    <td>General goals</td>
                                    <td>3</td>
                                    <td>21</td>
                                    <td>7</td>
                                    <td>29</td>
                                    <td>3</td>
                                    <td>4</td>
                                    <td>22</td>
                                    <td>0</td>
                                    <td>2</td>
                                    <td>31</td>
                                </tr>
                                <tr valign="top">
                                    <td>Exercise tracker</td>
                                    <td>2</td>
                                    <td>21</td>
                                    <td>6</td>
                                    <td>26</td>
                                    <td>1</td>
                                    <td>4</td>
                                    <td>20</td>
                                    <td>1</td>
                                    <td>3</td>
                                    <td>29</td>
                                </tr>
                                <tr valign="top">
                                    <td>Diabetes goals</td>
                                    <td>5</td>
                                    <td>21</td>
                                    <td>9</td>
                                    <td>24</td>
                                    <td>2</td>
                                    <td>5</td>
                                    <td>17</td>
                                    <td>0</td>
                                    <td>5</td>
                                    <td>29</td>
                                </tr>
                                <tr valign="top">
                                    <td>Diet tracker</td>
                                    <td>7</td>
                                    <td>19</td>
                                    <td>9</td>
                                    <td>19</td>
                                    <td>3</td>
                                    <td>5</td>
                                    <td>10</td>
                                    <td>2</td>
                                    <td>5</td>
                                    <td>25</td>
                                </tr>
                                <tr valign="top">
                                    <td>Cognitive behavioral therapy</td>
                                    <td>5</td>
                                    <td>18</td>
                                    <td>6</td>
                                    <td>23</td>
                                    <td>1</td>
                                    <td>10</td>
                                    <td>5</td>
                                    <td>4</td>
                                    <td>4</td>
                                    <td>24</td>
                                </tr>
                                <tr valign="top">
                                    <td>Resistance exercise</td>
                                    <td>7</td>
                                    <td>16</td>
                                    <td>8</td>
                                    <td>19</td>
                                    <td>2</td>
                                    <td>5</td>
                                    <td>10</td>
                                    <td>1</td>
                                    <td>5</td>
                                    <td>23</td>
                                </tr>
                                <tr valign="top">
                                    <td>Mindfulness</td>
                                    <td>4</td>
                                    <td>14</td>
                                    <td>5</td>
                                    <td>21</td>
                                    <td>1</td>
                                    <td>5</td>
                                    <td>7</td>
                                    <td>6</td>
                                    <td>3</td>
                                    <td>22</td>
                                </tr>
                                <tr valign="top">
                                    <td>Coaching</td>
                                    <td>7</td>
                                    <td>17</td>
                                    <td>5</td>
                                    <td>20</td>
                                    <td>2</td>
                                    <td>7</td>
                                    <td>7</td>
                                    <td>2</td>
                                    <td>3</td>
                                    <td>21</td>
                                </tr>
                                <tr valign="top">
                                    <td>Menu planning</td>
                                    <td>4</td>
                                    <td>13</td>
                                    <td>4</td>
                                    <td>18</td>
                                    <td>1</td>
                                    <td>3</td>
                                    <td>12</td>
                                    <td>0</td>
                                    <td>3</td>
                                    <td>19</td>
                                </tr>
                                <tr valign="top">
                                    <td>Peer support</td>
                                    <td>2</td>
                                    <td>9</td>
                                    <td>5</td>
                                    <td>12</td>
                                    <td>0</td>
                                    <td>4</td>
                                    <td>9</td>
                                    <td>2</td>
                                    <td>1</td>
                                    <td>16</td>
