<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "journalpublishing.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="2.0" xml:lang="en" article-type="review-article"><front><journal-meta><journal-id journal-id-type="nlm-ta">JMIR Mhealth Uhealth</journal-id><journal-id journal-id-type="publisher-id">mhealth</journal-id><journal-id journal-id-type="index">13</journal-id><journal-title>JMIR mHealth and uHealth</journal-title><abbrev-journal-title>JMIR Mhealth Uhealth</abbrev-journal-title><issn pub-type="epub">2291-5222</issn><publisher><publisher-name>JMIR Publications</publisher-name><publisher-loc>Toronto, Canada</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">v14i1e77341</article-id><article-id pub-id-type="doi">10.2196/77341</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Postoperative Telerehabilitation in Patients With Hip Fracture: Systematic Review and Meta-Analysis</article-title></title-group><contrib-group><contrib contrib-type="author" equal-contrib="yes"><name name-style="western"><surname>Cai</surname><given-names>Can-xin</given-names></name><degrees>MSc</degrees><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref><xref ref-type="fn" rid="equal-contrib1">*</xref></contrib><contrib contrib-type="author" equal-contrib="yes"><name name-style="western"><surname>Qin</surname><given-names>Penny Ping</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff3">3</xref><xref ref-type="fn" rid="equal-contrib1">*</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Liu</surname><given-names>Chuan-yao</given-names></name><degrees>BSc</degrees><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Cai</surname><given-names>Peng</given-names></name><degrees>MSc</degrees><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author" corresp="yes"><name name-style="western"><surname>Wei</surname><given-names>Xijun</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref><xref ref-type="aff" rid="aff4">4</xref></contrib></contrib-group><aff id="aff1"><institution>Rehabilitation Laboratory of Mixed Reality, Shenzhen Hospital, Southern Medical University</institution><addr-line>Shenzhen</addr-line><country>China</country></aff><aff id="aff2"><institution>Department of Rehabilitation Medicine, Shenzhen Hospital, Southern Medical University</institution><addr-line>13 Xinhu Road, Bao'an District</addr-line><addr-line>Shenzhen</addr-line><country>China</country></aff><aff id="aff3"><institution>Department of Rehabilitation Sciences, Faculty of Health and Social Sciences, Hong Kong Polytechnic University</institution><addr-line>Hong Kong Special Administrative Region</addr-line><country>China (Hong Kong)</country></aff><aff id="aff4"><institution>Department of Occupational Therapy, School of Rehabilitation Sciences, Southern Medical University</institution><addr-line>Shenzhen</addr-line><country>China</country></aff><contrib-group><contrib contrib-type="editor"><name name-style="western"><surname>Zhou</surname><given-names>Junhong</given-names></name></contrib></contrib-group><contrib-group><contrib contrib-type="reviewer"><name name-style="western"><surname>Cedeno-Veloz</surname><given-names>Bernardo</given-names></name></contrib><contrib contrib-type="reviewer"><name name-style="western"><surname>Chi Bun</surname><given-names>YIP</given-names></name></contrib><contrib contrib-type="reviewer"><name name-style="western"><surname>Lin</surname><given-names>Pei-Chin</given-names></name></contrib><contrib contrib-type="reviewer"><name name-style="western"><surname>He</surname><given-names>Wan-jia</given-names></name></contrib></contrib-group><author-notes><corresp>Correspondence to Xijun Wei, PhD, Department of Rehabilitation Medicine, Shenzhen Hospital, Southern Medical University, 13 Xinhu Road, Bao'an District, Shenzhen, 518101, China, 86 755-23360806; <email>weixj2016@smu.edu.cn</email></corresp><fn fn-type="equal" id="equal-contrib1"><label>*</label><p>these authors contributed equally</p></fn></author-notes><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>9</day><month>3</month><year>2026</year></pub-date><volume>14</volume><elocation-id>e77341</elocation-id><history><date date-type="received"><day>12</day><month>05</month><year>2025</year></date><date date-type="rev-recd"><day>09</day><month>01</month><year>2026</year></date><date date-type="accepted"><day>19</day><month>01</month><year>2026</year></date></history><copyright-statement>&#x00A9; Can-xin Cai, Penny Ping Qin, Chuan-yao Liu, Peng Cai, Xijun Wei. Originally published in JMIR mHealth and uHealth (<ext-link ext-link-type="uri" xlink:href="https://mhealth.jmir.org">https://mhealth.jmir.org</ext-link>), 9.3.2026. </copyright-statement><copyright-year>2026</copyright-year><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR mHealth and uHealth, is properly cited. The complete bibliographic information, a link to the original publication on <ext-link ext-link-type="uri" xlink:href="https://mhealth.jmir.org/">https://mhealth.jmir.org/</ext-link>, as well as this copyright and license information must be included.</p></license><self-uri xlink:type="simple" xlink:href="https://mhealth.jmir.org/2026/1/e77341"/><abstract><sec><title>Background</title><p>Telerehabilitation programs use information and communications technologies to facilitate exercise training, self-management education, and health behavior modifications for nonhospitalized patients. In recent years, 2 systematic reviews have examined the effectiveness of telerehabilitation in the recovery of patients with hip fractures but have yielded inconsistent results. This is a significant gap because tools to assess clinical domains such as pain, range of motion, and deformity are crucial for patient outcomes. Moreover, the long-term effects of telerehabilitation on postoperative functional recovery in patients with hip fractures have not been investigated.</p></sec><sec><title>Objective</title><p>To address the abovementioned research gap, this systematic review aimed to evaluate the short- and long-term effects of telerehabilitation on postoperative functional recovery in patients with hip fractures.</p></sec><sec sec-type="methods"><title>Methods</title><p>We searched the PubMed, Cochrane Library, Embase, and Web of Science databases from inception to March 31, 2025. Randomized controlled trials investigating the effect of postoperative telerehabilitation in patients with hip fractures were included in this systematic review. Outcomes of interest included hip function measured using the Harris Hip Score; functional mobility measured using the Short Physical Performance Battery and the timed up and go test; and ability to perform basic activities of daily living measured using the Functional Independence Measure, Barthel index, or modified Barthel index. Meta-analyses were performed using the RevMan software (version 5.3).