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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMU</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIR Mhealth Uhealth</journal-id>
      <journal-title>JMIR mHealth and uHealth</journal-title>
      <issn pub-type="epub">2291-5222</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
    <article-id pub-id-type="publisher-id">v6i9e10799</article-id>
    <article-id pub-id-type="pmid">30224335</article-id>
    <article-id pub-id-type="doi">10.2196/10799</article-id>
    <article-categories>
      <subj-group subj-group-type="heading">
        <subject>Review</subject>
      </subj-group>
      <subj-group subj-group-type="article-type">
        <subject>Review</subject>
      </subj-group>
    </article-categories>
    <title-group>
      <article-title>Text Messaging Interventions for Improvement in Physical Activity and Sedentary Behavior in Youth: Systematic Review</article-title>
    </title-group>
    <contrib-group>
      <contrib contrib-type="editor">
        <name>
          <surname>Eysenbach</surname>
          <given-names>Gunther</given-names>
        </name>
      </contrib>
    </contrib-group>
    <contrib-group>
      <contrib contrib-type="reviewer">
        <name>
          <surname>Mitchell</surname>
          <given-names>Fiona</given-names>
        </name>
      </contrib>
      <contrib contrib-type="reviewer">
        <name>
          <surname>Cushing</surname>
          <given-names>Christopher</given-names>
        </name>
      </contrib>
      <contrib contrib-type="reviewer">
        <name>
          <surname>Kok</surname>
          <given-names>Gerjo</given-names>
        </name>
      </contrib>
    </contrib-group>
    <contrib-group>
      <contrib contrib-type="author" id="contrib1">
        <name name-style="western">
          <surname>Ludwig</surname>
          <given-names>Kim</given-names>
        </name>
        <degrees>MSc</degrees>
        <xref rid="aff1" ref-type="aff">1</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0001-9776-9606</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib2">
        <name name-style="western">
          <surname>Arthur</surname>
          <given-names>Rosie</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff1" ref-type="aff">1</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0003-0651-4056</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib3">
        <name name-style="western">
          <surname>Sculthorpe</surname>
          <given-names>Nicholas</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff1" ref-type="aff">1</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0001-8235-8580</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib4">
        <name name-style="western">
          <surname>Fountain</surname>
          <given-names>Hollie</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff2" ref-type="aff">2</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0001-9369-2322</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib5" corresp="yes">
      <name name-style="western">
        <surname>Buchan</surname>
        <given-names>Duncan S</given-names>
      </name>
      <degrees>PhD</degrees>
      <xref rid="aff1" ref-type="aff">1</xref>
      <address>
        <institution>Institute of Clinical Exercise and Health Science</institution>
        <institution>School of Health and Life Sciences</institution>
        <institution>University of the West of Scotland</institution>
        <addr-line>Stephenson Place</addr-line>
        <addr-line>Hamilton International Technology Park</addr-line>
        <addr-line>Blantyre, G72 0LH</addr-line>
        <country>United Kingdom</country>
        <phone>44 1698 283100 ext 8508</phone>
        <email>duncan.buchan@uws.ac.uk</email>
      </address>  
      <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-4320-4615</ext-link></contrib>
    </contrib-group>
    <aff id="aff1">
    <label>1</label>
    <institution>Institute of Clinical Exercise and Health Science</institution>
    <institution>School of Health and Life Sciences</institution>  
    <institution>University of the West of Scotland</institution>  
    <addr-line>Blantyre</addr-line>
    <country>United Kingdom</country></aff>
    <aff id="aff2">
    <label>2</label>
    <institution>School of Applied Sciences</institution>
    <institution>Edinburgh Napier University</institution>  
    <addr-line>Edinburgh</addr-line>
    <country>United Kingdom</country></aff>
    <author-notes>
      <corresp>Corresponding Author: Duncan S Buchan 
      <email>duncan.buchan@uws.ac.uk</email></corresp>
    </author-notes>
    <pub-date pub-type="collection"><month>09</month><year>2018</year></pub-date>
    <pub-date pub-type="epub">
      <day>17</day>
      <month>09</month>
      <year>2018</year>
    </pub-date>
    <volume>6</volume>
    <issue>9</issue>
    <elocation-id>e10799</elocation-id>
    <!--history from ojs - api-xml-->
    <history>
      <date date-type="received">
        <day>17</day>
        <month>4</month>
        <year>2018</year>
      </date>
      <date date-type="rev-request">
        <day>31</day>
        <month>5</month>
        <year>2018</year>
      </date>
      <date date-type="rev-recd">
        <day>13</day>
        <month>6</month>
        <year>2018</year>
      </date>
      <date date-type="accepted">
        <day>16</day>
        <month>6</month>
        <year>2018</year>
      </date>
    </history>
    <!--(c) the authors - correct author names and publication date here if necessary. Date in form ', dd.mm.yyyy' after jmir.org-->
    <copyright-statement>©Kim Ludwig, Rosie Arthur, Nicholas Sculthorpe, Hollie Fountain, Duncan S Buchan. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 17.09.2018.</copyright-statement>
    <copyright-year>2018</copyright-year>
    <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
      <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR mhealth and uhealth, is properly cited. The complete bibliographic information, a link to the original publication on http://mhealth.jmir.org/, as well as this copyright and license information must be included.</p>
    </license>  
    <self-uri xlink:href="http://mhealth.jmir.org/2018/9/e10799/" xlink:type="simple"/>
    <abstract>
      <sec sec-type="background">
        <title>Background</title>
        <p>The use of text messages (short message service, SMS) to change physical activity and sedentary behavior in youth is of interest due to the need for novel, more effective intervention approaches. Previous reviews have examined a variety of technology-based interventions and their impact on different health behaviors, but evidence regarding the impact of just SMS on physical activity and sedentary behavior is lacking.</p>
      </sec>
      <sec sec-type="objective">
        <title>Objective</title>
        <p>The aim of this study was to assess the effectiveness and use of theory of SMS interventions for improving physical activity and sedentary behavior in youth.</p>
      </sec>
      <sec sec-type="methods">
        <title>Methods</title>
        <p>Authors systematically searched electronic databases from March to November 2017. Citations were sifted using additional reviewers, and a qualitative synthesis of eligible studies was conducted using piloted data extraction forms. To be eligible for inclusion, studies had to be of a randomized controlled or quasi-experimental design, incorporate SMS, involve adolescents between the ages of 10 and 19 years, and assess at least one physical activity or sedentary behavior outcome. Risk of bias was assessed using the Cochrane Collaboration’s Risk of Bias tool.</p>
      </sec>
      <sec sec-type="results">
        <title>Results</title>
        <p>A total of 13 studies reporting 11 interventions were included in the qualitative analysis. Studies included interventions that were conducted in schools, online, or face-to-face. Studies were of high heterogeneity with regard to study duration, participant characteristics, intervention content, and outcome measures. Findings were equivocal with regard to intervention effectiveness for physical activity and sedentary behavior. Overall, 7 interventions resulted in an improvement for physical activity and 6 for sedentary behavior. All studies were judged to be of high risk of bias for at least 1 item.</p>
      </sec>
      <sec sec-type="conclusions">
        <title>Conclusions</title>
        <p>Some studies in this review showed promising results for using SMS to improve physical activity and sedentary behavior in youth. High heterogeneity of design and outcome measures precluded data pooling and conclusions as to which specific intervention elements are linked to increased effectiveness cannot be drawn. The authors propose incorporating the following elements in future studies: specific focus on desired health behavior; mixed-methods design; include long-term follow-up; include self-monitoring, goal setting, and feedback; combine SMS with a mobile app; and send 3 or more SMS text messages per week. More rigorous studies are needed to explore the relationship between intervention effectiveness and specific intervention components such as content and delivery.</p>
      </sec>
    </abstract>
    <kwd-group>
      <kwd>review</kwd>
      <kwd>exercise</kwd>
      <kwd>sedentary lifestyle</kwd>
      <kwd>text messaging</kwd>
      <kwd>cell phone</kwd>
      <kwd>telemedicine</kwd>
      <kwd>adolescent</kwd>
    </kwd-group></article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <sec>
        <title>Physical Activity and Sedentary Behavior</title>
        <p>Participating in sufficient levels of physical activity (PA) is essential to reduce the risk of all-cause mortality and cardiovascular disease [<xref ref-type="bibr" rid="ref1">1</xref>,<xref ref-type="bibr" rid="ref2">2</xref>]. For adolescents, it is recommended that they undertake at least 60 min of moderate to vigorous PA (MVPA) per day [<xref ref-type="bibr" rid="ref3">3</xref>]. Unfortunately, few adhere to these current activity recommendations with adolescence characterized by declining PA levels in conjunction with increased sedentary time, despite calls for sedentary time to be minimized [<xref ref-type="bibr" rid="ref4">4</xref>]. For instance, findings from Europe suggest that 83.2% of the adolescents aged 11 to 17 years do not achieve a minimum of 60 min of MVPA per day, whereas globally, it has been estimated that 80.3% of adolescents are insufficiently active [<xref ref-type="bibr" rid="ref5">5</xref>]. Moreover, global data suggest that adolescents spend 57% of their time in sedentary activities, with 40% of adolescents spending 3 or more hours watching television on weekdays, increasing up to 50% on weekends [<xref ref-type="bibr" rid="ref6">6</xref>,<xref ref-type="bibr" rid="ref7">7</xref>]. These findings are particularly concerning as sedentary behavior (SB) is associated with various aspects of poor psychological and physiological health and all-cause and cardiovascular disease-related mortality [<xref ref-type="bibr" rid="ref8">8</xref>-<xref ref-type="bibr" rid="ref11">11</xref>]. Conversely, increased PA improves adiposity, blood lipid profile, blood pressure, insulin resistance, aerobic fitness, and bone health [<xref ref-type="bibr" rid="ref12">12</xref>] while also reducing premature all-cause mortality [<xref ref-type="bibr" rid="ref13">13</xref>]. Given these relationships, both SB and PA are important therapeutic targets to reduce lifestyle-induced noncommunicable diseases and especially during adolescence, as behaviors developed in younger ages are likely to continue into later life [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref15">15</xref>]. Given the inconsistent success of traditional intervention approaches, there is a need for research to generate new strategies to modify physical inactivity and SB [<xref ref-type="bibr" rid="ref16">16</xref>].</p>
      </sec>
      <sec>
        <title>Mobile Health</title>
        <p>Mobile health (mHealth) which draws upon mobile devices for health-related apps has emerged as a promising tool for health-related behavioral interventions [<xref ref-type="bibr" rid="ref17">17</xref>]. Mobile phones are used by all age groups, with more than 90% of UK children aged 12 to 15 years currently using them [<xref ref-type="bibr" rid="ref18">18</xref>]. Such high usage suggests that these mobile devices may offer a cost-effective and acceptable means for delivering health behavior change interventions that can fit within people’s everyday lives and have population-wide reach. Unsurprisingly, mHealth approaches are also being used to provide health care services worldwide, including Africa, Asia, and South America [<xref ref-type="bibr" rid="ref19">19</xref>]. In the United Kingdom, the National Health Service is employing the SMS (short message service) text messaging system Florence to support patients in monitoring, managing, and improving their health [<xref ref-type="bibr" rid="ref20">20</xref>]. mHealth systems can also be used to send appointment or medication reminders to support health care workers by providing training, decision making, and communication tools as well as to implement health promotion and educational interventions [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref21">21</xref>]. However, there is a lack of evidence regarding the effectiveness of mHealth interventions on behavior changes and health outcomes [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref23">23</xref>]. Unfortunately, research that has examined the effects of SMS interventions on PA and SB in youth is also scant.</p>
