<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "journalpublishing.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="2.0" xml:lang="en" article-type="letter"><front><journal-meta><journal-id journal-id-type="nlm-ta">JMIR Mhealth Uhealth</journal-id><journal-id journal-id-type="publisher-id">mhealth</journal-id><journal-id journal-id-type="index">13</journal-id><journal-title>JMIR mHealth and uHealth</journal-title><abbrev-journal-title>JMIR Mhealth Uhealth</abbrev-journal-title><issn pub-type="epub">2291-5222</issn><publisher><publisher-name>JMIR Publications</publisher-name><publisher-loc>Toronto, Canada</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">v12i1e65277</article-id><article-id pub-id-type="doi">10.2196/65277</article-id><article-categories><subj-group subj-group-type="heading"><subject>Letter to the Editor</subject></subj-group></article-categories><title-group><article-title>Evaluating the Sensitivity of Wearable Devices in Posttranscatheter Aortic Valve Implantation Functional Assessment</article-title></title-group><contrib-group><contrib contrib-type="author" equal-contrib="yes"><name name-style="western"><surname>An</surname><given-names>Jinghui</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff1"/><xref ref-type="fn" rid="equal-contrib1">*</xref></contrib><contrib contrib-type="author" equal-contrib="yes"><name name-style="western"><surname>Shi</surname><given-names>Fengwu</given-names></name><degrees>MM</degrees><xref ref-type="aff" rid="aff1"/><xref ref-type="fn" rid="equal-contrib1">*</xref></contrib><contrib contrib-type="author" equal-contrib="yes"><name name-style="western"><surname>Wang</surname><given-names>Huajun</given-names></name><degrees>MM</degrees><xref ref-type="aff" rid="aff1"/><xref ref-type="fn" rid="equal-contrib1">*</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Zhang</surname><given-names>Hang</given-names></name><degrees>MM</degrees><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author" corresp="yes"><name name-style="western"><surname>Liu</surname><given-names>Su</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff id="aff1"><institution>Department of Cardiac Surgery, the Second Hospital of Hebei Medical University</institution>, <addr-line>No 215, Heping West Road</addr-line><addr-line>Shijiazhuang</addr-line>, <country>China</country></aff><contrib-group><contrib contrib-type="editor"><name name-style="western"><surname>Prairie</surname><given-names>Kathy</given-names></name></contrib><contrib contrib-type="editor"><name name-style="western"><surname>Cardoso</surname><given-names>Taiane de Azevedo</given-names></name></contrib></contrib-group><author-notes><corresp>Correspondence to Su Liu, MD, Department of Cardiac Surgery, the Second Hospital of Hebei Medical University, No. 215, Heping West Road, Shijiazhuang, 050000, China, 86 0311-66002999; <email>anjinghui2010@163.com</email></corresp><fn fn-type="equal" id="equal-contrib1"><label>*</label><p>these authors contributed equally</p></fn></author-notes><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>8</day><month>11</month><year>2024</year></pub-date><volume>12</volume><elocation-id>e65277</elocation-id><history><date date-type="received"><day>11</day><month>08</month><year>2024</year></date><date date-type="accepted"><day>20</day><month>08</month><year>2024</year></date></history><copyright-statement>&#x00A9; Jinghui An, Fengwu Shi, Huajun Wang, Hang Zhang, Su Liu. Originally published in JMIR mHealth and uHealth (<ext-link ext-link-type="uri" xlink:href="https://mhealth.jmir.org">https://mhealth.jmir.org</ext-link>), 8.11.2024. </copyright-statement><copyright-year>2024</copyright-year><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR mHealth and uHealth, is properly cited. The complete bibliographic information, a link to the original publication on <ext-link ext-link-type="uri" xlink:href="https://mhealth.jmir.org/">https://mhealth.jmir.org/</ext-link>, as well as this copyright and license information must be included.</p></license><self-uri xlink:type="simple" xlink:href="https://mhealth.jmir.org/2024/1/e65277"/><related-article related-article-type="commentary article" ext-link-type="doi" xlink:href="10.2196/53964" xlink:title="Comment on" xlink:type="simple">https://mhealth.jmir.org/2024/1/e53964</related-article><kwd-group><kwd>aortic valve</kwd><kwd>implantation functional</kwd><kwd>wearable devices</kwd></kwd-group></article-meta></front><body><p>I read with great interest the recent article by Eerdekens et al [<xref ref-type="bibr" rid="ref1">1</xref>] titled &#x201C;Cardiac Health Assessment Using a Wearable Device Before and After Transcatheter Aortic Valve Implantation: Prospective Study,&#x201D; published in <italic>JMIR mHealth and uHealth</italic>. The study presented an innovative approach by using a wearable device to assess cardiac health outcomes before and after transcatheter aortic valve implantation (TAVI), addressing an important gap in the objective evaluation of functional improvement post TAVI.</p><p>While the findings of the study were significant, particularly the introduction of the Cardiac Energy Expenditure Slope (CEES) as a potential metric for assessing cardiovascular efficiency, there were some critical considerations that merited discussion.</p><p>First, the study&#x2019;s conclusion that wearable device parameters, such as step count and total activity time, did not significantly change post TAVI, raised questions about the sensitivity of these devices in capturing subtle improvements in daily activity. It is well established that older populations, especially those undergoing TAVI, may not exhibit dramatic changes in physical activity due to a combination of frailty, preexisting comorbidities, and lifestyle factors [<xref ref-type="bibr" rid="ref2">2</xref>-<xref ref-type="bibr" rid="ref5">5</xref>]. However, the lack of significant change in these parameters might also reflect limitations in the wearable device&#x2019;s ability to capture variations in physical activity that are clinically meaningful but subtle. For instance, improvements in quality of life and functional capacity may have manifested in ways that were not fully captured by metrics like step count alone.