</p></sec><sec sec-type="results"><title>Results</title><p>A thorough literature search conducted in April 2025 yielded a total of 8 studies involving 740 patients for inclusion in this systematic review. Meta-analysis showed that telerehabilitation was effective for improving the Harris Hip Score at the intervention end point (2 included studies involving 156 participants; mean difference [MD] 7.42, 95% CI 5.61-9.23; <italic>P</italic>&#x003C;.001; <italic>I</italic><sup>2</sup>=3%), the Short Physical Performance Battery score at the end point (4 included studies involving 430 participants; MD 1.34, 95% CI 1.14-1.55; <italic>P</italic>&#x003C;.001; <italic>I</italic><sup>2</sup>=33%) and at follow-up (2 included studies involving 292 participants; MD 1.17, 95% CI 1.00-1.34; <italic>P</italic>&#x003C;.001; <italic>I</italic><sup>2</sup>=0%), the timed up and go score at the end point (4 included studies involving 156 participants; MD &#x2013;8.45, 95% CI &#x2212;11.28 to &#x2212;5.62; <italic>P</italic>&#x003C;.001; <italic>I</italic><sup>2</sup>=0%) and at follow-up (2 included studies involving 63 participants; MD &#x2212;7.66, 95% CI &#x2212;13.78 to &#x2212;1.53; <italic>P</italic>=.01; <italic>I</italic><sup>2</sup>=0%), and ability to perform basic activities of daily living at the end point (5 included studies involving 354 participants; standardized MD 1.65, 95% CI 0.78-2.51; <italic>P</italic>&#x003C;.001; <italic>I</italic><sup>2</sup>=91%) and at follow-up (standardized MD 0.43, 95% CI 0.05-0.81; <italic>P</italic>=.03; <italic>I</italic><sup>2</sup>=48%).</p></sec><sec sec-type="conclusions"><title>Conclusions</title><p>Our review found that postoperative telerehabilitation may benefit short- and long-term functional recovery in patients with hip fractures compared to conventional rehabilitation. However, the evidence was weak due to the limited number and insufficient quality of the included studies and the heterogeneity across the studies.</p></sec><sec><title>Trial Registration</title><p>PROSPERO CRD42024498569; https://www.crd.york.ac.uk/PROSPERO/view/CRD42024498569</p></sec></abstract><kwd-group><kwd>hip fracture</kwd><kwd>postoperation</kwd><kwd>telerehabilitation</kwd><kwd>systematic review</kwd><kwd>meta-analysis</kwd></kwd-group></article-meta></front><body><sec id="s1" sec-type="intro"><title>Introduction</title><p>Hip fractures are a major global public health challenge, with an annual incidence of over 10 million cases [<xref ref-type="bibr" rid="ref1">1</xref>]. They are most prevalent among adults aged 65 years and older, a population in which fractures are correlated with high mortality rates and a substantial burden on patients and their families [<xref ref-type="bibr" rid="ref2">2</xref>]. The standard management for hip fractures involves surgical intervention followed by rehabilitation to restore walking ability [<xref ref-type="bibr" rid="ref3">3</xref>,<xref ref-type="bibr" rid="ref4">4</xref>]. Despite this, most older patients fail to recover their prefracture level of function, and this persistent impairment may lead to an increased risk of falls [<xref ref-type="bibr" rid="ref5">5</xref>]. Therefore, long-term postoperative management for older adults with hip fractures is essential to enhance their functional recovery and overall quality of life.</p><p>Since the COVID-19 pandemic, telerehabilitation has gained popularity, with physical therapists increasingly willing to incorporate it into their routine practices, prompting health care facilities to adopt innovative methods for engaging with patients. As a branch of telemedicine, telerehabilitation is defined as the use of remote health care methodologies, specifically information and communications technologies, to deliver therapeutic rehabilitation services outside of medical institutions [<xref ref-type="bibr" rid="ref6">6</xref>]. Telerehabilitation programs use information and communications technologies such as telephones and videoconferencing to facilitate exercise training, self-management, and lifestyle modifications for nonhospitalized patients [<xref ref-type="bibr" rid="ref7">7</xref>,<xref ref-type="bibr" rid="ref8">8</xref>].</p><p>In recent years, several systematic reviews have been published regarding the effectiveness of telerehabilitation programs for patients with specific chronic diseases, including cardiac, respiratory, and neurological disorders [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref10">10</xref>]. Of note, 2 previous systematic reviews have examined the effectiveness of postoperative telerehabilitation in the recovery of patients with hip fractures, yielding inconsistent results. One review found that, compared to conventional intervention, telerehabilitation was not effective in improving postoperative mobility (as measured using the timed up and go [TUG] test and gait speed) or in alleviating pain but facilitated the ability to perform basic activities of daily living (BADLs) with a clinically irrelevant improvement [<xref ref-type="bibr" rid="ref11">11</xref>]. Another recently published systematic review found that, compared to traditional rehabilitation, digital health interventions significantly improved postoperative mobility and the ability to perform BADLs, as indicated by the improvement in the TUG performance, the Short Physical Performance Battery (SPPB) score, and the Functional Independence Measure (FIM) score [<xref ref-type="bibr" rid="ref12">12</xref>]. However, specific measurement tools for hip function, such as the Harris Hip Score (HHS), have not been examined in any systematic review. This is a significant research gap because these tools assess crucial clinical domains, including pain, range of motion, and deformity, that are key outcomes for patients with hip fractures. Moreover, the long-term effects of telerehabilitation on postoperative functional recovery in patients with hip fractures have not been investigated.</p><p>Therefore, this systematic review aimed to evaluate the short- and long-term effects of telerehabilitation on postoperative functional recovery in patients with hip fractures. The outcomes of interest included hip function as measured using the HHS [<xref ref-type="bibr" rid="ref13">13</xref>]; functional mobility as measured using the TUG test [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref15">15</xref>] and SPPB [<xref ref-type="bibr" rid="ref16">16</xref>-<xref ref-type="bibr" rid="ref18">18</xref>]; and ability to perform BADLs as measured using the Barthel index (BI), modified BI (MBI), or FIM. We hypothesized that telerehabilitation would be effective for improving postoperative short- and long-term functional recovery in patients with hip fractures compared to conventional rehabilitation.</p></sec><sec id="s2" sec-type="methods"><title>Methods</title><p>This systematic review and meta-analysis adhered to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020 guidelines [<xref ref-type="bibr" rid="ref19">19</xref>], with a registration in PROSPERO (CRD42024498569).</p><sec id="s2-1"><title>Literature Search</title><p>Two researchers (CC and PPQ) independently searched the PubMed, Embase, Web of Science, and CENTRAL databases from inception to March 31, 2025. The search was limited to English-language literature. Randomized controlled trials investigating the effectiveness of postoperative telerehabilitation treatment for patients with hip fractures were included (<xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>).