        <p>Previous systematic reviews and meta-analyses involving adolescents have included a variety of technologies, such as apps, email, video games, and websites when reviewing the evidence on the most effective means of improving PA and SB [<xref ref-type="bibr" rid="ref24">24</xref>-<xref ref-type="bibr" rid="ref32">32</xref>]. However, none of these reviews have assessed the effectiveness of SMS in isolation. Moreover, reviews have included a number of outcomes such as disease state or medication adherence [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref33">33</xref>-<xref ref-type="bibr" rid="ref36">36</xref>] and have focused on several different health behaviors, such as smoking and diet [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref29">29</xref>-<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref34">34</xref>]. As such, evidence that has examined the efficacy of mobile devices to influence PA and SB is lacking. Furthermore, and to the best of our knowledge, existing systematic reviews and meta-analyses involving adolescents and SMS as a means for improving PA and SB have not explored the use of theoretical frameworks [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref30">30</xref>-<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref34">34</xref>-<xref ref-type="bibr" rid="ref37">37</xref>].</p>
      </sec>
      <sec>
        <title>Theoretical Frameworks</title>
        <p>As evidence has shown the increased effectiveness of health interventions using a behavioral theory framework [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>], it is surprising that many interventions have been developed without a proper underpinning theory. Even in those studies that suggest their intervention was informed by appropriate theory, the specific application of theory often remains unclear [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref41">41</xref>]. In addition to evaluating the evidence of the effectiveness of interventions using mobile phones for improving PA and SB, it is important to evaluate the theory and behavior change techniques (BCTs) that have been used to develop these interventions. Providing this information is essential for health care practitioners to ensure that future mHealth interventions are effectively implemented.</p>
      </sec>
      <sec>
        <title>Aims</title>
        <p>To provide this evidence, this review aimed to systematically identify mHealth studies that have been developed to increase PA levels and to reduce SB in adolescents. A subsequent aim was to identify the theory and BCTs used in these studies. Findings from this review are expected to provide an insight into the development of future mHealth interventions to maximize their effectiveness.</p>
      </sec>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Data Reporting</title>
        <p>All data are reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement guidelines [<xref ref-type="bibr" rid="ref42">42</xref>].</p>
      </sec>
      <sec>
        <title>Eligibility Criteria</title>
        <p>Experimental (randomized controlled trial or quasi-experimental design) studies were included if they involved or reported data separately for participants between the ages of 10 and 19 years with or without known morbidities; used SMS via a mobile phone within the intervention, both in addition to other intervention components or on its own; employed usual care, another intervention, or no intervention as comparator; and assessed at least one outcome related to PA or SB. All outcomes related to PA and SB, such as step count, moderate PA (MPA), and screen time, as well as all subjective and objective outcome measures were eligible for inclusion.</p>        <p>Furthermore, only studies that were written in the English language and where full text was available were included. Studies were excluded if they solely used other technologies such as apps, websites, or email.</p>
      </sec>
      <sec>
        <title>Information Sources</title>
        <p>A systematic search of the following electronic databases was conducted in March 2017 and updated in November 2017: Web of Science (coverage 1864-2017), PubMed (1809-2017), MEDLINE (1946-2017), Cumulative Index to Nursing and Allied Health Literature Complete (1937-2017), PsycINFO (1800s-2017; not available for search update and replaced by PsycARTICLES 1894-2017), and SPORTDiscus (1930-2017). All databases except PubMed (November 7, 2017) were last searched on November 8, 2017. During the initial search, KL searched bibliographies and contacted corresponding authors of eligible studies. Bibliographies of existing systematic reviews and meta-analyses identified during the initial search process were also screened for eligible studies [<xref ref-type="bibr" rid="ref24">24</xref>-<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref44">44</xref>].</p>
      </sec>
      <sec>
        <title>Search</title>
        <p>Search terms and combinations of the electronic database search are shown in <xref ref-type="table" rid="table1">Table 1</xref>.</p>
      </sec>
      <sec>
        <title>Study Selection</title>
        <p>Study citations from the electronic search were imported into the reference manager software Zotero (Version 5.0, online and standalone). KL manually removed duplicates. For the initial search, KL and HF independently screened titles and abstracts of all remaining studies. Following the search update, KL and DSB independently reviewed new titles and abstracts with the full texts of relevant titles obtained to confirm eligibility. KL and HF (DSB for search update) discussed discrepancies until consensus was reached. KL hand-searched bibliographies of eligible studies and contacted corresponding authors for additional manuscripts. All eligible studies were then included in the qualitative analysis.</p>
      </sec>
      <sec>
        <title>Data Collection Process</title>
        <p>Data extraction was conducted based on the Cochrane Collaboration’s Data Extraction Template for Included Studies (Version 1.8) [<xref ref-type="bibr" rid="ref45">45</xref>]. Items of interest for this review such as the content of SMS and interactivity were added to the Cochrane Data Extraction Template. KL piloted the updated template on 2 randomly chosen studies eligible for this review. Subsequently, the piloted form was revised where necessary. Thereafter, KL and HF (DSB after search update) independently extracted required data using the revised form. Extractions were compared and discussed until consensus was reached for all items. Content was then synthesized for analysis.</p>
      </sec>
      <sec>
        <title>Data Items</title>
        <p>Data extracted included (1) general study information (such as country, aims, and target health behavior); (2) methods (such as study design and duration of intervention); (3) participants (such as population description, number recruited, age, sex, and health status); (4) intervention and control groups (such as name of group, number of participants randomized, intervention mode, content, use of theory, message content, frequency, device, interaction, and adherence); (5) outcomes (assessed PA and SB outcomes, method of PA/SB outcome assessment, timing of PA/SB outcome assessment); (6) results and conclusion (including additional results information and relevant conclusions); (7) other information (including funding source and conflicts of interest). Where data were missing or clarification was sought, study authors were contacted. Where multiple studies reported on multiple follow-up periods or outcomes of the same intervention, outcomes from the longest follow-up time point available for each outcome were extracted.</p>
      </sec>
      <sec>
        <title>Risk of Bias in Individual Studies</title>
        <p>Assessment of risk of bias was conducted at study level. KL and HF (DSB after search update) reviewed all included manuscripts using the Cochrane Collaboration’s risk of bias assessment tool [<xref ref-type="bibr" rid="ref46">46</xref>]. KL employed this assessment tool using RevMan (software, version 5.3). Due to the nature of behavioral interventions, blinding of participants and personnel is challenging and rarely incorporated [<xref ref-type="bibr" rid="ref47">47</xref>]. This item was therefore not included in the assessment. The following remaining domains were judged: selection bias (random sequence allocation and allocation concealment), detection bias (blinding of outcome assessment), attrition bias (incomplete outcome data), reporting bias (selective reporting), and other bias. KL and HF (DSB after search update) ranked each item as high, low, or unclear risk for each study and discussed discrepancies until a consensus was reached.</p>
        
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Electronic database search terms and combinations. Asterisks were used to search for words beginning with these letters.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="620"/>
            <col width="350"/>
            <thead>
              <tr valign="top">
                <td colspan="2">Category</td>
                <td>Search term</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="2"><bold>Intervention mode</bold></td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>1</td>
                <td>“mobile phone”</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>2</td>
                <td>smartphone</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>3</td>
                <td>“cell phone”</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>4</td>
                <td>“handheld device”</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>5</td>
                <td>text messag*</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>6</td>
                <td>SMS<sup>a</sup></td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>7</td>
                <td>“messag* service”</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>8</td>
                <td>“messaging system”</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>9</td>
                <td>mHealth</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>10</td>
                <td>telehealth</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>11</td>
                <td>“online health”</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>12</td>
                <td>e-Health</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>13</td>
                <td>eHealth</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>14</td>
                <td>“mobile health”</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>15</td>
                <td>“digital media”</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>16</td>
                <td>ICT<sup>b</sup></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>17</td>
                <td>(1-16) combined with OR</td>
              </tr>
              <tr valign="top">
                <td colspan="2"><bold>Study design</bold></td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>18</td>
                <td>“randomised controlled”</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>19</td>
                <td>“randomized controlled”</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>20</td>
                <td>RCT<sup>d</sup></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>21</td>
                <td>“controlled trial”</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>22</td>
                <td>quasi-experimental</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>23</td>
                <td>(18-22) combined with OR</td>
              </tr>
              <tr valign="top">
                <td colspan="2"><bold>Participants</bold></td>
                <td><break/></td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>24</td>
                <td>adolescen*</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>25</td>
                <td>youth</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>26</td>
                <td>“young people”</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>27</td>
                <td>“young adult*”</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>28</td>
