%0 Journal Article %@ 2291-5222 %I JMIR Publications Inc. %V 1 %N 2 %P e17 %T A Text Message Delivered Smoking Cessation Intervention: The Initial Trial of TXT-2-Quit: Randomized Controlled Trial %A Bock,Beth %A Heron,Kristin %A Jennings,Ernestine %A Morrow,Kathleen %A Cobb,Victoria %A Magee,Joshua %A Fava,Joseph %A Deutsch,Christopher %A Foster,Robert %+ Alpert Medical School, Brown University, Centers for Behavioral and Preventive Medicine, The Miriam Hospital, 164 Summit Avenue, Providence, RI, 02906, United States, 1 401 793 8020, Bbock@lifespan.org %K smoking cessation %K tobacco %K texting, text messaging %K mobile health %K mHealth %K health communications %D 2013 %7 30.07.2013 %9 Original Paper %J JMIR Mhealth Uhealth %G English %X Background: Mobile technology offers the potential to deliver health-related interventions to individuals who would not otherwise present for in-person treatment. Text messaging (short message service, SMS), being the most ubiquitous form of mobile communication, is a promising method for reaching the most individuals. Objective: The goal of the present study was to evaluate the feasibility and preliminary efficacy of a smoking cessation intervention program delivered through text messaging. Methods: Adult participants (N=60, age range 18-52 years) took part in a single individual smoking cessation counseling session, and were then randomly assigned to receive either daily non-smoking related text messages (control condition) or the TXT-2-Quit (TXT) intervention. TXT consisted of automated smoking cessation messages tailored to individual’s stage of smoking cessation, specialized messages provided on-demand based on user requests for additional support, and a peer-to-peer social support network. Generalized estimating equation analysis was used to assess the primary outcome (7-day point-prevalence abstinence) using a 2 (treatment groups)×3 (time points) repeated measures design across three time points: 8 weeks, 3 months, and 6 months. Results: Smoking cessation results showed an overall significant group difference in 7-day point prevalence abstinence across all follow-up time points. Individuals given the TXT intervention, with higher odds of 7-day point prevalence abstinence for the TXT group compared to the Mojo group (OR=4.52, 95% CI=1.24, 16.53). However, individual comparisons at each time point did not show significant between-group differences, likely due to reduced statistical power. Intervention feasibility was greatly improved by switching from traditional face-to-face recruitment methods (4.7% yield) to an online/remote strategy (41.7% yield). Conclusions: Although this study was designed to develop and provide initial testing of the TXT-2-Quit system, these initial findings provide promising evidence that a text-based intervention can be successfully implemented with a diverse group of adult smokers. Trial Registration: ClinicalTrials.gov: NCT01166464; http://clinicaltrials.gov/ct2/show/NCT01166464 (Archived by WebCite at http://www.webcitation.org/6IOE8XdE0). %M 25098502 %R 10.2196/mhealth.2522 %U http://mhealth.jmir.org/2013/2/e17/ %U https://doi.org/10.2196/mhealth.2522 %U http://www.ncbi.nlm.nih.gov/pubmed/25098502