</p><p>Additional articles were identified by reviewing the reference lists of relevant reviews. The following keywords and the corresponding MeSH (Medical Subject Headings) terms were used: (telerehabilitation OR telerehabilitations OR tele-rehabilitation OR tele-rehabilitations OR remote rehabilitation OR remote rehabilitations OR rehabilitation, remote OR rehabilitations, remote OR virtual rehabilitation OR virtual rehabilitations OR rehabilitation, virtual OR rehabilitations, virtual) AND (hip fractures OR fractures, hip OR intertrochanteric fracture OR intertrochanteric fractures OR trochanteric fractures OR fractures, trochanteric OR femur trochlear fracture OR femur trochlear fractures OR trochlear fracture, femur OR trochlear fractures, femur OR fractures, femur trochlear OR femoral trochlear fracture OR femoral trochlear fractures OR fracture, femoral trochlear OR fractures, femoral trochlear OR trochlear fracture, femoral OR trochlear fractures, femoral OR subtrochanteric fracture OR subtrochanteric fractures).</p></sec><sec id="s2-2"><title>Eligibility Criteria</title><p>The inclusion criteria were as follows: (1) studies involving participants diagnosed with a hip fracture who were in a stable condition (no further fractures were observed or reported) after surgical intervention; (2) studies involving telerehabilitation as the primary intervention following surgery, including the use of SMS text messaging, telephones, smartphones, and internet-based and software-based methods; (3) studies that reported at least one outcome of interest, including the HHS, TUG test, SPPB score, BI, MBI, and FIM; and (4) randomized controlled trials.</p><p>The exclusion criteria were (1) only study protocol or conference abstract available and (2) unavailability of the full text.</p></sec><sec id="s2-3"><title>Study Selection</title><p>The search results were imported into EndNote X9 (Clarivate Analytics) for duplicate removal. To ensure the accuracy of this process, 2 authors (CC and PPQ) manually verified the deleted duplicates. The titles and abstracts of the remaining records were then screened independently by these authors (CC and PPQ). Full texts were retrieved for further review if deemed eligible by either author. Any disagreements between the reviewers were resolved through discussion with a third author (CL).</p></sec><sec id="s2-4"><title>Data Extraction</title><p>Two authors (CC and PPQ) independently extracted data from the included studies. The extracted data encompassed the following: basic study information (the first author, publication year, and country), participant baseline characteristics (sample size, age, and gender), details of the telerehabilitation and control interventions, and outcome measures (including follow-up period and measurement tools).</p></sec><sec id="s2-5"><title>Quality Evaluation</title><p>Two authors (CC and PPQ) independently evaluated the quality of the included studies using version 2 of the Cochrane risk-of-bias tool for randomized trials [<xref ref-type="bibr" rid="ref20">20</xref>]. The risk-of-bias assessment consisted of the following domains: (1) randomization process, (2) deviations from intended interventions, (3) missing outcome data, (4) measurement of the outcome, and (5) selection of the reported results. The overall risk of bias was classified as low risk of bias, some concerns, and high risk of bias.</p></sec><sec id="s2-6"><title>Data Analysis</title><p>The Cochrane Collaboration&#x2019;s Review Manager software (version 5.3) was used for all statistical analyses. The overall estimate of the treatment effect was calculated using the means and SDs of outcome scores for continuous data in the telerehabilitation intervention and control groups. Short- and long-term effects were analyzed by comparing the differences in outcome scores between the 2 groups at the intervention end point and at the last follow-up time point, respectively. For studies using the same measurement tool, we calculated a pooled estimate of the mean differences (MDs) with 95% CIs. In cases in which different measurement tools were used, we used standardized MDs (SMDs).</p><p>To investigate potential clinical and methodological heterogeneity across the included studies, the following factors were summarized and compared: (1) patient characteristics (age and baseline scores of the outcomes of interest), (2) characteristics of telerehabilitation (duration, frequency, and delivery mode), (3) type of control intervention, (4) follow-up period for the outcomes of interest, and (5) risk of bias. Where low clinical and methodological heterogeneity was found across the studies in a given meta-analysis, a fixed-effects model was used; otherwise, a random-effects model was applied. Statistical heterogeneity was quantified using the <italic>I</italic><sup>2</sup> statistic. <italic>I</italic><sup>2</sup> values greater than 50% were considered to indicate substantial heterogeneity [<xref ref-type="bibr" rid="ref21">21</xref>]. When substantial statistical heterogeneity was present and a sufficient number of studies were available, subgroup analyses were performed based on the abovementioned factors contributing to clinical or methodological heterogeneity. Furthermore, a sensitivity analysis was planned to assess the impact on the pooled results provided that a sufficient number of studies were available. This was performed by excluding studies with a high risk of bias or those that differed substantially from others in the factors considered for subgroup analyses.</p></sec></sec><sec id="s3" sec-type="results"><title>Results</title><sec id="s3-1"><title>Study Identification</title><p>The initial database search yielded a total of 1045 records, of which 6 (0.6%) met the eligibility criteria and were included. A further 2 studies were identified by checking the reference lists of relevant reviews [<xref ref-type="bibr" rid="ref11">11</xref>], resulting in a total of 8 studies for the systematic review and meta-analysis. The study selection process is illustrated in the PRISMA flow diagram (<xref ref-type="fig" rid="figure1">Figure 1</xref>).</p><fig position="float" id="figure1"><label>Figure 1.</label><caption><p>Flow diagram for the systematic search. RCT: randomized controlled trial.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="mhealth_v14i1e77341_fig01.png"/></fig></sec><sec id="s3-2"><title>Study Characteristics</title><p>The 8 included studies comprised 740 patients, including 569 female and 161 male individuals. The sample sizes varied from 31 to 232 in the individual studies.</p><p>The treatment strategies for postoperative telerehabilitation for patients with hip fractures included strengthening, balance, coordination, stretching exercises, BADL training, introduction of walking aids, and safety education. Most included studies provided telerehabilitation through mobile apps or software [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref28">28</xref>] supervised by professionals remotely, one study used a DVD supervised via telephone calls [<xref ref-type="bibr" rid="ref27">27</xref>], and one study used a telephone call as the primary strategy [<xref ref-type="bibr" rid="ref28">28</xref>]. The control interventions comprised home-based exercise through written materials [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref26">26</xref>], in-person rehabilitation [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref24">24</xref>], follow-up assessment through telephone [<xref ref-type="bibr" rid="ref22">22</xref>] and health nutrition education [<xref ref-type="bibr" rid="ref27">27</xref>], and no intervention [<xref ref-type="bibr" rid="ref28">28</xref>]. The duration of telerehabilitation varied from 35 minutes to 6 months. The follow-up periods varied from 3 weeks to 9 months [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref25">25</xref>-<xref ref-type="bibr" rid="ref28">28</xref>]. <xref ref-type="table" rid="table1">Table 1</xref> presents the main characteristics of the included studies [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref28">28</xref>].