                <td>child*</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>29</td>
                <td>paediatric</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>30</td>
                <td>pediatric</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>31</td>
                <td>teen*</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>32</td>
                <td>“school age”</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>33</td>
                <td>“school-aged”</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>34</td>
                <td>highschool</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>35</td>
                <td>“secondary school”</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>36</td>
                <td>(24-35) combined with OR</td>
              </tr>
              <tr valign="top">
                <td colspan="2"><bold>Behavior</bold></td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>37</td>
                <td>activity</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>38</td>
                <td>sport</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>39</td>
                <td>exercise</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>40</td>
                <td>health*</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>41</td>
                <td>“behaviour change”</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>42</td>
                <td>lifestyle</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>43</td>
                <td>sedentary</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>44</td>
                <td>sitting</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>45</td>
                <td>(37-44) combined with OR</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>46</td>
                <td>(17,23,36,45) combined with AND</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table1fn1">
              <p><sup>a</sup>SMS: short message service.</p>
            </fn>
            <fn id="table1fn2">
              <p><sup>b</sup>ICT: information and communication technology.</p>
            </fn>
            <fn id="table1fn3">
              <p><sup>c</sup>RCT: randomized controlled trial.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>

      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <sec>
        <title>Study Selection</title>
        <p>The electronic database and hand search produced 5565 and 266 studies, respectively. After removal of duplicates, 2365 studies were screened. A total of 2295 records were excluded, and 70 full-text articles were assessed. Moreover, 13 eligible full-text articles assessing 11 different interventions remained and were included in the qualitative analysis. A flowchart of the systematic literature search is displayed in <xref ref-type="fig" rid="figure1">Figure 1</xref>.</p>
      </sec>
      <sec>
        <title>Study Characteristics</title>
        <p>Study characteristics of included studies are shown in <xref ref-type="table" rid="table2">Tables 2</xref> and <xref ref-type="table" rid="table3">3</xref>. A total of 12 studies targeted PA [<xref ref-type="bibr" rid="ref48">48</xref>-<xref ref-type="bibr" rid="ref59">59</xref>] and 7 targeted SB [<xref ref-type="bibr" rid="ref48">48</xref>-<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref59">59</xref>,<xref ref-type="bibr" rid="ref60">60</xref>]. Additionally, most studies also focused on dietary behaviors [<xref ref-type="bibr" rid="ref49">49</xref>-<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref59">59</xref>,<xref ref-type="bibr" rid="ref60">60</xref>].</p>
        <p>Some studies focused on participants with specific characteristics, including those not meeting current PA guidelines [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref53">53</xref>], not participating in physical education lessons or organized sports [<xref ref-type="bibr" rid="ref54">54</xref>], having type 1 diabetes [<xref ref-type="bibr" rid="ref56">56</xref>], being at high risk for diabetes [<xref ref-type="bibr" rid="ref57">57</xref>], having a body mass index ≥ the eighty-fifth percentile [<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref59">59</xref>], and being ≥1 year post cancer therapy [<xref ref-type="bibr" rid="ref55">55</xref>]. When including overweight or obese participants, rates ranged between 23.7% (62/262) [<xref ref-type="bibr" rid="ref52">52</xref>] and 55% (22/40) [<xref ref-type="bibr" rid="ref49">49</xref>] for overweight and between 6.7% (15/225) [<xref ref-type="bibr" rid="ref52">52</xref>] and 45% (18/40) [<xref ref-type="bibr" rid="ref49">49</xref>] for obesity. The mean age of participants ranged between 12.5 [<xref ref-type="bibr" rid="ref52">52</xref>] and 17.3 years [<xref ref-type="bibr" rid="ref58">58</xref>]. One intervention only included female participants [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref54">54</xref>]. A total of 12 studies consisted of ≥50% female participants [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref50">50</xref>-<xref ref-type="bibr" rid="ref60">60</xref>].</p>
      </sec>
      <sec>
        <title>Intervention Design and Content</title>
        <p>A total of 2 interventions included SMS in addition to a school program [<xref ref-type="bibr" rid="ref50">50</xref>-<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref54">54</xref>]. A total of 5 interventions used SMS text messages as part of an online intervention [<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref60">60</xref>] and others used pedometers [<xref ref-type="bibr" rid="ref56">56</xref>], group sessions and telephone calls [<xref ref-type="bibr" rid="ref59">59</xref>], apps [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref55">55</xref>], and Fitbit trackers (Fitbit, Inc.) [<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref55">55</xref>]. Only one intervention consisted solely of SMS [<xref ref-type="bibr" rid="ref58">58</xref>]. Moreover, 2 interventions consisted of different types of SMS [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref58">58</xref>]. Depending on group allocation, one employed SMS focusing on affective or instrumental beliefs [<xref ref-type="bibr" rid="ref58">58</xref>], whereas the other involved SMS from different senders, including a parent, peer, or behavioral health specialist [<xref ref-type="bibr" rid="ref48">48</xref>]. School-based interventions using SMS included elements such as sports and PA opportunities, educational (group) seminars, provision of healthy foods, self-monitoring tools, and printed or email materials promoting healthy lifestyles [<xref ref-type="bibr" rid="ref50">50</xref>-<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref54">54</xref>]. One intervention also used a Facebook group to promote healthy lifestyles and keep participants informed about the intervention [<xref ref-type="bibr" rid="ref52">52</xref>]. Interventions that included an online component also consisted of a variety of elements, such as forums, diet analysis, videos, educational games, challenges, educational materials, expert advice, behavioral skill training, goal setting, monitoring, feedback, and tutorials on behavioral change strategies [<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref60">60</xref>]. One study included access to a private Facebook group, which provided rewards for achievements, encouragement, and a discussion board, as well as using Fitbit trackers and an app to monitor progress toward individualized goals [<xref ref-type="bibr" rid="ref55">55</xref>].</p>
        <p>In another study, participants wore pedometers that were used to encourage PA and facilitate recording progress [<xref ref-type="bibr" rid="ref56">56</xref>]. Another study included group sessions that provided education on health behaviors and achieving successful behavior change. In this study, participants also received phone coaching during the 12-month maintenance period post intervention [<xref ref-type="bibr" rid="ref59">59</xref>]. One study using an app for monitoring and reporting of PA also included autonomous and external goal setting as well as daily feedback [<xref ref-type="bibr" rid="ref48">48</xref>]. Depending on which condition participants were assigned for that day, SMS text messages were sent by a behavioral health specialist, parents, or a peer [<xref ref-type="bibr" rid="ref48">48</xref>].</p>
      </sec>
      <sec>
        <title>Content of Text Messages</title>
        <p>SMS text messages were used to encourage, motivate, reinforce, and prompt participants to be physically active or maintain their current positive behavior changes [<xref ref-type="bibr" rid="ref48">48</xref>-<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>-<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref59">59</xref>,<xref ref-type="bibr" rid="ref60">60</xref>]. Some studies provided participants with suggestions for healthy lifestyle behaviors [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref59">59</xref>].</p>
        
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>Literature search flow chart.</p>
          </caption>
          <graphic xlink:href="mhealth_v6i9e10799_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
        
                <p>In addition to promoting PA, one study also employed SMS to provide participants with health behavior information, behavioral skills, and solutions for PA barriers to reinforce the benefits of PA and to build rapport with a virtual friend [<xref ref-type="bibr" rid="ref53">53</xref>]. SMS text messages were also used for feedback [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref53">53</xref>], which in one study depended on the participant’s goal attainment [<xref ref-type="bibr" rid="ref48">48</xref>]. SMS also included statements from testimonials as well as messages targeting intrinsic motivation and reflective questioning [<xref ref-type="bibr" rid="ref59">59</xref>]. SMS text messages were also used to reduce risk behaviors [<xref ref-type="bibr" rid="ref60">60</xref>]. Two interventions employed SMS aiming to increase participant self-efficacy [<xref ref-type="bibr" rid="ref59">59</xref>,<xref ref-type="bibr" rid="ref60">60</xref>]. Three interventions sent SMS related to goal-setting, such as the participants’ specific weekly challenges [<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref59">59</xref>]. In addition to this, one intervention included affective SMS for encouragement and as a reminder of PA goals. In this intervention, SMS text messages sent in intervention week 2 were based on the participants’ step counts from week 1 [<xref ref-type="bibr" rid="ref55">55</xref>]. Another study sent SMS text messages regarding affective or, depending on the intervention group, instrumental gains associated with regular PA. These include messages regarding the benefits of being active, such as physical and psychological improvements [<xref ref-type="bibr" rid="ref58">58</xref>]. Three studies used SMS text messages to remind participants to follow the intervention protocol, such as logging on to the intervention website or wearing an activity tracker [<xref ref-type="bibr" rid="ref49">49</xref>-<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref57">57</xref>].</p>
      </sec>
      <sec>
        <title>Theory Derivation</title>
        <p>Three studies based their interventions on the transtheoretical model (TTM) of behavior change or stage of motivational readiness for change (SOC) model [<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref60">60</xref>]. One study used the SOC model to tailor intervention content and presentation, such as by adapting TM and website content according to the participant’s stage of motivational readiness [<xref ref-type="bibr" rid="ref53">53</xref>]. Participants in precontemplation, contemplation, and preparation stage were given information on benefits and barriers of PA, opportunities for PA, goal setting, as well as PA planning. Participants classed in the action stage were provided with monitoring tools and information to prevent relapse [<xref ref-type="bibr" rid="ref53">53</xref>]. In addition to the TTM, one study also used the I-Change, Attitude-Social Influence-Self-Efficacy model and addressed attitude, social influence, and self-efficacy. They emphasized the advantages of following the recommendations and disadvantages of risk behaviors, created a healthy online social environment, and strengthened skills to avoid risk behaviors [<xref ref-type="bibr" rid="ref60">60</xref>].</p>
        
        <table-wrap position="float" id="table2">
          <label>Table 2</label>
          <caption>
            <p>Study characteristics of included studies—sample and outcomes.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="270"/>
            <col width="60"/>
            <col width="130"/>
            <col width="130"/>