                                </tr>
                                <tr valign="top">
                                    <td>Expert support</td>
                                    <td>2</td>
                                    <td>12</td>
                                    <td>3</td>
                                    <td>14</td>
                                    <td>1</td>
                                    <td>1</td>
                                    <td>9</td>
                                    <td>1</td>
                                    <td>3</td>
                                    <td>15</td>
                                </tr>
                                <tr valign="top">
                                    <td>Food choice</td>
                                    <td>7</td>
                                    <td>11</td>
                                    <td>8</td>
                                    <td>9</td>
                                    <td>4</td>
                                    <td>2</td>
                                    <td>1</td>
                                    <td>0</td>
                                    <td>4</td>
                                    <td>11</td>
                                </tr>
                                <tr valign="top">
                                    <td>Diabetes tracker</td>
                                    <td>0</td>
                                    <td>9</td>
                                    <td>3</td>
                                    <td>9</td>
                                    <td>0</td>
                                    <td>3</td>
                                    <td>8</td>
                                    <td>0</td>
                                    <td>0</td>
                                    <td>11</td>
                                </tr>
                                <tr valign="top">
                                    <td>Relaxation</td>
                                    <td>1</td>
                                    <td>4</td>
                                    <td>2</td>
                                    <td>9</td>
                                    <td>0</td>
                                    <td>1</td>
                                    <td>1</td>
                                    <td>5</td>
                                    <td>3</td>
                                    <td>10</td>
                                </tr>
                                <tr valign="top">
                                    <td>Mean score (SD)</td>
                                    <td>4.0<break />(2.4)</td>
                                    <td>14.6<break />(5.3)</td>
                                    <td>5.7<break />(2.3)</td>
                                    <td>18.0<break />(6.5)</td>
                                    <td>1.5<break />(1.2)</td>
                                    <td>4.2<break />(2.4)</td>
                                    <td>9.9<break />(6.2)</td>
                                    <td>1.7<break />(2.0)</td>
                                    <td>3.1<break />(1.5)</td>
                                    <td>20.4<break />(7.0)</td>
                                </tr>
                            </tbody>
                        </table>
                        <table-wrap-foot>
                            <fn id="table3fn1">
                                <p>
                                    <sup>a</sup>Scores do not add up to 100 as the 20 strategies can map to more than one model/theory.</p>
                            </fn>
                            <fn id="table3fn2">
                                <p>
                                    <sup>b</sup>The Behavioral Theory Survey (BTS) score only counts each strategy once and therefore is the sum of the strategy categories; maximum BTS score is 100.</p>
                            </fn>
                            <fn id="table3fn3">
                                <p>
                                    <sup>c</sup>Health Belief Model (HBM); maximum score is 25.</p>
                            </fn>
                            <fn id="table3fn4">
                                <p>
                                    <sup>d</sup>Transtheoretical Model (TTM); maximum score is 70.</p>
                            </fn>
                            <fn id="table3fn5">
                                <p>
                                    <sup>e</sup>Theory of Planned Behavior (TPB); maximum score is 30.</p>
                            </fn>
                            <fn id="table3fn6">
                                <p>
                                    <sup>f</sup>Social Cognitive Theory (SCT); maximum score is 80.</p>
                            </fn>
                            <fn id="table3fn7">
                                <p>
                                    <sup>g</sup>Knowledge (K); maximum score is 5.</p>
                            </fn>
                            <fn id="table3fn8">
                                <p>
                                    <sup>h</sup>Cognitive (C); maximum score is 30.</p>
                            </fn>
                            <fn id="table3fn9">
                                <p>
                                    <sup>i</sup>Behavioral (B); maximum score is 40.</p>
                            </fn>
                            <fn id="table3fn10">
                                <p>
                                    <sup>j</sup>Emotion focused (EF); maximum score is 10.</p>
                            </fn>
                            <fn id="table3fn11">
                                <p>
                                    <sup>k</sup>Therapeutic (T); maximum score is 15.</p>
                            </fn>
                        </table-wrap-foot>
                    </table-wrap>
                </sec>
                <sec>
                    <title>App Scores</title>