</p><table-wrap id="t1" position="float"><label>Table 1.</label><caption><p>Characteristics of the included studies.</p></caption><table id="table1" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Study and country</td><td align="left" valign="bottom">Participants</td><td align="left" valign="bottom">Telerehabilitation</td><td align="left" valign="bottom">Control intervention</td><td align="left" valign="bottom">Outcome measures</td><td align="left" valign="bottom">Time points of outcome measurement</td></tr></thead><tbody><tr><td align="left" valign="top">Kalron et al [<xref ref-type="bibr" rid="ref26">26</xref>], 2018, Israel</td><td align="left" valign="top">Sample size: 15 in telerehabilitation vs 17 in control group (female: 10/15 vs 9/17, respectively); age: mean 65.7, SD 7.8 y vs mean 67.3, SD 9.5 y</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Home-based training program through software, including exercises for movement, strengthening the lower limbs, and balance; 40-50 min per session, 3 times per week for 6 weeks</p></list-item><list-item><p>Supervised by professionals through the software</p></list-item></list></td><td align="left" valign="top">Home-based exercises through an exercise booklet (exercises were similar to those in the telerehabilitation group)</td><td align="left" valign="top">TUG<sup><xref ref-type="table-fn" rid="table1fn1">a</xref></sup> test</td><td align="left" valign="top">Intervention end point: 6 weeks; follow-up: 4 weeks after the intervention</td></tr><tr><td align="left" valign="top">Li et al [<xref ref-type="bibr" rid="ref25">25</xref>], 2022, China</td><td align="left" valign="top">Sample size: 15 in telerehabilitation vs 16 in control group (female: 14/15 vs 11/16, respectively); age: mean 76.5, SD 8.6 y vs mean 82.1, SD 9.7 y</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Home-based training program through mobile app, including trunk and lower-extremity strengthening and stretching, coordination, balance, and functional exercises related to ADLs<sup><xref ref-type="table-fn" rid="table1fn2">b</xref></sup>, for 3 weeks</p></list-item><list-item><p>Supervised by professionals through the mobile app</p></list-item></list></td><td align="left" valign="top">Home-based training through written sheets (exercises were equivalent to those in the telerehabilitation group)</td><td align="left" valign="top">TUG test and MBI<sup><xref ref-type="table-fn" rid="table1fn3">c</xref></sup></td><td align="left" valign="top">Intervention end point: 3 weeks; follow-up: 3 weeks after the intervention</td></tr><tr><td align="left" valign="top">Ortiz-Pi&#x00F1;a et al [<xref ref-type="bibr" rid="ref24">24</xref>], 2021, Spain</td><td align="left" valign="top">Sample size: 35 in telerehabilitation vs 36 in control group (female: 26/35 vs 27/36, respectively); age: mean 76.71, SD 6.04 y vs mean 80.72, SD 5.59 y</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Home-based training through software, including lower- and upper-body strengthening, balance, cardiovascular exercises, and occupational therapy (ADL training and introduction to walking aids); 50-60 min per session for 12 weeks</p></list-item><list-item><p>Supervised by caregivers</p></list-item></list></td><td align="left" valign="top">Home-based in-person rehabilitation, including 5-15 sessions of physiotherapy and occupational therapy</td><td align="left" valign="top">TUG test, SPPB<sup><xref ref-type="table-fn" rid="table1fn4">d</xref></sup>, and FIM<sup><xref ref-type="table-fn" rid="table1fn5">e</xref></sup></td><td align="left" valign="top">Intervention end point: 12 weeks; follow-up: N/A<sup><xref ref-type="table-fn" rid="table1fn6">f</xref></sup></td></tr><tr><td align="left" valign="top">Wu et al [<xref ref-type="bibr" rid="ref5">5</xref>], 2022, China</td><td align="left" valign="top">Sample size: 43 in telerehabilitation vs 42 in control group (female: 30/43 vs 31/42, respectively); age: mean 74.28, SD 5.06 y vs mean 72.0, SD 6.77 y</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Home-based training through software, including cardiopulmonary function exercise and balance exercises, ADL training, and introduction to walking aids, for 6 months</p></list-item><list-item><p>Supervised by professionals through the software and communication with professionals through videoconferencing</p></list-item></list></td><td align="left" valign="top">Home-based rehabilitation through a written text and communication with professionals through phone calls and outpatient service</td><td align="left" valign="top">HHS<sup><xref ref-type="table-fn" rid="table1fn7">g</xref></sup> and FIM</td><td align="left" valign="top">Intervention end point: 6 months; follow-up: N/A</td></tr><tr><td align="left" valign="top">Zhang et al [<xref ref-type="bibr" rid="ref22">22</xref>], 2022, China</td><td align="left" valign="top">Hip replacement group sample size: 17 in telerehabilitation vs 14 in control group; internal fixation group sample size: 10 in telerehabilitation vs 10 in control group</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Home-based training through a mobile app, including education and walking, balance, and stair-walking exercises, for 3 months</p></list-item><list-item><p>Supervised by professionals through the mobile app</p></list-item></list></td><td align="left" valign="top">Follow-up assessment through telephone</td><td align="left" valign="top">HHS, FIM, TUG test, and SPPB</td><td align="left" valign="top">During the intervention period: at 2 weeks and 2 months; intervention end point: 3 months; follow-up: N/A</td></tr><tr><td align="left" valign="top">Prieto-Moreno et al [<xref ref-type="bibr" rid="ref23">23</xref>], 2024, Portugal</td><td align="left" valign="top">Sample size: 51 in telerehabilitation vs 54 in control group (female: 37/51 vs 38/54, respectively); age: mean 79.55, SD 7.11 y vs mean 80.07, SD 7.74 y</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Home-based training through software, including lower- and upper-body strengthening, balance, cardiovascular exercises, and occupational therapy (ADL training and introduction to walking aids); 3 sessions per week for 12 weeks</p></list-item><list-item><p>Supervised by professionals through the software</p></list-item></list></td><td align="left" valign="top">Home-based in-person rehabilitation, including 5-15 sessions of physiotherapy and occupational therapy</td><td align="left" valign="top">SPPB and FIM</td><td align="left" valign="top">Intervention end point: 3 months; follow-up: 9 months after the intervention</td></tr><tr><td align="left" valign="top">Latham et al [<xref