            <col width="230"/>
            <col width="200"/>
            <thead>
              <tr valign="bottom">
                <td>Author, year, country</td>
                <td>N<sup>a</sup></td>
                <td>Design</td>
                <td>Age, mean (SD)</td>
                <td>PA<sup>b</sup> and SB<sup>c</sup> outcomes</td>
                <td>Assessment</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Brannon et al, 2017, United States [<xref ref-type="bibr" rid="ref48">48</xref>]</td>
                <td>10</td>
                <td>N-of-1 RCT<sup>d</sup></td>
                <td>16.7 (0.95)</td>
                <td>MVPA<sup>e</sup> min/day, SB min/day</td>
                <td>Objective</td>
              </tr>
              <tr valign="top">
                <td>Chen et al, 2017, United States [<xref ref-type="bibr" rid="ref49">49</xref>]</td>
                <td>40</td>
                <td>RCT</td>
                <td>14.9 (1.7)</td>
                <td>PA days/week, TV/computer hours/day</td>
                <td>Self-report</td>
              </tr>
              <tr valign="top">
                <td>Dewar et al, 2013, Australia [<xref ref-type="bibr" rid="ref50">50</xref>]</td>
                <td>357</td>
                <td>Group RCT</td>
                <td>13.2 (0.5)</td>
                <td>Accelerometer counts/min, % MVPA, screen time min/day</td>
                <td>PA: objective; SB: self-report</td>
              </tr>
              <tr valign="top">
                <td>Dewar et al, 2014, Australia [<xref ref-type="bibr" rid="ref51">51</xref>]</td>
                <td>357</td>
                <td>Group RCT</td>
                <td>13.2 (0.5)</td>
                <td>% MPA<sup>f</sup>, VPA<sup>g</sup>, MVPA; SB min/day</td>
                <td>PA: objective; SB: objective + self-report</td>
              </tr>
              <tr valign="top">
                <td>Ermetici et al, 2016, Italy [<xref ref-type="bibr" rid="ref52">52</xref>]</td>
                <td>487</td>
                <td>Nonrandomized CT<sup>h</sup></td>
                <td>12.5 (0.4)</td>
                <td>MVPA hours/week, screen time hours/day</td>
                <td>PA: objective + self-report; SB: self-report</td>
              </tr>
              <tr valign="top">
                <td>Lana et al, 2014, Spain and Mexico [<xref ref-type="bibr" rid="ref60">60</xref>]</td>
                <td>2001</td>
                <td>RCT</td>
                <td>Pre 13.26 (1.03); Post 12.91 (0.77)</td>
                <td>SB (less than 360 min PA/week)</td>
                <td>Self-report</td>
              </tr>
              <tr valign="top">
                <td>Lau et al, 2012, Hong Kong [<xref ref-type="bibr" rid="ref53">53</xref>]</td>
                <td>78</td>
                <td>Nonrandomized CT</td>
                <td>CG<sup>i</sup> 13.26 (1.14); IG<sup>j</sup> 12.29 (0.87)</td>
                <td>PA level last 7 days</td>
                <td>Self-report</td>
              </tr>
              <tr valign="top">
                <td>Lubans et al, 2012, Australia [<xref ref-type="bibr" rid="ref54">54</xref>]</td>
                <td>357</td>
                <td>Group RCT</td>
                <td>13.18 (0.45)</td>
                <td>Accelerometer counts/min, MVPA min/day, SB min/day</td>
                <td>PA: objective; SB: self-report</td>
              </tr>
              <tr valign="top">
                <td>Mendoza et al, 2017, United States [<xref ref-type="bibr" rid="ref55">55</xref>]</td>
                <td>60</td>
                <td>RCT</td>
                <td>16.6 (1.5)</td>
                <td>MVPA min/day, SB min/day</td>
                <td>Objective</td>
              </tr>
              <tr valign="top">
                <td>Newton et al, 2009, New Zealand [<xref ref-type="bibr" rid="ref56">56</xref>]</td>
                <td>78</td>
                <td>RCT</td>
                <td>14.4 (2.37)</td>
                <td>Step count, MVPA min/week</td>
                <td>Objective + self-report</td>
              </tr>
              <tr valign="top">
                <td>Patrick et al, 2013, United States [<xref ref-type="bibr" rid="ref57">57</xref>]</td>
                <td>101</td>
                <td>RCT</td>
                <td>14.3 (1.5)</td>
                <td>MVPA min/week, SB hours/day</td>
                <td>Self-report</td>
              </tr>
              <tr valign="top">
                <td>Sirriyeh et al, 2010, United Kingdom [<xref ref-type="bibr" rid="ref58">58</xref>]</td>
                <td>120</td>
                <td>RCT</td>
                <td>17.3 (0.68)</td>
                <td>MVPA metabolic equivalent min/week</td>
                <td>Self-report</td>
              </tr>
              <tr valign="top">
                <td>Straker et al, 2014, Australia [<xref ref-type="bibr" rid="ref59">59</xref>]</td>
                <td>44</td>
                <td>Within-subject CT</td>
                <td>14.1 (1.6)</td>
                <td>SB, light, moderate, vigorous PA min/day</td>
                <td>Objective</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table2fn1">
              <p><sup>a</sup>N: number of participants randomized.</p>
            </fn>
            <fn id="table2fn2">
              <p><sup>b</sup>PA: physical activity.</p>
            </fn>
            <fn id="table2fn3">
              <p><sup>c</sup>SB: sedentary behavior.</p>
            </fn>
            <fn id="table2fn4">
              <p><sup>d</sup>RCT: randomized controlled trial.</p>
            </fn>
            <fn id="table2fn5">
              <p><sup>e</sup>MVPA: moderate to vigorous physical activity.</p>
            </fn>
            <fn id="table2fn6">
              <p><sup>f</sup>MPA: moderate physical activity.</p>
            </fn>
            <fn id="table2fn7">
              <p><sup>g</sup>VPA: vigorous physical activity.</p>
            </fn>
            <fn id="table2fn8">
              <p><sup>h</sup>CT: controlled trial.</p>
            </fn>
            <fn id="table2fn9">
              <p><sup>i</sup>CG: control group.</p>
            </fn>
            <fn id="table2fn10">
              <p><sup>j</sup>IG: intervention group.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        
        <p>Moreover, one study used both behavioral determinants models and TTM to guide intervention design [<xref ref-type="bibr" rid="ref57">57</xref>]. One study employed affective and instrumental beliefs, as well as the theory of planned behavior (TPB) [<xref ref-type="bibr" rid="ref58">58</xref>]. Two interventions were informed by social cognitive theory (SCT) [<xref ref-type="bibr" rid="ref49">49</xref>-<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref54">54</xref>]. One focused on self-efficacy, outcome expectation, self-monitoring, skill mastery, and self-regulation capabilities [<xref ref-type="bibr" rid="ref49">49</xref>]. Another employed SCT by planning social support or change, providing general encouragement and information about the link between behavior and health, and identifying barriers and strategies to overcome these. Specifically, outcome expectations, social support, and self-efficacy were targeted [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref54">54</xref>]. Self-determination theory (SDT) formed the basis for 2 interventions [<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref59">59</xref>], with one also using goal-setting theory [<xref ref-type="bibr" rid="ref59">59</xref>]. This intervention focused on the provision of a need-supportive environment to achieve greater self-determination, autonomous motivation, and consequently greater engagement with the desired behaviors. The goal-setting theory was employed to increase autonomous and intrinsic goal setting to predict greater goal attainment and engagement with desired behaviors [<xref ref-type="bibr" rid="ref59">59</xref>]. The other focused on psychological needs that influence motivation such as competence, autonomy, and relatedness. The Fitbit tracker and app aimed to increase competence and autonomy by providing opportunities to set personalized goals and monitor progress. The Facebook group aimed to enhance relatedness by providing support [<xref ref-type="bibr" rid="ref55">55</xref>]. Cybernetic control theory (CCT) was used by one study, which included self-regulation strategies defined by goal-setting, self-monitoring, goal review, and feedback [<xref ref-type="bibr" rid="ref48">48</xref>]. Two studies did not provide any information regarding theory derivation. Authors were contacted and lack of a specific theory base informing SMS was confirmed [<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref56">56</xref>].</p>

        <table-wrap position="float" id="table3">
          <label>Table 3</label>
          <caption>
            <p>Study characteristics of included studies—intervention and comparator.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="200"/>
            <col width="170"/>
            <col width="330"/>
            <col width="300"/>
            <thead>
              <tr valign="bottom">
                <td>Author, year</td>
                <td>Intervention duration</td>
                <td>TM<sup>a</sup> intervention</td>
                <td>Comparators</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Brannon et al, 2017 [<xref ref-type="bibr" rid="ref48">48</xref>]</td>
                <td>24 days</td>
                <td>TM + mobile app</td>
                <td>Mobile app only</td>
              </tr>
              <tr valign="top">
                <td>Chen et al, 2017 [<xref ref-type="bibr" rid="ref49">49</xref>]</td>
                <td>6 months</td>
                <td>TM + Fitbit tracker and app + online program</td>
                <td>Online program + pedometer + diary</td>
              </tr>
              <tr valign="top">
                <td>Dewar et al, 2013 [<xref ref-type="bibr" rid="ref50">50</xref>]</td>
                <td>12 months</td>
                <td>TM + school program</td>
                <td>Waitlist condensed intervention</td>
              </tr>
              <tr valign="top">
                <td>Dewar et al, 2014 [<xref ref-type="bibr" rid="ref51">51</xref>]</td>
                <td>12 months</td>
                <td>TM + school program</td>
                <td>Waitlist condensed intervention</td>
              </tr>
              <tr valign="top">
                <td>Ermetici et al, 2016 [<xref ref-type="bibr" rid="ref52">52</xref>]</td>
                <td>24 months</td>
                <td>TM + school program</td>
                <td>No information</td>
              </tr>
              <tr valign="top">
                <td>Lana et al, 2014 [<xref ref-type="bibr" rid="ref60">60</xref>]</td>
                <td>9 months</td>
                <td>TM + online program</td>
                <td>Online intervention, limited access online intervention</td>
              </tr>
              <tr valign="top">
                <td>Lau et al, 2012 [<xref ref-type="bibr" rid="ref53">53</xref>]</td>
                <td>8 weeks</td>
                <td>TM + online program</td>
                <td>No intervention</td>
              </tr>
              <tr valign="top">
                <td>Lubans et al, 2012 [<xref ref-type="bibr" rid="ref54">54</xref>]</td>
                <td>12 months</td>
                <td>TM + school program</td>
                <td>Waitlist condensed intervention</td>
              </tr>
              <tr valign="top">
                <td>Mendoza et al, 2017 [<xref ref-type="bibr" rid="ref55">55</xref>]</td>
                <td>10 weeks</td>
                <td>TM + Fitbit tracker and app + Facebook group</td>
                <td>Standard care</td>
              </tr>
              <tr valign="top">
                <td>Newton et al, 2009 [<xref ref-type="bibr" rid="ref56">56</xref>]</td>
                <td>12 weeks</td>
                <td>TM + pedometer</td>
                <td>Standard care</td>
              </tr>
              <tr valign="top">
                <td>Patrick et al, 2013 [<xref ref-type="bibr" rid="ref57">57</xref>]</td>
                <td>12 months</td>
                <td>TM + online program</td>
                <td>Online program, online program + group sessions + phone calls, usual care</td>
              </tr>
              <tr valign="top">
                <td>Sirriyeh et al, 2010 [<xref ref-type="bibr" rid="ref58">58</xref>]</td>
                <td>2 weeks</td>
                <td>TM only</td>
                <td>Neutral TM</td>
              </tr>
              <tr valign="top">
                <td>Straker et al, 2014 [<xref ref-type="bibr" rid="ref59">59</xref>]</td>
                <td>12 months</td>
                <td>TM + group sessions + phone calls</td>
                <td>No intervention</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table3fn1">