                    <p>The total BTS scores are shown in the last column of <xref ref-type="table" rid="table3">Table 3</xref>. The mean total BTS score was 20.4 (SD 7.0) out of 100. Apps more often included behavioral (mean 9.9/40, SD 6.2) and knowledge strategies (mean 1.5/5, SD 1.2), and less often used cognitive (mean 4.2/30, SD 2.4) and emotion-focused strategies (mean 1.7/10, SD 2.0). Mean scores for all behavioral models/theories were less than 25% of the total possible scores; scores were highest for Social Cognitive Theory (mean 18.0/80, SD 6.5).</p>
                    <p>Most apps (11/14, 79%) incorporated more than 50% of the different intervention strategies, but within each strategy, scores were generally less than 2 out of 5. However, all apps included at least one strategy (mean 2.3, SD 1.1) that scored higher than 2 out of 5. Highly interactive intervention strategies, including self-monitoring, social support, modelling/vicarious learning, and stimulus control, were those most commonly included (see <xref ref-type="table" rid="table4">Table 4</xref>).</p>
                    <table-wrap position="float" id="table4">
                        <label>Table 4</label>
                        <caption>
                            <p>Intervention strategy distribution by all apps.</p>
                        </caption>
                        <table width="590" border="1" cellpadding="7" cellspacing="0" rules="groups" frame="hsides">
                            <col width="194" />
                            <col width="137" />
                            <col width="99" />
                            <col width="101" />
                            <thead>
                                <tr valign="bottom">
                                    <td>Intervention strategy</td>
                                    <td>Intervention category</td>
                                    <td>Apps using strategy, n</td>
                                    <td>Apps with<break />BTS<sup>a</sup>&#62;2/5<sup>b</sup>, n</td>
                                </tr>
                            </thead>
                            <tbody>
                                <tr valign="top">
                                    <td>Self-monitoring</td>
                                    <td>Behavioral</td>
                                    <td>12</td>
                                    <td>6</td>
                                </tr>
                                <tr valign="top">
                                    <td>Skill building/overview</td>
                                    <td>Therapeutic</td>
                                    <td>12</td>
                                    <td>2</td>
                                </tr>
                                <tr valign="top">
                                    <td>Social support</td>
                                    <td>Behavioral</td>
                                    <td>10</td>
                                    <td>4</td>
                                </tr>
                                <tr valign="top">
                                    <td>Modeling/vicarious learning</td>
                                    <td>Behavioral</td>
                                    <td>10</td>
                                    <td>5</td>
                                </tr>
                                <tr valign="top">
                                    <td>General information</td>
                                    <td>Knowledge</td>
                                    <td>11</td>
                                    <td>3</td>
                                </tr>
                                <tr valign="top">
                                    <td>Stimulus control</td>
                                    <td>Behavioral</td>
                                    <td>11</td>
                                    <td>5</td>
                                </tr>
                                <tr valign="top">
                                    <td>Realistic goal setting</td>
                                    <td>Behavioral</td>
                                    <td>10</td>
                                    <td>2</td>
                                </tr>
                                <tr valign="top">
                                    <td>Self-efficacy</td>
                                    <td>Cognitive</td>
                                    <td>14</td>
                                    <td>0</td>
                                </tr>
                                <tr valign="top">
                                    <td>Increasing knowledge</td>
                                    <td>Therapeutic</td>
                                    <td>11</td>
                                    <td>1</td>
                                </tr>
                                <tr valign="top">
                                    <td>Negative affect management</td>
                                    <td>Emotion focused</td>
                                    <td>9</td>
                                    <td>2</td>
                                </tr>
                                <tr valign="top">
                                    <td>Perceived social norms</td>
                                    <td>Cognitive</td>
                                    <td>7</td>
                                    <td>0</td>
                                </tr>
                                <tr valign="top">
                                    <td>Perceived barriers</td>
                                    <td>Cognitive</td>
                                    <td>6</td>
                                    <td>1</td>
                                </tr>
                                <tr valign="top">
                                    <td>Time management</td>
                                    <td>Behavioral</td>
                                    <td>6</td>
                                    <td>1</td>
                                </tr>