ref-type="bibr" rid="ref27">27</xref>], 2014, United States</td><td align="left" valign="top">Sample size: 120 in telerehabilitation vs 112 in control group (female: 83/120 vs 77/112, respectively); age: mean 77.2, SD 10.2 y vs mean 78.9, SD 9.4 y</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>Home-based training through DVD, including strengthening and standing exercises; 3 times per week for 6 months</p></list-item><list-item><p>Supervised by professionals through telephone</p></list-item></list></td><td align="left" valign="top">Nutrition education for cardiovascular health through telephone</td><td align="left" valign="top">SPPB</td><td align="left" valign="top">Intervention end point: 6 months; follow-up: 3 months after the intervention</td></tr><tr><td align="left" valign="top">Di Monaco et al [<xref ref-type="bibr" rid="ref28">28</xref>], 2015, Italy</td><td align="left" valign="top">Sample size: 78 in telerehabilitation vs 75 in control group (female: 78/78 vs 75/75, respectively); age: mean 78.7, SD 7.2 y vs mean 79.3, SD 8.0 y</td><td align="left" valign="top"><list list-type="bullet"><list-item><p>A telephone call to check environmental hazards, behaviors in ADLs, and use of assistive devices and reinforced targeted modifications to prevent falls for 35 minutes</p></list-item></list></td><td align="left" valign="top">No intervention</td><td align="left" valign="top">BI<sup><xref ref-type="table-fn" rid="table1fn8">h</xref></sup></td><td align="left" valign="top">Intervention end point: N/A; follow-up: 5.5 months after the intervention</td></tr></tbody></table><table-wrap-foot><fn id="table1fn1"><p><sup>a</sup>TUG: timed up and go.</p></fn><fn id="table1fn2"><p><sup>b</sup>ADL: activity of daily living.</p></fn><fn id="table1fn3"><p><sup>c</sup>MBI: modified Barthel index.</p></fn><fn id="table1fn4"><p><sup>d</sup>SPPB: Short Physical Performance Battery.</p></fn><fn id="table1fn5"><p><sup>e</sup>FIM: Functional Independence Measure.</p></fn><fn id="table1fn6"><p><sup>f</sup>N/A: not applicable.</p></fn><fn id="table1fn7"><p><sup>g</sup>HHS: Harris Hip Score.</p></fn><fn id="table1fn8"><p><sup>h</sup>BI: Barthel index.</p></fn></table-wrap-foot></table-wrap></sec><sec id="s3-3"><title>Risk of Bias in the Included Studies</title><p>Four studies [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref28">28</xref>] had a low risk of bias, 3 [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref27">27</xref>] had some concerns, and 1 [<xref ref-type="bibr" rid="ref5">5</xref>] had a high risk of bias. Overall, the randomization process was the most problematic domain as 3 studies poorly described the method used [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref25">25</xref>]. The results of the methodological quality assessment are provided in <xref ref-type="fig" rid="figure2">Figure 2</xref> [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref28">28</xref>].</p><fig position="float" id="figure2"><label>Figure 2.</label><caption><p>A detailed breakdown of the methodological quality assessment for the included studies. Overall, 4 studies exhibited a low risk of bias, 3 raised some concerns, and 1 exhibited a high risk of bias [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref28">28</xref>].</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="mhealth_v14i1e77341_fig02.png"/></fig></sec><sec id="s3-4"><title>Effectiveness of Postoperative Telerehabilitation on Functional Recovery at the Intervention End Point and Follow-Up</title><p>HHS was measured in 2 studies involving a total of 156 participants at the intervention end point [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>]. Low clinical heterogeneity was observed in patient characteristics (mean age range 72-77 years; comparable baseline mean HHS between 34.9 and 43.6). However, substantial clinical heterogeneity was found regarding the duration of telerehabilitation (6 months [<xref ref-type="bibr" rid="ref5">5</xref>] vs 3 months [<xref ref-type="bibr" rid="ref22">22</xref>]). A random-effects meta-analysis yielded a statistically significant, positive result (MD 7.42, 95% CI 5.61-9.23; <italic>P</italic>&#x003C;.001; <xref ref-type="fig" rid="figure3">Figure 3</xref> [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>]) with low statistical heterogeneity (<italic>I</italic><sup>2</sup>=3%; <italic>P</italic>=.36; <xref ref-type="fig" rid="figure3">Figure 3</xref> [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>]).</p><fig position="float" id="figure3"><label>Figure 3.</label><caption><p>Forest plot of Harris Hip Score (HHS) results at the intervention end point. The analysis yielded a positive result with a mean difference of 7.42 (95% CI 5.61-9.23; <italic>P</italic>&#x003C;.001; <italic>I</italic><sup>2</sup>=3%) [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>]. IV: inverse variance.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="mhealth_v14i1e77341_fig03.png"/></fig><p>SPPB was measured in 4 studies (n=430 participants) at the intervention end point [<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref27">27</xref>]. Considerable clinical heterogeneity was observed in baseline SPPB scores (mean scores 4.71-5.9 [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref27">27</xref>] vs 2.69-3.21 [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref24">24</xref>]). Furthermore, both the duration of telerehabilitation (3 months [<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref24">24</xref>] vs 6 months [<xref ref-type="bibr" rid="ref27">27</xref>]) and the type of control intervention (telephone assessment [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref27">27</xref>] vs in-person rehabilitation [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref24">24</xref>]) varied across studies. A random-effects meta-analysis showed a significant positive result at the intervention end point (MD 1.34, 95% CI 1.14-1.55; <italic>P</italic>&#x003C;.001; <xref ref-type="fig" rid="figure4">Figure 4</xref> [<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref27">27</xref>]) with low to moderate statistical heterogeneity (<italic>I</italic><sup>2</sup>=33%; <italic>P</italic>=.21; <xref ref-type="fig" rid="figure4">Figure 4</xref> [<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref27">27</xref>]). SPPB was measured in 2 studies (n=292 participants) at follow-up [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref27">27</xref>]. In addition to the aforementioned clinical heterogeneity, great methodological heterogeneity was noted in the follow-up period (3 months [<xref ref-type="bibr" rid="ref27">27</xref>] vs 9 months after the intervention [<xref ref-type="bibr" rid="ref23">23</xref>]). The random-effects analysis remained significant at follow-up (MD 1.17, 95% CI 1.00-1.34; <italic>P</italic>&#x003C;.001; <xref ref-type="fig" rid="figure4">Figure 4</xref> [<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref27">27</xref>]) with low statistical heterogeneity (<italic>I</italic><sup>2</sup>=0%; <italic>P</italic>=.72; <xref ref-type="fig" rid="figure4">Figure 4</xref> [<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref27">27</xref>]).</p><fig position="float" id="figure4"><label>Figure 4.