              <p><sup>a</sup>TM: text messaging.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>

      </sec>
      <sec>
        <title>Text Message Delivery and Interactivity</title>
        <p>In 3 studies, SMS text messages were sent weekly [<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref60">60</xref>], 2 sent daily [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref58">58</xref>], another sent only on weekdays [<xref ref-type="bibr" rid="ref53">53</xref>], and 2 studies sent 3 or more each week [<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref57">57</xref>]. Two studies only sent SMS text messages during the maintenance period following the intervention [<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref59">59</xref>]. In one, the number of SMS text messages was reduced from 3 to 1 per week and finally to 1 per month [<xref ref-type="bibr" rid="ref59">59</xref>]. In the other, SMS text messages were sent biweekly during a 3-month maintenance phase [<xref ref-type="bibr" rid="ref49">49</xref>]. Another intervention increased the frequency of SMS from weekly to twice per week [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref54">54</xref>]. Five studies specified the time of SMS delivery [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref50">50</xref>-<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref59">59</xref>]. SMS text messages were sent at 4 pm at the end of the school day to minimize the risk of cross-contamination [<xref ref-type="bibr" rid="ref58">58</xref>], close to meal times [<xref ref-type="bibr" rid="ref52">52</xref>], between 7 pm and 8 pm [<xref ref-type="bibr" rid="ref48">48</xref>] and depending on the SMS content, such as immediately after school when encouraging PA [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref54">54</xref>]. Another study sent SMS on weekday evenings at 6 pm and at 12 pm on weekends. Here, participants were able to choose on which days they wished to receive the SMS [<xref ref-type="bibr" rid="ref59">59</xref>].</p>
        <p>Three studies gave participants the possibility to interact with the research team and reply to the SMS [<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref59">59</xref>]. Responding was optional; however, one study provided a monetary incentive to do so [<xref ref-type="bibr" rid="ref53">53</xref>]. Another study also allowed interactivity; however, participants would only receive one reply [<xref ref-type="bibr" rid="ref59">59</xref>].</p>
      </sec>
      <sec>
        <title>Risk of Bias Within Studies</title>
        <p>Five studies referred to previously published study protocols [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref59">59</xref>,<xref ref-type="bibr" rid="ref60">60</xref>]. These were used to obtain missing information needed for the risk of bias assessment. The judgment of each risk of bias item across studies can be found in <xref ref-type="fig" rid="figure2">Figure 2</xref>. <xref ref-type="table" rid="table4">Tables 4</xref> and <xref ref-type="table" rid="table5">5</xref> show the support for judgment of each item and study.</p>
              <p>Several studies were rated as unclear selection bias with regard to random sequence allocation [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref54">54</xref>-<xref ref-type="bibr" rid="ref57">57</xref>]. Three were rated high risk [<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref59">59</xref>], and 3 were rated low risk [<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref60">60</xref>]. Most studies also tended to be of unclear risk of selection bias with regard to allocation concealment [<xref ref-type="bibr" rid="ref48">48</xref>-<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>-<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref60">60</xref>]. Two studies were rated as high risk for this item [<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref59">59</xref>]. A total of 7 studies were ranked to be of unclear risk of detection bias [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref23">23</xref>-<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref30">30</xref>], with 4 judged as high-risk [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref59">59</xref>] and 2 as low-risk [<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref58">58</xref>]. With regards to attrition bias, 7 studies were judged to be of low risk [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>-<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref59">59</xref>], whereas 5 were ranked as unclear [<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref60">60</xref>] and one as high-risk [<xref ref-type="bibr" rid="ref48">48</xref>]. Twelve studies were of low risk of reporting bias [<xref ref-type="bibr" rid="ref48">48</xref>-<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref59">59</xref>,<xref ref-type="bibr" rid="ref60">60</xref>]. Only one study was classed as high risk of bias for this item [<xref ref-type="bibr" rid="ref58">58</xref>]. Ten studies were ranked as high risk of response and recall bias [<xref ref-type="bibr" rid="ref49">49</xref>-<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref56">56</xref>-<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref60">60</xref>]. Risk of compliance bias was evident in 3 studies [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref53">53</xref>]. Another study was judged to be of high risk of analytical bias [<xref ref-type="bibr" rid="ref58">58</xref>]. Two studies appeared free of other sources of bias [<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref59">59</xref>].</p>
      
      
  
      </sec>
      <sec>
        <title>Synthesis of Results</title>
        <p>PA and SB assessed in hours per week or hours per day were converted into min per week and min per day [<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref57">57</xref>]. For the following, intervention group refers to those involving SMS text messages. An overview of the findings including PA and SB outcomes and outcome measures can be found in <xref ref-type="table" rid="table6">Table 6</xref>. <xref ref-type="table" rid="table7">Table 7</xref> shows theoretical frameworks used and effectiveness of intervention groups in each study.</p>
        
          <fig id="figure2" position="float">
          <label>Figure 2</label>
          <caption>
            <p>Risk of bias assessment.</p>
          </caption>
          <graphic xlink:href="mhealth_v6i9e10799_fig2.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
        
        <table-wrap position="float" id="table4">
          <label>Table 4</label>
          <caption>
            <p>Support for judgment of risk of bias per item and study. Random sequence generation, allocation concealment, and blinding of outcome assessment.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="200"/>
            <col width="260"/>
            <col width="260"/>
            <col width="280"/>
            <thead>
              <tr valign="top">
                <td>Author, year</td>
                <td>Random sequence generation</td>
                <td>Allocation concealment</td>
                <td>Blinding of outcome assessment</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Brannon et al, 2017 [<xref ref-type="bibr" rid="ref48">48</xref>]</td>
                <td>Unclear; Not enough information</td>
                <td>Unclear; Not enough information</td>
                <td>Unclear; Not enough information</td>
              </tr>
              <tr valign="top">
                <td>Chen et al, 2017 [<xref ref-type="bibr" rid="ref49">49</xref>]</td>
                <td>Low; Randomization using computer program</td>
                <td>Unclear; Not enough information</td>
                <td>Unclear; Not enough information</td>
              </tr>
              <tr valign="top">
                <td>Dewar et al, 2013 [<xref ref-type="bibr" rid="ref50">50</xref>]</td>
                <td>Unclear; Not enough information</td>
                <td>Unclear; Not enough information</td>
                <td>High; At baseline only. Outcomes likely to be influenced by lack of blinding</td>
              </tr>
              <tr valign="top">
                <td>Dewar et al, 2014 [<xref ref-type="bibr" rid="ref51">51</xref>]</td>
                <td>Unclear; Not enough information</td>
                <td>Unclear; Not enough information</td>
                <td>Unclear; Not enough information</td>
              </tr>
              <tr valign="top">
                <td>Ermetici et al, 2016 [<xref ref-type="bibr" rid="ref52">52</xref>]</td>
                <td>High; No randomization</td>
                <td>High; No randomization</td>
                <td>Unclear; Not enough information</td>
              </tr>
              <tr valign="top">
                <td>Lana et al, 2014 [<xref ref-type="bibr" rid="ref60">60</xref>]</td>
                <td>Low; Randomization using computer program</td>
                <td>Unclear; Not enough information</td>
                <td>Unclear; Not enough information</td>
              </tr>
              <tr valign="top">
                <td>Lau et al, 2012 [<xref ref-type="bibr" rid="ref53">53</xref>]</td>
                <td>High; No randomization</td>
                <td>Unclear; Not enough information</td>
                <td>Unclear; Not enough information</td>
              </tr>
              <tr valign="top">
                <td>Lubans et al, 2012 [<xref ref-type="bibr" rid="ref54">54</xref>]</td>
                <td>Unclear; Not enough information</td>
                <td>Unclear; Not enough information</td>
                <td>High; At baseline only. Outcomes likely to be influenced by lack of blinding</td>
              </tr>
              <tr valign="bottom">
                <td>Mendoza et al, 2017 [<xref ref-type="bibr" rid="ref55">55</xref>]</td>
                <td>Unclear; Not enough information</td>
                <td>Unclear; Not enough information</td>
                <td>High; Unblinded RCT<sup>a</sup></td>
              </tr>
              <tr valign="top">
                <td>Newton et al, 2009 [<xref ref-type="bibr" rid="ref56">56</xref>]</td>
                <td>Unclear; Not enough information</td>
                <td>Unclear; Not enough information</td>
                <td>Low; Assessors blinded at follow-up</td>
              </tr>
              <tr valign="top">
                <td>Patrick et al, 2013 [<xref ref-type="bibr" rid="ref57">57</xref>]</td>
                <td>Unclear; Not enough information</td>
                <td>Unclear; Not enough information</td>
                <td>Unclear; Not enough information</td>
              </tr>
              <tr valign="top">
                <td>Sirriyeh et al, 2010 [<xref ref-type="bibr" rid="ref58">58</xref>]</td>
                <td>Low; Randomization using random number generator</td>
                <td>Unclear; Not enough information</td>
                <td>Low; Assessors blinded at follow-up</td>
              </tr>
              <tr valign="top">
                <td>Straker et al, 2014 [<xref ref-type="bibr" rid="ref59">59</xref>]</td>
                <td>High; Within-subject waitlist study design</td>
                <td>High; Within-subject waitlist study design</td>
                <td>High; Outcomes likely to be influenced by lack of blinding</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table4fn1">
              <p><sup>a</sup>RCT: randomized controlled trial.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        
      </sec>
      <sec>
        <title>Physical Activity</title>