                                <tr valign="top">
                                    <td>Stress management</td>
                                    <td>Emotion focused</td>
                                    <td>5</td>
                                    <td>2</td>
                                </tr>
                                <tr valign="top">
                                    <td>Self-talk</td>
                                    <td>Cognitive</td>
                                    <td>2</td>
                                    <td>1</td>
                                </tr>
                                <tr valign="top">
                                    <td>Perceived benefits</td>
                                    <td>Cognitive</td>
                                    <td>6</td>
                                    <td>1</td>
                                </tr>
                                <tr valign="top">
                                    <td>Perceived risks</td>
                                    <td>Cognitive</td>
                                    <td>5</td>
                                    <td>0</td>
                                </tr>
                                <tr valign="top">
                                    <td>Self-reward</td>
                                    <td>Behavioral</td>
                                    <td>3</td>
                                    <td>0</td>
                                </tr>
                                <tr valign="top">
                                    <td>Relapse prevention</td>
                                    <td>Behavioral</td>
                                    <td>2</td>
                                    <td>0</td>
                                </tr>
                                <tr valign="top">
                                    <td>Motivational readiness</td>
                                    <td>Therapeutic</td>
                                    <td>1</td>
                                    <td>0</td>
                                </tr>
                            </tbody>
                        </table>
                        <table-wrap-foot>
                            <fn id="table4fn1">
                                <p>
                                    <sup>a</sup>Behavioral Theory Survey (BTS).</p>
                            </fn>
                            <fn id="table4fn2">
                                <p>
                                    <sup>b</sup>Number of apps that scored &#62;2 out of 5 for the intervention strategy. A score above 2 indicates tailored advice or assistance.</p>
                            </fn>
                        </table-wrap-foot>
                    </table-wrap>
                </sec>
            </sec>
            <sec>
                <title>Matching Apps to Patients&#8217; Needs</title>
                <p>
                    <xref ref-type="table" rid="table5">Table 5</xref> shows how app categorization can be used to assist practitioners in matching apps to patients&#8217; needs.</p>
                <table-wrap position="float" id="table5">
                    <label>Table 5</label>
                    <caption>
                        <p>Matching apps using type 2 diabetes as an example.</p>
                    </caption>
                    <table width="800" border="1" cellpadding="7" cellspacing="0" rules="groups" frame="hsides">
                        <col width="141" />
                        <col width="106" />
                        <col width="142" />
                        <col width="184" />
                        <thead>
                            <tr valign="top">
                                <td colspan="2">Topic and intervention category:<break />selection based on problem etiology and patient motivation identified during usual practice</td>
                                <td colspan="2">App type and core intervention strategies:<break />selection based on patient preference identified during usual practice</td>
                            </tr>
                            <tr valign="bottom">
                                <td>Topic category</td>
                                <td>Intervention category</td>
                                <td>App type</td>
                                <td>Core intervention strategies<sup>a</sup>
                                </td>
                            </tr>
                        </thead>
                        <tbody>
                            <tr valign="top">
                                <td>Healthy eating</td>
                                <td>Knowledge</td>
                                <td>Diet tracker</td>
                                <td>General knowledge</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>Food selection</td>
                                <td>General knowledge</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Cognitive</td>
                                <td>Coaching</td>
                                <td>Perceived barriers</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>Cognitive behavioral therapy</td>
                                <td>Self-talk</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Behavioral</td>
                                <td>Diet tracker</td>
                                <td>Self-monitoring</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>General goal tracker</td>
                                <td>Self-monitoring<break />Realistic goal setting<break />Social support<break />Modeling/vicarious learning</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>Menu planning</td>
                                <td>Time management</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>Diabetes-specific goal tracker</td>
                                <td>Self-monitoring<break />Realistic goal setting<break />Social support<break />Modeling/vicarious learning</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>Coaching</td>