</label><caption><p>Forest plot of Short Physical Performance Battery (SPPB) results at the intervention end point and follow-up. The analysis yielded a positive result at the intervention end point with a mean difference of 1.34 (95% CI 1.14-1.55; <italic>P</italic>&#x003C;.001; <italic>I</italic><sup>2</sup>=33%). The analysis yielded a positive result at follow-up with a mean difference of 1.17 (95% CI 1.00-1.34; <italic>P</italic>&#x003C;.001; <italic>I</italic><sup>2</sup>=0%) [<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref27">27</xref>]. IV: inverse variance.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="mhealth_v14i1e77341_fig04.png"/></fig><p>The TUG test was measured in 4 studies (n=156 participants) at the intervention end point [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref24">24</xref>-<xref ref-type="bibr" rid="ref26">26</xref>]. Considerable clinical heterogeneity was found regarding the patient characteristics (mean age 65.7-67.3 years [<xref ref-type="bibr" rid="ref26">26</xref>] vs 75.17-82.1 years [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref25">25</xref>]; mean baseline TUG score 21.4-25.6 [<xref ref-type="bibr" rid="ref26">26</xref>] vs 39.7-45.2 [<xref ref-type="bibr" rid="ref25">25</xref>] vs 66.53-99.72 [<xref ref-type="bibr" rid="ref24">24</xref>]; data unavailable for the study by Zhang et al [<xref ref-type="bibr" rid="ref22">22</xref>]). The duration of telerehabilitation (3-6 weeks [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref26">26</xref>] vs 3 months [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref24">24</xref>]) and type of control intervention (written materials [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref26">26</xref>] vs telephone assessment [<xref ref-type="bibr" rid="ref22">22</xref>] vs in-person rehabilitation [<xref ref-type="bibr" rid="ref24">24</xref>]) also varied. A random-effects meta-analysis demonstrated a significant positive result at the intervention end point (MD &#x2013;8.45, 95% CI &#x2212;11.28 to &#x2212;5.62; <italic>P</italic>&#x003C;.001; <xref ref-type="fig" rid="figure5">Figure 5</xref>) with low statistical heterogeneity (<italic>I</italic><sup>2</sup>=0%; <italic>P</italic>=.53; <xref ref-type="fig" rid="figure5">Figure 5</xref> [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref24">24</xref>-<xref ref-type="bibr" rid="ref26">26</xref>]). The TUG test was measured in 2 studies (n=63 participants) at follow-up [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref26">26</xref>]. Low methodological heterogeneity was observed in the follow-up period (3-4 weeks after the intervention [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref26">26</xref>]) and risk of bias (low to moderate risk of bias [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref26">26</xref>]). However, due to the considerable clinical heterogeneity noted above (in patient age and baseline function), a random-effects model was applied. This analysis yielded a significant positive result at follow-up (MD &#x2212;7.66, 95% CI &#x2212;13.78 to &#x2212;1.53; <italic>P</italic>=.001; <italic>I</italic><sup>2</sup>=0%; <italic>P</italic>=.37; <xref ref-type="fig" rid="figure5">Figure 5</xref> [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref24">24</xref>-<xref ref-type="bibr" rid="ref26">26</xref>]).</p><fig position="float" id="figure5"><label>Figure 5.</label><caption><p>Forest plot of timed up and go (TUG) test results at the intervention end point and follow-up. The analysis yielded a positive result at the intervention end point with a mean difference of &#x2013;8.45 (95% CI &#x2013;11.28 to &#x2013;5.62; <italic>P</italic>&#x003C;.001; <italic>I</italic><sup>2</sup>=0%). The analysis yielded a positive result at follow-up with a mean difference of &#x2013;7.66 (95% CI &#x2013;13.78 to &#x2013;1.53; <italic>P</italic>=.01; <italic>I</italic><sup>2</sup>=0%) [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref24">24</xref>-<xref ref-type="bibr" rid="ref26">26</xref>]. IV: inverse variance.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="mhealth_v14i1e77341_fig05.png"/></fig><p>Because various BADL measurement tools were used across the included studies, SMDs were used as the effect size measure. Zhang et al [<xref ref-type="bibr" rid="ref22">22</xref>] reported BADL outcomes separately for the hip replacement and internal fixation groups. BADLs were measured in 5 studies (n=354 participants) at the intervention end point [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref25">25</xref>]. Considerable clinical heterogeneity was observed regarding patient characteristics (baseline dependence level: maximal dependence [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>] vs mild to moderate dependence [<xref ref-type="bibr" rid="ref23">23</xref>-<xref ref-type="bibr" rid="ref25">25</xref>]), duration of telerehabilitation (3 weeks [<xref ref-type="bibr" rid="ref25">25</xref>] vs 3 months [<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref24">24</xref>] vs 6 months [<xref ref-type="bibr" rid="ref5">5</xref>]), and type of control intervention (written materials [<xref ref-type="bibr" rid="ref25">25</xref>] vs telephone assessment [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>] vs in-person rehabilitation [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref24">24</xref>]). In addition, substantial methodological heterogeneity was observed in the risk of bias (high [<xref ref-type="bibr" rid="ref5">5</xref>] vs some concerns [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref25">25</xref>] vs low [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref24">24</xref>]). A random-effects meta-analysis yielded a significant positive result with high heterogeneity (SMD 1.65, 95% CI 0.78-2.51; <italic>P</italic>&#x003C;.001; <italic>I</italic><sup>2</sup>=91%; <italic>P</italic>&#x003C;.001; <xref ref-type="fig" rid="figure6">Figure 6</xref> [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref25">25</xref>]). Subgroup analyses were conducted based on baseline dependence level, duration of telerehabilitation, and type of control intervention. For studies involving patients with a high baseline dependence level [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>], the analysis showed a positive result with high heterogeneity (SMD 1.87, 95% CI 0.59-3.16; <italic>P</italic>=.004; <italic>I</italic><sup>2</sup>=89%; <italic>P</italic>&#x003C;.001; <xref ref-type="fig" rid="figure6">Figure 6</xref> [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref25">25</xref>]). For studies with a lower baseline dependence level [<xref ref-type="bibr" rid="ref23">23</xref>-<xref ref-type="bibr" rid="ref25">25</xref>], the result was also positive with high heterogeneity (SMD 1.42, 95% CI 0.04-2.81; <italic>P</italic>=.04; <italic>I</italic><sup>2</sup>=94%; <italic>P</italic>&#x003C;.001; <xref ref-type="fig" rid="figure6">Figure 6</xref> [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref25">25</xref>]). Subgroup analysis by duration of telerehabilitation was not possible due to an insufficient number of studies. For studies with telephone-based assessment as a control intervention [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>], the result was positive