        <p>Included studies assessed accelerometer counts [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref54">54</xref>], light PA [<xref ref-type="bibr" rid="ref59">59</xref>], moderate or vigorous PA [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref50">50</xref>-<xref ref-type="bibr" rid="ref59">59</xref>], step count [<xref ref-type="bibr" rid="ref56">56</xref>], or the number of days when a minimum of 60 min of PA was achieved [<xref ref-type="bibr" rid="ref49">49</xref>]. Nine studies assessed MVPA [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref52">52</xref>-<xref ref-type="bibr" rid="ref58">58</xref>]. Three studies resulted in a decrease between baseline and longest follow-up for the intervention group [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref57">57</xref>]. One study, however, found an increase in MVPA between 6- and 12-month assessment [<xref ref-type="bibr" rid="ref57">57</xref>]. In another study, MVPA of normal weight participants increased between baseline and 2-school-year follow-up for the intervention group, however, decreased for the control. For overweight or obese participants, MVPA increased in both groups [<xref ref-type="bibr" rid="ref52">52</xref>]. Four interventions resulted in increases in MVPA for all intervention and control groups between baseline and follow-up [<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref58">58</xref>]. Two studies assessing MVPA used different types of SMS [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref58">58</xref>]. TMs sent by parents were effective in increasing MVPA for 70% of participants, SMS sent by a peer for 50%, and those sent from a behavioral health specialist for 90% of participants. Overall, the intervention resulted in higher levels of PA than during the control condition [<xref ref-type="bibr" rid="ref48">48</xref>]. Another study employed neutral, affective, instrumental, or a combination of affective and instrumental SMS [<xref ref-type="bibr" rid="ref58">58</xref>]. Across all participants, MVPA increased during the 2-week intervention with affective SMS resulting in the highest levels of PA undertaken [<xref ref-type="bibr" rid="ref58">58</xref>]. In 2 studies, MPA and vigorous PA (VPA) were assessed [<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref59">59</xref>]. Total, during school, after school, and weekday MPA and VPA decreased from baseline to 12-week follow-up for both intervention and control group [<xref ref-type="bibr" rid="ref51">51</xref>]. The other study showed increases in MPA and VPA between baseline and 12 months [<xref ref-type="bibr" rid="ref59">59</xref>].</p>
        
          <table-wrap position="float" id="table5">
          <label>Table 5</label>
          <caption>
            <p>Support for judgment of risk of bias per item and study. Incomplete outcome data, reporting bias, and other bias.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="190"/>
            <col width="280"/>
            <col width="240"/>
            <col width="290"/>
            <thead>
              <tr valign="top">
                <td>Author, year</td>
                <td>Incomplete outcome data</td>
                <td>Reporting bias</td>
                <td>Other bias</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Brannon et al, 2017 [<xref ref-type="bibr" rid="ref48">48</xref>]</td>
                <td>High; High amount of missing data</td>
                <td>Low; All outcomes reported</td>
                <td>High; Compliance bias (use of incentives)</td>
              </tr>
              <tr valign="top">
                <td>Chen et al, 2017 [<xref ref-type="bibr" rid="ref49">49</xref>]</td>
                <td>Unclear; Insufficient reporting of reasons for missing data</td>
                <td>Low; All outcomes reported</td>
                <td>High; Response bias (use of self-report), compliance bias (use of rewards)</td>
              </tr>
              <tr valign="top">
                <td>Dewar et al, 2013 [<xref ref-type="bibr" rid="ref50">50</xref>]</td>
                <td>Low; Missing outcome data balanced and similar reasons across groups</td>
                <td>Low; All outcomes reported</td>
                <td>High; Response bias (use of self-report)</td>
              </tr>
              <tr valign="top">
                <td>Dewar et al, 2014 [<xref ref-type="bibr" rid="ref51">51</xref>]</td>
                <td>Low; Missing outcome data balanced and similar reasons across groups</td>
                <td>Low; All outcomes reported</td>
                <td>High; Response bias (use of self-report)</td>
              </tr>
              <tr valign="top">
                <td>Ermetici et al, 2016 [<xref ref-type="bibr" rid="ref52">52</xref>]</td>
                <td>Unclear; Insufficient reporting of reasons for missing data</td>
                <td>Low; All outcomes reported</td>
                <td>High; Response bias (use of self-report)</td>
              </tr>
              <tr valign="top">
                <td>Lana et al, 2014 [<xref ref-type="bibr" rid="ref60">60</xref>]</td>
                <td>Unclear; Insufficient reporting of attrition, exclusions, and reasons</td>
                <td>Low; All outcomes reported</td>
                <td>High; Response bias (use of self-report)</td>
              </tr>
              <tr valign="top">
                <td>Lau et al, 2012 [<xref ref-type="bibr" rid="ref53">53</xref>]</td>
                <td>Low; Missing outcome data balanced and similar reasons across groups</td>
                <td>Low; All outcomes reported</td>
                <td>High; Response bias (use of self-report), compliance bias (use of incentives)</td>
              </tr>
              <tr valign="top">
                <td>Lubans et al, 2012 [<xref ref-type="bibr" rid="ref54">54</xref>]</td>
                <td>Low; Missing outcome data balanced and similar reasons across groups</td>
                <td>Low; All outcomes reported</td>
                <td>High; Response bias (use of self-report)</td>
              </tr>
              <tr valign="top">
                <td>Mendoza et al, 2017 [<xref ref-type="bibr" rid="ref55">55</xref>]</td>
                <td>Low; Missing outcome data balanced and similar reasons across groups</td>
                <td>Low; All outcomes reported</td>
                <td>Low; Appears free of other sources of bias</td>
              </tr>
              <tr valign="top">
                <td>Newton et al, 2009 [<xref ref-type="bibr" rid="ref56">56</xref>]</td>
                <td>Low; Missing outcome data balanced and similar reasons across groups</td>
                <td>Low; All outcomes reported</td>
                <td>High; Response bias (use of self-report)</td>
              </tr>
              <tr valign="top">
                <td>Patrick et al, 2013 [<xref ref-type="bibr" rid="ref57">57</xref>]</td>
                <td>Unclear; Insufficient reporting of reasons for exclusions and dropouts</td>
                <td>Low; All outcomes reported</td>
                <td>High; Response bias (use of self-report)</td>
              </tr>
              <tr valign="top">
                <td>Sirriyeh et al, 2010 [<xref ref-type="bibr" rid="ref58">58</xref>]</td>
                <td>Unclear; Insufficient reporting of reasons for exclusions and dropouts</td>
                <td>High; Missing mean and SD of MET<sup>a</sup> min at time point 1</td>
                <td>High; Response bias (use of self-report), analytical bias (removal of outliers)</td>
              </tr>
              <tr valign="top">
                <td>Straker et al, 2014 [<xref ref-type="bibr" rid="ref59">59</xref>]</td>
                <td>Low; Missing outcome data balanced and similar reasons across groups</td>
                <td>Low; All outcomes reported</td>
                <td>Low; Appears free of other sources of bias</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table5fn1">
              <p><sup>a</sup>MET: metabolic equivalent.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        
        
        <p>For the intervention group, one study found an increase in PA levels between baseline and 3 months and between baseline and 6 months. PA levels decreased in the control condition [<xref ref-type="bibr" rid="ref49">49</xref>]. Assessments of accelerometer counts, light PA, and daily step count showed decreases between baseline and follow-up [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref59">59</xref>].</p>
      </sec>
      <sec>
        <title>Sedentary Behavior</title>
        <p>Studies assessed screen time [<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref54">54</xref>], total SB [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref59">59</xref>], and whether participants performed less than 360 min of PA per week [<xref ref-type="bibr" rid="ref60">60</xref>]. Three interventions found a decrease in screen time between baseline and longest follow-up [<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref52">52</xref>]. One study found an increase in subjectively measured screen time on weekdays, however, a decrease on weekends [<xref ref-type="bibr" rid="ref54">54</xref>]. In one intervention [<xref ref-type="bibr" rid="ref51">51</xref>], subjective SB decreased in the intervention group and increased in the control group between baseline and 12 months. However, objectively measured SB increased for both groups. In 2 studies [<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref57">57</xref>], the intervention groups reduced their total SB between baseline and follow-up, whereas the usual care or control group showed an increase in SB. Another intervention found an increase in SB between baseline and 8 weeks, 3 months, 6 months, and 12 months [<xref ref-type="bibr" rid="ref59">59</xref>]. One intervention resulted in an increase in insufficient PA in the intervention group between baseline and 9 months, although, both the control groups reduced their level of insufficient PA during the same period [<xref ref-type="bibr" rid="ref60">60</xref>]. In another study, SB was the lowest when receiving SMS from a parent but was the highest when receiving them from a behavioral health specialist, followed by SMS from a peer [<xref ref-type="bibr" rid="ref48">48</xref>].</p>
        
        <table-wrap position="float" id="table6">
          <label>Table 6</label>
          <caption>
            <p>Overview of physical activity (PA) and sedentary behavior (SB) outcomes and outcome measures in intervention groups at longest follow-up.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="220"/>
            <col width="220"/>
            <col width="110"/>
            <col width="310"/>
            <col width="110"/>
            <thead>
              <tr valign="top">
                <td colspan="2">Outcome category</td>
                <td>Accelerometer</td>
                <td>Pedometer</td>
                <td>Questionnaire</td>
                <td>Interview</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="2"><bold>Physical activity outcomes</bold></td>
                <td><break/></td>
                <td><break/></td>
                <td><break/></td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Accelerometer counts/min</td>
                <td>Decrease [<xref ref-type="bibr" rid="ref50">50</xref>]</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Light PA min/day</td>
                <td>Decrease [<xref ref-type="bibr" rid="ref59">59</xref>]</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>MVPA<sup>a</sup> %</td>
                <td>Decrease [<xref ref-type="bibr" rid="ref50">50</xref>]</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>MVPA min/week</td>
                <td><break/></td>
                <td>—</td>
                <td>Increase [<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref56">56</xref>]</td>
                <td>Decrease [<xref ref-type="bibr" rid="ref57">57</xref>]</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>MVPA min/day</td>
                <td>Increase [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref55">55</xref>]; decrease [<xref ref-type="bibr" rid="ref54">54</xref>]</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>MPA<sup>b</sup> %</td>
                <td>Decrease [<xref ref-type="bibr" rid="ref51">51</xref>]</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>MPA min/day</td>
                <td>Increase [<xref ref-type="bibr" rid="ref59">59</xref>]</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>VPA<sup>c</sup> %</td>
                <td>Decrease [<xref ref-type="bibr" rid="ref51">51</xref>]</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>VPA min/day</td>
                <td>Increase [<xref ref-type="bibr" rid="ref59">59</xref>]</td>
                <td>—</td>
                <td>—</td>
                <td>—</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>MVPA score</td>
                <td>—</td>
                <td>—</td>
                <td>Increase<sup>d</sup> [<xref ref-type="bibr" rid="ref53">53</xref>]</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>4-day step count</td>
                <td>—</td>
                <td>Decrease [<xref ref-type="bibr" rid="ref56">56</xref>]</td>
                <td><break/></td>
                <td>—</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>MVPA MET<sup>e</sup> min/week</td>
                <td>—</td>
                <td>—</td>
                <td>Increase [<xref ref-type="bibr" rid="ref58">58</xref>]</td>
                <td>—</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>PA days/week</td>
                <td>—</td>
                <td>—</td>
                <td>Increase<sup>f</sup> [<xref ref-type="bibr" rid="ref49">49</xref>]</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td colspan="2"><bold>Sedentary behavior outcomes</bold></td>
                <td><break/></td>
                <td><break/></td>
                <td><break/></td>
                <td><break/></td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Screen time min/day</td>
                <td>—</td>
                <td>—</td>