                                <td>Stimulus control</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Emotion focused</td>
                                <td>Cognitive behavioral therapy</td>
                                <td>Negative affect management</td>
                            </tr>
                            <tr valign="top">
                                <td>Physical activity</td>
                                <td>Cognitive</td>
                                <td>Cognitive behavioral therapy</td>
                                <td>Self-talk</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Behavioral</td>
                                <td>Exercise tracker</td>
                                <td>Self-monitoring<break />Social support<break />Modeling/vicarious learning</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>Resistance exercise</td>
                                <td>Self-monitoring<break />Modelling/vicarious learning</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>Diabetes-specific goal tracker</td>
                                <td>Self-monitoring<break />Realistic goal setting<break />Social support<break />Modeling/vicarious learning</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>General goal tracker</td>
                                <td>Self-monitoring<break />Realistic goal setting<break />Social support<break />Modeling/vicarious learning</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Emotion focused</td>
                                <td>Cognitive behavioral therapy</td>
                                <td>Negative affect management</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Therapeutic</td>
                                <td>Resistance exercise</td>
                                <td>Skill building/overview</td>
                            </tr>
                            <tr valign="top">
                                <td>Self-monitoring</td>
                                <td>Behavioral</td>
                                <td>Diabetes tracker</td>
                                <td>Self-monitoring</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>Expert support</td>
                                <td>Stimulus control</td>
                            </tr>
                            <tr valign="top">
                                <td>Problem solving</td>
                                <td>Cognitive</td>
                                <td>Coaching</td>
                                <td>Perceived barriers</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Behavioral</td>
                                <td>Peer support</td>
                                <td>Social support<break />Modeling/vicarious learning</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>Coaching</td>
                                <td>Stimulus control</td>
                            </tr>
                            <tr valign="top">
                                <td>Healthy coping</td>
                                <td>Cognitive</td>
                                <td>Cognitive behavioral therapy</td>
                                <td>Self-talk</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Behavioral</td>
                                <td>Peer support</td>
                                <td>Social support<break />Modeling/vicarious learning</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>Mindfulness</td>
                                <td>Stimulus control</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Emotion focused</td>
                                <td>Cognitive behavioral therapy</td>
                                <td>Negative affect management</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>Relaxation</td>
                                <td>Stress management<break />Negative affect management</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>Mindfulness</td>
                                <td>Stress management<break />Negative affect management</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>Therapeutic</td>
                                <td>Cognitive behavioral therapy</td>
                                <td>Skill building/overview</td>
                            </tr>
                            <tr valign="top">
                                <td>
                                    <break />
                                </td>
                                <td>
                                    <break />
                                </td>
                                <td>Mindfulness</td>
                                <td>Skill building/overview</td>
                            </tr>
                        </tbody>
                    </table>
                    <table-wrap-foot>
                        <fn id="table5fn1">
                            <p>
                                <sup>a</sup>Strategies with Behavioral Theory Survey Scores of &#62;2/5. A score above 2 indicates tailored advice or assistance.</p>
                        </fn>
                    </table-wrap-foot>
                </table-wrap>
            </sec>
        </sec>
        <sec sec-type="discussion">
            <title>Discussion</title>
            <sec>
                <title>Principal Findings</title>
                <p>In this paper we proposed a framework to assist health professionals in recommending high-quality apps for supporting chronic disease self-management. We used type 2 diabetes to illustrate the processes used in (1) creating the app library, (2) identifying core intervention strategies incorporated into apps, and (3) a patient-centered approach to match apps to patient needs.</p>