with high heterogeneity (SMD 1.87, 95% CI 0.59-3.16; <italic>P</italic>=.004; <italic>I</italic><sup>2</sup>=89%; <italic>P</italic>&#x003C;.001; <xref ref-type="fig" rid="figure6">Figure 6</xref> [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref25">25</xref>]). For studies with in-person rehabilitation as the control [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref24">24</xref>], the result was similarly positive with high heterogeneity (SMD 1.90, 95% CI 0.16-3.63; <italic>P</italic>=.03; <italic>I</italic><sup>2</sup>=95%; <italic>P</italic>&#x003C;.001; <xref ref-type="fig" rid="figure6">Figure 6</xref> [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref25">25</xref>]). A sensitivity analysis was conducted by (1) excluding 2 studies with intervention durations shorter [<xref ref-type="bibr" rid="ref25">25</xref>] or longer [<xref ref-type="bibr" rid="ref5">5</xref>] than 3 months and (2) excluding 1 study with a high risk of bias [<xref ref-type="bibr" rid="ref5">5</xref>]. Pooling the 3 remaining studies with a 3-month intervention duration [<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref24">24</xref>] using a random-effects model yielded a positive result with low statistical heterogeneity (SMD 1.13, 95% CI 0.76-1.50; <italic>P</italic>&#x003C;.001; <italic>I</italic><sup>2</sup>=0%; <italic>P</italic>=.82; <xref ref-type="fig" rid="figure6">Figure 6</xref> [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref25">25</xref>]). Pooling the 4 studies with low to moderate risk of bias [<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref25">25</xref>] yielded a positive result with high heterogeneity (SMD 1.36, 95% CI 0.52-2.21; <italic>P</italic>=.002; <italic>I</italic><sup>2</sup>=88%; <italic>P</italic>&#x003C;.001). BADLs were measured in 3 studies (n=257 participants) at follow-up [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref28">28</xref>]. Considerable clinical heterogeneity was observed regarding baseline dependence level (mild to moderate dependence [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref25">25</xref>] vs minimal dependence [<xref ref-type="bibr" rid="ref28">28</xref>]), duration of telerehabilitation (2.5-3 weeks [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref28">28</xref>] vs 12 weeks [<xref ref-type="bibr" rid="ref23">23</xref>]), delivery mode of telerehabilitation (telephone based [<xref ref-type="bibr" rid="ref28">28</xref>] vs software based [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref25">25</xref>]), and type of control intervention (no intervention [<xref ref-type="bibr" rid="ref28">28</xref>] vs in-person rehabilitation [<xref ref-type="bibr" rid="ref23">23</xref>] vs written materials [<xref ref-type="bibr" rid="ref25">25</xref>]). Moreover, substantial methodological heterogeneity was found in the follow-up period (3 weeks [<xref ref-type="bibr" rid="ref25">25</xref>] vs 5.5 months [<xref ref-type="bibr" rid="ref28">28</xref>] vs 9 months [<xref ref-type="bibr" rid="ref23">23</xref>] after the intervention). A random-effects model yielded a positive result with moderate heterogeneity at follow-up (SMD 0.43, 95% CI 0.05-0.81; <italic>P</italic>=.03; <italic>I</italic><sup>2</sup>=48%; <italic>P</italic>=.15; <xref ref-type="fig" rid="figure7">Figure 7</xref> [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref28">28</xref>]). A sensitivity analysis excluded 1 study [<xref ref-type="bibr" rid="ref28">28</xref>] that differed substantially from the others in design (baseline dependence level, type of telerehabilitation, and type of control intervention). A random-effects model for the remaining 2 studies [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref25">25</xref>] yielded a positive result with low heterogeneity (SMD 0.66, 95% CI 0.26-1.05; <italic>P</italic>=.001; <italic>I</italic><sup>2</sup>=0%; <italic>P</italic>=.41; <xref ref-type="fig" rid="figure7">Figure 7</xref> [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref28">28</xref>]).</p><fig position="float" id="figure6"><label>Figure 6.</label><caption><p>Forest plot of basic activity of daily living (BADL) results at the intervention end point. The analysis yielded a positive result at the intervention end point with a standardized mean difference of 1.65 (95% CI 0.78-2.51; <italic>P</italic>&#x003C;.001) and high heterogeneity (<italic>I</italic><sup>2</sup>=91%). Subgroup analyses were conducted based on baseline dependence level and type of control intervention. A sensitivity analysis was conducted by excluding a study with a high risk of bias [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref22">22</xref>-<xref ref-type="bibr" rid="ref25">25</xref>]. IV: inverse variance.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="mhealth_v14i1e77341_fig06.png"/></fig><fig position="float" id="figure7"><label>Figure 7.</label><caption><p>Forest plot of basic activity of daily living (BADL) results at follow-up. The analysis yielded a positive result at follow-up with a standardized mean difference of 0.43 (95% CI 0.05-0.81; <italic>P</italic>=.03; <italic>I</italic><sup>2</sup>=48%). A sensitivity analysis was conducted by excluding a study with a different study design from the others [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref28">28</xref>]. IV: inverse variance.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="mhealth_v14i1e77341_fig07.png"/></fig></sec></sec><sec id="s4" sec-type="discussion"><title>Discussion</title><sec id="s4-1"><title>Principal Findings</title><p>Our review found that postoperative telerehabilitation was effective in improving short- and long-term hip function, functional mobility, and ability to perform BADLs in patients with hip fractures compared to conventional rehabilitation. However, current evidence was weak due to the limited number and insufficient quality of the included studies and the heterogeneity across studies.</p><p>Our findings align with previous evidence that telerehabilitation is beneficial to short-term recovery of functional mobility and ability to perform BADLs at posttreatment compared to usual care [<xref ref-type="bibr" rid="ref12">12</xref>]. Moreover, our review found that hip function was also improved after telerehabilitation. In addition, our findings revealed the effect of telerehabilitation on long-term recovery (3 weeks to 9 months after the intervention) in functional mobility and the ability to perform BADLs. The effectiveness in improving BADLs showed substantial heterogeneity across the included studies in the postintervention analysis. Although subgroup analyses were conducted based on the type of control intervention and the baseline dependence level, they failed to reduce the heterogeneity. A potential source of heterogeneity may be the duration of telerehabilitation as the statistical heterogeneity decreased dramatically when 2 studies with telerehabilitation shorter (3 weeks) [<xref ref-type="bibr" rid="ref25">25</xref>] and longer (6 months) [<xref ref-type="bibr" rid="ref5">5</xref>] than 3 months were excluded. Another potential source of heterogeneity may be differences in adherence to the telerehabilitation programs. Although only 2 of the 5 studies in the BADL analysis reported adherence rates for telerehabilitation, the substantial difference (87% [<xref ref-type="bibr" rid="ref25">25</xref>] vs 15% [<xref ref-type="bibr" rid="ref24">24</xref>]) suggests considerable variability in compliance across studies.