                <td>Decrease [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref52">52</xref>]; increase and decrease [<xref ref-type="bibr" rid="ref54">54</xref>]</td>
                <td>—</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>Television/computer hours/day</td>
                <td>—</td>
                <td>—</td>
                <td>Decrease<sup>f</sup> [<xref ref-type="bibr" rid="ref49">49</xref>]</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Total SB</td>
                <td>Increase [<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref59">59</xref>]; increase and decrease [<xref ref-type="bibr" rid="ref48">48</xref>]; decrease [<xref ref-type="bibr" rid="ref55">55</xref>]</td>
                <td>—</td>
                <td>Decrease<sup>d</sup> [<xref ref-type="bibr" rid="ref51">51</xref>]; decrease [<xref ref-type="bibr" rid="ref57">57</xref>]</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>PA less than 360 min/week</td>
                <td>—</td>
                <td>—</td>
                <td>Increase [<xref ref-type="bibr" rid="ref60">60</xref>]</td>
                <td>—</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table6fn1">
              <p><sup>a</sup>MVPA: moderate to vigorous physical activity.</p>
            </fn>
            <fn id="table6fn2">
              <p><sup>b</sup>MPA: moderate physical activity.</p>
            </fn>
            <fn id="table6fn3">
              <p><sup>c</sup>VPA: vigorous physical activity.</p>
            </fn>
            <fn id="table6fn4">
              <p><sup>d</sup>Statistically significant (<italic>P</italic>&#60;.05) between baseline and longest follow-up.</p>
            </fn>
            <fn id="table6fn5">
              <p><sup>e</sup>MET: metabolic equivalent.</p>
            </fn>
            <fn id="table6fn6">
              <p><sup>f</sup>Statistically significant (<italic>P</italic>≤.01) between baseline and longest follow-up.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        
        <table-wrap position="float" id="table7">
          <label>Table 7</label>
          <caption>
            <p>Theoretical framework and intervention effectiveness for intervention group at longest follow-up for individual studies.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="270"/>
            <col width="120"/>
            <col width="0"/>
            <col width="120"/>
            <col width="0"/>
            <col width="120"/>
            <col width="0"/>
            <col width="120"/>
            <col width="120"/>
            <col width="0"/>
            <col width="100"/>
            <thead>
              <tr valign="bottom">
                <td colspan="2">Outcome category</td>
                <td>TTM<sup>a</sup></td>
                <td colspan="2">TPB<sup>b</sup></td>
                <td colspan="2">SCT<sup>c</sup></td>
                <td colspan="2">SDT<sup>d</sup></td>
                <td>CCT<sup>e</sup></td>
                <td colspan="2">N/A<sup>f</sup></td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="2"><bold>Physical activity</bold></td>
                <td><break/></td>
                <td colspan="2"><break/></td>
                <td colspan="2"><break/></td>
                <td colspan="2"><break/></td>
                <td><break/></td>
                <td colspan="2"><break/></td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>Brannon et al, 2017 [<xref ref-type="bibr" rid="ref48">48</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td colspan="2">P<sup>g</sup></td>
                <td>—</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>Chen et al, 2017 [<xref ref-type="bibr" rid="ref49">49</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">P<sup>h</sup></td>
                <td>—</td>
                <td colspan="2">—</td>
                <td>—</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>Dewar et al, 2013 [<xref ref-type="bibr" rid="ref50">50</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">N<sup>i</sup></td>
                <td>—</td>
                <td colspan="2">—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Dewar et al, 2014 [<xref ref-type="bibr" rid="ref51">51</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">N</td>
                <td>—</td>
                <td colspan="2">—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Ermetici et al, 2016 [<xref ref-type="bibr" rid="ref52">52</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td colspan="2">—</td>
                <td>P</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>Lau et al, 2012 [<xref ref-type="bibr" rid="ref53">53</xref>]</td>
                <td colspan="2">P<sup>h</sup></td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td colspan="2">—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Lubans et al, 2012 [<xref ref-type="bibr" rid="ref54">54</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">N</td>
                <td>—</td>
                <td colspan="2">—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Mendoza et al, 2017 [<xref ref-type="bibr" rid="ref55">55</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td>P</td>
                <td colspan="2">—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Newton et al, 2009 [<xref ref-type="bibr" rid="ref56">56</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td colspan="2">—</td>
                <td>N</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Patrick et al, 2013 [<xref ref-type="bibr" rid="ref57">57</xref>]</td>
                <td colspan="2">N</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td colspan="2">—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Sirriyeh et al, 2010 [<xref ref-type="bibr" rid="ref58">58</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">P</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td colspan="2">—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Straker et al, 2014 [<xref ref-type="bibr" rid="ref59">59</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td>P</td>
                <td colspan="2">—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td colspan="2"><bold>Sedentary behavior</bold></td>
                <td>—</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td colspan="2">—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Brannon et al, 2017 [<xref ref-type="bibr" rid="ref48">48</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td colspan="2">N, P</td>
                <td>—</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>Chen et al, 2017 [<xref ref-type="bibr" rid="ref49">49</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">P<sup>h</sup></td>
                <td>—</td>
                <td colspan="2">—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Dewar et al, 2013 [<xref ref-type="bibr" rid="ref50">50</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">P</td>
                <td>—</td>
                <td colspan="2">—</td>
                <td>—</td>
              </tr>
              <tr valign="bottom">
                <td><break/></td>
                <td>Dewar et al, 2014 [<xref ref-type="bibr" rid="ref51">51</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">N<sup>j</sup>, P<sup>j</sup></td>
                <td>—</td>
                <td colspan="2">—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Ermetici et al, 2016 [<xref ref-type="bibr" rid="ref52">52</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td colspan="2">—</td>
                <td>P</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Lana et al, 2014 [<xref ref-type="bibr" rid="ref60">60</xref>]</td>
                <td colspan="2">N</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td colspan="2">—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Lubans et al, 2012 [<xref ref-type="bibr" rid="ref54">54</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">P</td>
                <td>—</td>
                <td colspan="2">—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Mendoza et al, 2017 [<xref ref-type="bibr" rid="ref55">55</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td>P</td>
                <td colspan="2">—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Patrick et al, 2013 [<xref ref-type="bibr" rid="ref57">57</xref>]</td>
                <td colspan="2">P</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td>—</td>
                <td colspan="2">—</td>
                <td>—</td>
              </tr>
              <tr valign="top">
                <td><break/></td>
                <td>Straker et al, 2014 [<xref ref-type="bibr" rid="ref59">59</xref>]</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td colspan="2">—</td>
                <td>N</td>
                <td colspan="2">—</td>
                <td>—</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table7fn1">
              <p><sup>a</sup>TTM: transtheoretical model.</p>
            </fn>
            <fn id="table7fn2">
              <p><sup>b</sup>TPB: theory of planned behavior.</p>
            </fn>
            <fn id="table7fn3">
              <p><sup>c</sup>SCT: social cognitive theory.</p>
            </fn>
            <fn id="table7fn4">
              <p><sup>d</sup>SDT: self-determination theory.</p>
            </fn>
            <fn id="table7fn5">
              <p><sup>e</sup>CCT: cybernetic control theory.</p>
            </fn>
            <fn id="table7fn6">
              <p><sup>f</sup>N/A: no theory framework.</p>
            </fn>
            <fn id="table7fn7">
              <p><sup>g</sup>P: positive effect (PA increase, SB decrease).</p>
            </fn>
            <fn id="table7fn8">
              <p><sup>h</sup>Statistically significant (<italic>P</italic>≤.01) between baseline and longest follow-up.</p>
            </fn>
            <fn id="table7fn9">
              <p><sup>i</sup>N: negative effect (PA decrease, SB increase).</p>
            </fn>
            <fn id="table7fn10">
              <p><sup>j</sup>Statistically significant (<italic>P</italic>&#60;.05) between baseline and longest follow-up.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Summary of Evidence</title>
        <p>This review found promising evidence regarding the effectiveness of interventions using SMS to improve PA and SBs. Out of 5 studies assessing MVPA via self-report, 4 found an increase in PA [<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref58">58</xref>] whereas for objectively assessed MVPA, 2 interventions showed an increase [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref55">55</xref>] and one a decrease [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref54">54</xref>]. Four studies resulted in a decrease for objectively assessed accelerometer counts, light PA, MPA, VPA, and step count [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref56">56</xref>,<xref ref-type="bibr" rid="ref59">59</xref>]. One intervention showed an increase in objectively measured MPA and VPA [<xref ref-type="bibr" rid="ref59">59</xref>]. Five studies assessing screen time and total SB using questionnaires demonstrated improvements [<xref ref-type="bibr" rid="ref49">49</xref>-<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref57">57</xref>], whereas objectively measured total SB increased in 3 [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref59">59</xref>] and decreased in 2 studies [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref55">55</xref>]. Of 10 interventions involving PA assessment, 8 resulted in an improvement of at least one PA outcome and of 8 assessing SB outcomes, 5 showed improvements.</p>
        <p>Most interventions included in this review focused on increasing PA, whereas elements targeting SB were scarce. Evidence suggests that distinct assessment and approaches are required to improve PA and SB [<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref62">62</xref>]. Previous meta-analyses have shown greater SB improvements in interventions solely targeting SB compared with PA interventions or those combining PA and SB [<xref ref-type="bibr" rid="ref63">63</xref>,<xref ref-type="bibr" rid="ref64">64</xref>]. To maximize intervention effectiveness, future studies should consider using distinct approaches to improve SB and PA.</p>
