@Article{info:doi/10.2196/11158, author="Han, Min Kyu and Cho, Belong and Kwon, Hyuktae and Son, Ki Young and Lee, Hyejin and Lee, Joo Kyung and Park, Jinho", title="A Mobile-Based Comprehensive Weight Reduction Program for the Workplace (Health-On): Development and Pilot Study", journal="JMIR Mhealth Uhealth", year="2019", month="Nov", day="4", volume="7", number="11", pages="e11158", keywords="weight loss programs; smartphone; mobile phone; workplaces; obesity; obesity management", abstract="Background: There is a growing interest in mobile technology for obesity management. Despite the known effectiveness of workplace-based weight loss programs, there are few studies on mobile phone--delivered interventions. Objective: This study aimed to develop and verify an integrated and personalized mobile technology--based weight control program, named Health-On, optimized for workplaces. Methods: A weight reduction algorithm was developed for calorie prescription, continuous monitoring, periodic feedback and reevaluation, goal resetting, and offline intervention with behavior-changing strategies. A total of 30 obese volunteers (body mass index ≥25 kg/m2) participated in the 12-week Health-On pilot program. The primary outcome was weight reduction, and secondary outcomes were improved anthropometric measures, metabolic profiles, and fat computed tomography measures, all assessed pre- and postintervention. Results: Health-On incorporated proprietary algorithms and several strategies intended to maximize adherence, using compatible online and offline interventions. The mean weight of 30 participants decreased by 5.8{\%}, and median weight also decreased from 81.3 kg (interquartile range [IQR] 77.1-87.8) before intervention to 76.6 kg (IQR 70.8-79.5) after the 12-week intervention period (P<.001). The metabolic profiles and fat measures (blood pressure, glycosylated hemoglobin, total cholesterol, triglyceride, high-density lipoprotein, low-density lipoprotein, alanine aminotransferase, and visceral and subcutaneous adipose tissue; P<.05) also improved significantly. Conclusions: In this single-group evaluation of 30 participants before and after the Health-On program, body weight decreased and metabolic profiles and fat measures improved. Follow-up studies are needed to assess effectiveness and long-term adherence. ", issn="2291-5222", doi="10.2196/11158", url="https://mhealth.jmir.org/2019/11/e11158", url="https://doi.org/10.2196/11158", url="http://www.ncbi.nlm.nih.gov/pubmed/31682576" }