</p><p>This systematic review revealed that telerehabilitation strategies, including exercises for strengthening the lower extremities, balance, coordination, stretching, and BADL training, introduction of walking aids, and safety education are commonly used for patients with hip fractures. According to clinical practice guidelines, postoperative progressive resistance exercises and balance training are strongly recommended, and BADL training and complication prevention are suggested for older patients with hip fractures [<xref ref-type="bibr" rid="ref29">29</xref>]. However, it is essential to standardize these training programs to mitigate the risk of adverse events [<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref31">31</xref>].</p><p>Regarding the delivery mode of telerehabilitation, most studies used software- or mobile app&#x2013;based telerehabilitation with remote supervision by professionals, and only 2 studies conducted before 2015 used DVD-based or telephone-based telerehabilitation. Recently, the application of virtual reality has become an increasingly common approach in telerehabilitation, with superior long-term benefits for patients with total knee replacements compared with traditional rehabilitation [<xref ref-type="bibr" rid="ref32">32</xref>]. Although all these remote rehabilitation approaches could facilitate adherence to postoperative management, reduce costs, and decrease the burden on therapists and caregivers, the efficacy of different delivery strategies could vary. Future studies are needed to compare the cost-effectiveness ratio between different delivery modes of telerehabilitation.</p><p>Our findings may have several clinical implications. First, substantial clinically important improvements in functional mobility, as measured using the SPPS [<xref ref-type="bibr" rid="ref33">33</xref>] and TUG test [<xref ref-type="bibr" rid="ref34">34</xref>,<xref ref-type="bibr" rid="ref35">35</xref>], were observed following telerehabilitation compared to usual care at the postintervention and follow-up time points. However, the overall improvement in HHS (7.35 points) fell below the minimal clinically important improvement threshold (15.9-18 points) [<xref ref-type="bibr" rid="ref36">36</xref>]. For BADLs, a large short-term effect size (SMD 1.65) was found, but this decreased to a small to moderate effect at the long-term follow-up (SMD 0.43). Furthermore, no included studies demonstrated a clinically relevant improvement for BADLs (21 points on the FIM [<xref ref-type="bibr" rid="ref37">37</xref>] and 9.8 points on the BI [<xref ref-type="bibr" rid="ref38">38</xref>]). These findings indicate that telerehabilitation may be more beneficial for functional mobility than for hip function or BADLs. Second, we noted that most included studies were conducted in countries with established research environments (Israel, Spain, Portugal, and the United States), with China being the only included country with an emerging research landscape. Therefore, the generalizability of telerehabilitation requires further investigation, specifically in terms of its feasibility and effectiveness in low- and middle-income countries. Third, the included studies exhibited variable follow-up periods (3 weeks to 9 months), which impedes the investigation of long-term effects. Future studies could adopt a more standardized follow-up schedule (eg, every 3 months after the intervention). Fourth, adherence to telerehabilitation was poorly reported in the included studies, leaving its influence on the effect size unclear. As a key proposed benefit of telerehabilitation is the facilitation of prolonged rehabilitation training&#x2014;and studies have demonstrated higher compliance in telerehabilitation groups, potentially leading to greater improvement [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref26">26</xref>]&#x2014;detailed adherence data are crucial for interpreting effectiveness. Future studies should report adherence and compliance rates in detail and develop effective supervision approaches to ensure the efficacy of telerehabilitation.</p></sec><sec id="s4-2"><title>Limitations</title><p>This study has several limitations. First, it only included literature published in English, which may have omitted relevant evidence from articles published in other languages, potentially introducing language bias and limiting the generalizability of the findings. Second, the small number of included studies and the substantial heterogeneity observed influenced the strength of the evidence. Third, no statistical analysis for publication bias was conducted due to the small number of included studies.</p></sec><sec id="s4-3"><title>Conclusions</title><p>Telerehabilitation is effective for short- and long-term functional recovery in postoperative patients with hip fractures compared to conventional rehabilitation. However, the evidence is weak due to the limited number of included studies and the high heterogeneity across studies. Future high-quality studies with larger sample sizes are needed to investigate the effectiveness of telerehabilitation. These studies should report the intervention strategies, delivery modes, and adherence rates of interventions in detail; incorporate comprehensive outcome measures for hip function (eg, HHS), functional mobility (eg, SPPS and TUG test), and ability to perform BADLs (eg, BI, MBI, and FIM); and apply a relatively standard follow-up period to investigate the long-term effect of telerehabilitation.</p></sec></sec></body><back><notes><sec><title>Funding</title><p>This work was supported by the Shenzhen Science and Technology Program (JCYJ20240813145301003 awarded to XW).</p></sec></notes><fn-group><fn fn-type="conflict"><p>None declared.</p></fn></fn-group><glossary><title>Abbreviations</title><def-list><def-item><term id="abb1">BADL</term><def><p>basic activity of daily living</p></def></def-item><def-item><term id="abb2">BI</term><def><p>Barthel index</p></def></def-item><def-item><term id="abb3">FIM</term><def><p>Functional Independence Measure</p></def></def-item><def-item><term id="abb4">HHS</term><def><p>Harris Hip Score</p></def></def-item><def-item><term id="abb5">MBI</term><def><p>modified Barthel index</p></def></def-item><def-item><term id="abb6">MD</term><def><p>mean difference</p></def></def-item><def-item><term id="abb7">MeSH</term><def><p>Medical Subject Headings</p></def></def-item><def-item><term id="abb8">PRISMA</term><def><p>Preferred Reporting Items for Systematic Reviews and Meta-Analyses</p></def></def-item><def-item><term id="abb9">SMD</term><def><p>standardized mean difference</p></def></def-item><def-item><term id="abb10">SPPB</term><def><p>Short Physical Performance Battery</p></def></def-item><def-item><term id="abb11">TUG</term><def><p>timed up and go</p></def></def-item></def-list></glossary><ref-list><title>References</title><ref id="ref1"><label>1</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Sing</surname><given-names>CW</given-names> </name><name 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