</p><p>Second, the study&#x2019;s reliance on a 3-month follow-up period to assess post-TAVI outcomes could be seen as a limitation. While the authors argued that most patients reach full capacity by this time, it is possible that some patients might show delayed improvements in physical activity and cardiovascular efficiency. Extending the follow-up period to 6 months or even a year could have provided a more comprehensive view of the long-term impact of TAVI on patient activity levels and cardiac health.</p><p>Additionally, the introduction of CEES as a novel metric was intriguing, yet its application and utility needed further validation in larger, diverse cohorts. The metric&#x2019;s correlation with traditional measures of functional improvement, such as the 6-minute walking test, and its predictive value in long-term outcomes post TAVI, should be explored in future studies. This would help establish CEES as a reliable tool in both clinical practice and research settings.</p><p>In conclusion, while the study by Eerdekens et al [<xref ref-type="bibr" rid="ref1">1</xref>] contributed valuable insights into the use of wearable devices for cardiac health assessment, it also highlighted the need for further research to optimize these tools for older, comorbid populations. Continued exploration into novel metrics like CEES and longer follow-up periods could enhance our understanding of post-TAVI recovery and guide personalized treatment strategies.</p></body><back><fn-group><fn fn-type="conflict"><p>None declared.</p></fn><fn fn-type="other"><p><bold>Editorial Notice</bold></p><p>The corresponding author of &#x201C;Cardiac Health Assessment Using a Wearable Device Before and After Transcatheter Aortic Valve Implantation: Prospective Study&#x201D; declined to respond to this letter.</p></fn></fn-group><glossary><title>Abbreviations</title><def-list><def-item><term id="abb1">CEES</term><def><p>Cardiac Energy Expenditure Slope</p></def></def-item><def-item><term id="abb2">TAVI</term><def><p>transcatheter aortic valve implantation</p></def></def-item></def-list></glossary><ref-list><title>References</title><ref id="ref1"><label>1</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Eerdekens</surname><given-names>R</given-names> </name><name name-style="western"><surname>Zelis</surname><given-names>J</given-names> </name><name name-style="western"><surname>Ter Horst</surname><given-names>H</given-names> </name><etal/></person-group><article-title>Cardiac health assessment using a wearable device before and after transcatheter aortic valve implantation: prospective study</article-title><source>JMIR mHealth uHealth</source><year>2024</year><month>06</month><day>3</day><volume>12</volume><fpage>e53964</fpage><pub-id pub-id-type="doi">10.2196/53964</pub-id><pub-id pub-id-type="medline">38832585</pub-id></nlm-citation></ref><ref id="ref2"><label>2</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Tsevat</surname><given-names>J</given-names> </name><name name-style="western"><surname>Dawson</surname><given-names>NV</given-names> </name></person-group><article-title>Health values of hospitalized patients 80 years or older</article-title><source>JAMA</source><year>1998</year><month>02</month><day>4</day><volume>279</volume><issue>5</issue><fpage>371</fpage><pub-id pub-id-type="doi">10.1001/jama.279.5.371</pub-id></nlm-citation></ref><ref id="ref3"><label>3</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Kim</surname><given-names>CA</given-names> </name><name name-style="western"><surname>Rasania</surname><given-names>SP</given-names> </name><name name-style="western"><surname>Afilalo</surname><given-names>J</given-names> </name><name name-style="western"><surname>Popma</surname><given-names>JJ</given-names> </name><name name-style="western"><surname>Lipsitz</surname><given-names>LA</given-names> </name><name name-style="western"><surname>Kim</surname><given-names>DH</given-names> </name></person-group><article-title>Functional status and quality of life after transcatheter aortic valve replacement: a systematic review</article-title><source>Ann Intern Med</source><year>2014</year><month>02</month><day>18</day><volume>160</volume><issue>4</issue><fpage>243</fpage><lpage>254</lpage><pub-id pub-id-type="doi">10.7326/M13-1316</pub-id><pub-id pub-id-type="medline">24727842</pub-id></nlm-citation></ref><ref id="ref4"><label>4</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Afilalo</surname><given-names>J</given-names> </name><name name-style="western"><surname>Lauck</surname><given-names>S</given-names> </name><name name-style="western"><surname>Kim</surname><given-names>DH</given-names> </name><etal/></person-group><article-title>Frailty in older adults undergoing aortic valve replacement</article-title><source>J Am Coll Cardiol</source><year>2017</year><month>08</month><volume>70</volume><issue>6</issue><fpage>689</fpage><lpage>700</lpage><pub-id pub-id-type="doi">10.1016/j.jacc.2017.06.024</pub-id><pub-id pub-id-type="medline">28693934</pub-id></nlm-citation></ref><ref id="ref5"><label>5</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Green</surname><given-names>P</given-names> </name><name name-style="western"><surname>Arnold</surname><given-names>SV</given-names> </name><name name-style="western"><surname>Cohen</surname><given-names>DJ</given-names> </name><etal/></person-group><article-title>Relation of frailty to outcomes after transcatheter aortic valve replacement (from the PARTNER trial)</article-title><source>Am J Cardiol</source><year>2015</year><month>07</month><day>15</day><volume>116</volume><issue>2</issue><fpage>264</fpage><lpage>269</lpage><pub-id pub-id-type="doi">10.1016/j.amjcard.2015.03.061</pub-id><pub-id pub-id-type="medline">25963221</pub-id></nlm-citation></ref></ref-list></back></article>