        <p>The evidence presented in this review noted a variety of different outcome measures, which led to conflicting findings. For both PA and SB, more studies showed improvements when using subjective measures compared with objective measures. This is in line with previous findings showing subjective measures demonstrate greater enhancements than objective measures [<xref ref-type="bibr" rid="ref65">65</xref>]. As self-report measures demonstrate low to moderate validity for the assessment of PA in children and adolescents, it appears that to assess effectiveness, objective measures such as accelerometers are preferred for both PA and SB [<xref ref-type="bibr" rid="ref66">66</xref>]. For the assessment of the nature and mode of activity being undertaken, subjective measures should be used [<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref66">66</xref>]. Further, a variety of protocols for the assessment and evaluation of participant data has been used. It has been shown that the choice of data reduction protocol when analyzing accelerometer data has a significant effect on the classification of SB and PA time in children [<xref ref-type="bibr" rid="ref67">67</xref>]. There is a continued need for the standardization of methods when using objective measures to assess PA and SB [<xref ref-type="bibr" rid="ref61">61</xref>], and future studies should consider following current recommendations on the assessment of both PA and SB to enhance the comparability of findings between studies and allow more distinct and unbiased conclusions to be drawn.</p>
        <p>Identified studies also used a variety of theoretical frameworks with the more frequent use of the TTM and SCT, consistent with the findings of others [<xref ref-type="bibr" rid="ref29">29</xref>]. Interventions informed by SDT, TPB, or CCT showed improvements in PA, whereas interventions informed by the TTM, SCT, and CCT revealed mixed results for PA and SB. Interventions employing SCT showed more positive results for SB than for PA. Nonetheless, the lack of information provided on how theory was applied within the intervention precludes our ability to confirm these assumptions with certainty. These findings are in line with those of a recent meta-analysis [<xref ref-type="bibr" rid="ref44">44</xref>] that stated it was unclear how specific theoretical frameworks are applied or how they are linked to intervention effectiveness. Thus, our findings do not allow for a judgment on whether the ineffectiveness of some interventions included in this review is due to a lack of appropriate theory derivation and application. Furthermore, conclusions with regard to how theory relates to intervention effectiveness need to be drawn with caution, and more evidence is needed to warrant the use of specific theories when targeting PA and SB in SMS text messaging–based interventions for youth.</p>
        <p>Evidence has shown the increased effectiveness of PA and SB interventions that include the BCTs of goal-setting, self-monitoring, and feedback [<xref ref-type="bibr" rid="ref68">68</xref>]. In this review, 7 studies included goal-setting and monitoring, with 5 showing an increase in PA [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref59">59</xref>]. Two studies additionally included feedback and achieved improvements in PA [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref53">53</xref>]. Four studies that included self-monitoring and goal-setting found an improvement in SB [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref57">57</xref>]. These results are promising and indicate increased intervention effectiveness when including these BCTs in SMS-based interventions targeting PA and SB.</p>
        <p>Previous reviews have shown weaknesses in the design of mHealth interventions [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref36">36</xref>,<xref ref-type="bibr" rid="ref44">44</xref>]. Our findings were in agreement with those reviews and suggest that SMS-based interventions involving adolescents are weak in design and at a high risk of bias. The reasons for high risk of bias were attributed to the use of self-report measures (response bias), a lack of appropriate randomization method (selection bias), and a lack of blinding (detection bias).</p>
        <p>We were also unable to infer the independent effect of SMS due to the lack of appropriate control groups. Only 4 studies employed designs that allowed for the effect of SMS text messaging alone to be assessed [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref60">60</xref>]. Two studies showed a positive effect of SMS on PA [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref58">58</xref>] and 2 on SB [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref57">57</xref>]. However, most studies included a variety of additional intervention components alongside SMS in the intervention and control groups. Definite conclusions with regard to the effectiveness of individual intervention designs, settings, or contents can therefore not be drawn from this review. Future research should employ study designs that allow the examination of the independent effect of SMS on PA and SB to strengthen the evidence base regarding the effectiveness of using SMS alone. Additionally, there is a need for studies exploring which specific SMS text messaging components such as content or frequency of delivery are most effective.</p>
        <p>There is also a continued demand for studies to explore long-term intervention effects on PA and SB [<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref43">43</xref>]. Only 4 interventions lasted for 12 months or longer [<xref ref-type="bibr" rid="ref50">50</xref>-<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref57">57</xref>,<xref ref-type="bibr" rid="ref59">59</xref>]. Two studies assessed PA and SB after 24 months [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref52">52</xref>], with only one showing improvements in PA [<xref ref-type="bibr" rid="ref52">52</xref>] but both showing decreases in SB [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref52">52</xref>]. It has been shown that SMS may be an effective tool to enhance participants’ interest in the long term as well as to improve adherence [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref36">36</xref>]. Therefore, more studies should explore the effectiveness of interventions in achieving sustained behavior change.</p>
        <p>This review shows a high heterogeneity of study designs, intervention components, outcomes, and outcome measures. Possible conclusions regarding effective intervention designs and contents are limited and should be drawn with caution. This review provides some currently limited evidence that the following approaches may result in increased effectiveness of SMS-based interventions for PA and SB in youth:</p>
        <list list-type="order">
          <list-item>
            <p>Specific focus on the desired behavior</p>
          </list-item>
          <list-item>
            <p>Include self-monitoring, goal setting, and feedback components</p>
          </list-item>
          <list-item>
            <p>Send 3 or more SMS per week for PA.</p>
          </list-item>
        </list>
        <p>Furthermore, future research should incorporate the following methodological elements:</p>
        <list list-type="order">
          <list-item>
            <p>Use of objective outcome measures</p>
          </list-item>
          <list-item>
            <p>Include long-term follow-up</p>
          </list-item>
          <list-item>
            <p>Designs that allow assessing the independent effect of SMS.</p>
          </list-item>
        </list>
      </sec>
      <sec>
        <title>Limitations</title>
        <p>The authors were unable to conduct a quantitative data analysis due to high heterogeneity of included studies and a small pool of suitable data consisting of highly heterogeneous interventions and outcome measures. This review included all studies incorporating SMS text messaging as part of their intervention, which resulted in a variety of intervention designs and contents. Consequently, we were unable to draw conclusions with regard to specific intervention elements positively influencing PA and SB. To the best of our knowledge, this review provides the first account of interventions using SMS targeting PA and SB in adolescents. It provides researchers and practitioners with a database of potentially effective components crucial to the development of successful behavior change interventions.</p>
        <p>Existing reviews have employed methods to identify and code theory-based elements such as behavior change techniques of included studies [<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref65">65</xref>]. This review has refrained from following this process for studies not specifying theory base. However, the authors of those studies were contacted and a lack of theoretical foundation was confirmed. Despite the possibility that these interventions were unintentionally and unknowingly based on theory, there was no overt application of theory to study design. Therefore, it is judged to have limited contribution to intervention effectiveness.</p>
        <p>This review does provide a detailed account of the use of theory in SMS-based interventions involving adolescents that, to the best of our knowledge, is novel and crucial for understanding current trends in intervention design and content. Moreover, a rigorous methodology was used for acquiring suitable studies, as well as during the data extraction process. This included hand-searching bibliographies, contacting authors of eligible studies, following recognized guidelines during data extraction, and pilot-testing data extraction items. Existing reviews on technology-based interventions targeting health behavior change have failed to include one or more of these components [<xref ref-type="bibr" rid="ref24">24</xref>-<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref44">44</xref>].</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>This review shows a high level of heterogeneity within SMS-based interventions targeting adolescent PA and SB. The evidence base consists of studies using different objective and self-report outcome measures that employ a variety of protocols, which impairs the ability to synthesize study content and results. Additionally, assessment of the risk of bias showed some limitations in the study and intervention design. Results of the individual as well as across studies should therefore be analyzed with caution. Future research should employ more rigorous research designs, more structured and coherent intervention components, as well as more appropriate and valid outcome measures. Overall, the findings of this study indicate that multicomponent interventions incorporating SMS can be effective in improving PA and SB in adolescents; however, more evidence is needed to further warrant SMS interventions to improve PA and SB.</p>
      </sec>
    </sec>
  </body>
  <back>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">BCT</term>
          <def>
            <p>behavior change technique</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">CCT</term>
          <def>
            <p>cybernetic control theory</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">MET</term>
          <def>
            <p>metabolic equivalent</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">mHealth</term>
          <def>
            <p>mobile health</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">MPA</term>
          <def>
            <p>moderate physical activity</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb6">MVPA</term>
          <def>
            <p>moderate to vigorous physical activity</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb7">PA</term>
          <def>
            <p>physical activity</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb8">SB</term>
          <def>
            <p>sedentary behavior</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb9">SCT</term>
          <def>
            <p>social cognitive theory</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb10">SDT</term>
          <def>
            <p>self-determination theory</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb11">SMS</term>
          <def>
            <p>short message service</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb12">SOC</term>
          <def>
            <p>stage of motivational readiness for change</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb13">TPB</term>
          <def>
            <p>theory of planned behavior</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb14">TTM</term>
          <def>
            <p>transtheoretical model</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb15">VPA</term>
          <def>
            <p>vigorous physical activity</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>This study was funded by the University of the West of Scotland, VP Research Fund. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.</p>
    </ack>
    <fn-group>
      <fn fn-type="con">
        <p>KL performed all literature searches and all aspects of qualitative analysis. RA and DSB contributed to the design and focus of this review. HF and DSB reviewed citations obtained through the electronic literature search and provided judgment of risk of bias for eligible studies. NS reviewed available data for potential inclusion in quantitative analysis. All authors read and approved the final manuscript.</p>
      </fn>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
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