                <p>Our library included apps that incorporated highly interactive strategies from all of the intervention categories. This is different from other studies where the primary focus of the mobile interventions was self-monitoring [<xref ref-type="bibr" rid="ref4">4</xref>,<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref17">17</xref>]. For example, Azar et al [<xref ref-type="bibr" rid="ref10">10</xref>] found that weight-management apps incorporated mostly behavioral and knowledge strategies and did not use emotion-focused strategies. We selected the most popular apps for topics based on the recommendations from published international guidelines for the management of diabetes, whereas Azar et al [<xref ref-type="bibr" rid="ref10">10</xref>] searched for a specific type of app (tracker) and included the most popular. Using our search strategy we were able to recover apps that specifically focused on emotion-focused and cognitive strategies.</p>
                <p>The behavioral content analysis revealed that most of the apps (11/14, 78%) included more than 50% of theoretical strategies, but total BTS scores were low as few of the highly personalized interactive strategies were included. Apps mostly provided general information and general assistance to users with limited assessment, feedback, or tailored assistance. While apps scored poorly overall, they tended to score high for specific strategies related to their primary focus. Higher-scoring strategies, such as self-monitoring, goal setting, and social support, are associated with healthy eating, higher dietary self-efficacy [<xref ref-type="bibr" rid="ref18">18</xref>], and Social Cognitive Theory which has been used extensively to explain dietary behavior.</p>
                <p>Behavioral theories such as SCT indicate that stand-alone apps would need to use specific combinations of high-scoring strategies to be effective. <xref ref-type="table" rid="table3">Table 3</xref> illustrates that all of the apps scored less than 50% of the total possible BTS scores for all four of the behavioral models/theories. The results suggest that even when apps incorporate highly interactive intervention strategies, they cannot replace human factors such as empathy and understanding as they seem not to incorporate sufficient emotion-focused and cognitive strategies. It is as yet unclear if apps that incorporate many strategies would be effective. The general apps would be relevant for a range of chronic diseases. The low scores indicate that a mixture of apps using complementary strategies or apps used in conjunction with more highly interactive interventions would be more effective than solitary apps. Other studies have found mobile interventions are most effective when used as an adjunct to therapy [<xref ref-type="bibr" rid="ref17">17</xref>,<xref ref-type="bibr" rid="ref19">19</xref>].</p>
                <p>Mobile apps may support and reinforce many aspects of therapy. Tracker apps track symptoms and behavior and are useful to both the health practitioner and the patient. Patients become more aware of their symptoms and behaviors when using assessment apps and this may increase their participation in decision making. Newer technologies objectively estimate food intake and physical activity, reducing demands on users and reliance on self-report. Strategies and goals for behavior change identified in therapy can be programmed into goal-tracking apps which patients can use to prompt new behaviors and monitor progress between visits. Many apps guide patients when practicing new skills and have functions including reminders and social connectivity, which can be used to stimulate desired behavior. App reminders can shape behavior by prompting new behaviors and reminding the patients of motivations for change at predetermined times. Patients can receive encouragement and emotional support from peers via social connectivity. Mobile apps may allow health practitioners to spend less time on assessment and providing general information, and more time on supporting behavior change.</p>
            </sec>
            <sec>
                <title>Practical Application</title>
                <p>When used as an adjunct, high-quality health apps may increase the effectiveness of therapy [<xref ref-type="bibr" rid="ref17">17</xref>,<xref ref-type="bibr" rid="ref19">19</xref>]. However, patients need guidance from health practitioners for matching apps to their health needs and goals. <xref ref-type="table" rid="table5">Table 5</xref> outlines a patient-centered approach for matching apps to patients' needs, preferences, and motivations identified during usual practice. The topic and app category could be based primarily on patient motivation and the etiology of the problem, and the core theoretical strategies of the app could be selected based on patient preference. For example, the diet tracker and/or the food selection app may be the best option(s) for a patient who is motivated to lose weight, wants to focus on diet, and has a food and nutrition knowledge deficit. The diet tracker app will increase the patient&#8217;s awareness of how their diet compares to their nutritional goals and will support them in pinpointing less desirable food choices in their diet; the food selection app could be used to identify healthier alternatives.</p>
                <p>High-quality apps that are customized to patients&#8217; needs will deliver appropriate guidance, feedback, and triggers for new behaviors, thereby providing intensive support between appointments. It is important that health practitioners provide guidance on how to customize app goals and interpret automated feedback, and provide patients with tailored assistance in further modifying behavior in response to app feedback at follow-up appointments. Empowering patients to use apps should increase their active participation in managing their health. The framework could be used as a basis for future research evaluating the effectiveness of behaviorally based, mobile interventions.</p>
            </sec>
            <sec>
                <title>Strengths and Limitations</title>
                <p>The framework presented here is a systematic and methodological approach that was well accepted and understood by a convenience sample of health practitioners. App selection was based on topics recommended in published international guidelines for the management of diabetes, and general criteria focusing on the health practitioners' assessment of information quality and reliability. It uses behavioral theory to explain how apps may be used to support therapy. Studies show mobile text-messaging interventions based on behavioral theory are more effective than non-theory-based ones [<xref ref-type="bibr" rid="ref20">20</xref>]. Best practice guidelines for chronic disease management of lifestyle-related problems in general recommend basing interventions on behavior change theory. Our framework can be adapted to other conditions, as behavioral theory helps in identifying strategies which match patient needs.</p>
                <p>Additionally, the framework can be flexibly delivered to meet practitioners&#8217; needs. For example, some practitioners may not have the time to build the library from scratch, and instead prefer to build it based on their patients&#8217; favorite apps. In this instance, they would skip step one and start by assessing the behavioral theory content of the apps using BTS. This would enable them to advise patients on the best use of preferred apps in supporting behavior change. Using this method, their library will most likely not contain the less popular emotion-focused and cognitive apps. Therefore, regardless of the method, we suggest that these apps be identified using the refined keyword searches described in step 1, for instance, the keywords &#34;GI,&#34; &#34;glycemic index,&#34; &#34;relaxation,&#34; &#34;confidence,&#34; and &#34;CBT.&#34;</p>
                <p>Limitations of the study include the adoption of a relatively general app selection approach that used popularity as a key criterion. Information quality was assessed through professional opinion rather than through a more stringent set of criteria which could not be located at the time. Recently, a comprehensive tool for assessing app quality has been published&#8212;the Mobile App Rating Scale [<xref ref-type="bibr" rid="ref21">21</xref>]. Integration of this tool into the app selection step may increase the quality of the apps included in the library.</p>
            </sec>
            <sec>
                <title>Conclusions</title>
                <p>The potential for health apps to support the management of chronic disease is considerable. Health professionals are well positioned to guide patients in the most effective use of apps to meet their needs. Apps are rapidly evolving, so health professionals need to be vigilant and continuously assess apps and refine selection tools for matching apps with therapy. High-quality health apps may be handy instruments for the modern health practitioner&#8217;s toolbox.</p>
            </sec>
        </sec>
    </body>
    <back>
        <glossary>
            <title>Abbreviations</title>
            <def-list>
                <def-item>
                    <term id="abb1">B</term>
                    <def>
                        <p>behavioral</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb2">BTS</term>
                    <def>
                        <p>Behavioral Theory Content Survey</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb3">C</term>
                    <def>
                        <p>cognitive</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb4">CBT</term>
                    <def>
                        <p>cognitive behavioral therapy</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb5">CDSM</term>
                    <def>
                        <p>chronic disease self-management</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb6">EF</term>
                    <def>
                        <p>emotion focused</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb7">GI</term>
                    <def>
                        <p>glycemic index</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb8">HBM</term>
                    <def>
                        <p>Health Belief Model</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb9">K</term>
                    <def>
                        <p>knowledge</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb10">SCT</term>
                    <def>
                        <p>Social Cognitive Theory</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb11">SI</term>
                    <def>
                        <p>International System of Units</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb12">SMS</term>
                    <def>
                        <p>short message service</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb13">T</term>
                    <def>
                        <p>therapeutic</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb14">TGA</term>
                    <def>
                        <p>Therapeutic Goods Administration</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb15">TPB</term>
                    <def>
                        <p>Theory of Planned Behavior</p>
                    </def>
                </def-item>
                <def-item>
                    <term id="abb16">TTM</term>
                    <def>
                        <p>Transtheoretical Model</p>
                    </def>
                </def-item>
            </def-list>
        </glossary>
        <ack>
            <p>The primary author (KH) is supported by a commonwealth-funded scholarship.</p>
        </ack>
        <fn-group>
            <fn fn-type="con">
                <p>KH was the chief investigator primarily responsible for study conception and design, data analysis, and primary authorship on the manuscript. SC assisted with study design, data interpretation, and writing of the manuscript. JB assisted with study design. All authors critically reviewed the manuscript and approved the final version submitted for publication.</p>
            </fn>
            <fn fn-type="conflict">
                <p>None declared.</p>
            </fn>
        </fn-group>
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