%0 Journal Article %@ 2291-5222 %I JMIR Publications %V 7 %N 11 %P e11158 %T A Mobile-Based Comprehensive Weight Reduction Program for the Workplace (Health-On): Development and Pilot Study %A Han,Min Kyu %A Cho,Belong %A Kwon,Hyuktae %A Son,Ki Young %A Lee,Hyejin %A Lee,Joo Kyung %A Park,Jinho %+ Department of Family Medicine, Seoul National University Hospital, 101 Daehak-ro Jongno-gu, Seoul, 03080, Republic of Korea, 82 2 2072 0865, kkolzzi0@gmail.com %K weight loss programs %K smartphone %K mobile phone %K workplaces %K obesity %K obesity management %D 2019 %7 4.11.2019 %9 Original Paper %J JMIR Mhealth Uhealth %G English %X Background: There is a growing interest in mobile technology for obesity management. Despite the known effectiveness of workplace-based weight loss programs, there are few studies on mobile phone–delivered interventions. Objective: This study aimed to develop and verify an integrated and personalized mobile technology–based weight control program, named Health-On, optimized for workplaces. Methods: A weight reduction algorithm was developed for calorie prescription, continuous monitoring, periodic feedback and reevaluation, goal resetting, and offline intervention with behavior-changing strategies. A total of 30 obese volunteers (body mass index ≥25 kg/m2) participated in the 12-week Health-On pilot program. The primary outcome was weight reduction, and secondary outcomes were improved anthropometric measures, metabolic profiles, and fat computed tomography measures, all assessed pre- and postintervention. Results: Health-On incorporated proprietary algorithms and several strategies intended to maximize adherence, using compatible online and offline interventions. The mean weight of 30 participants decreased by 5.8%, and median weight also decreased from 81.3 kg (interquartile range [IQR] 77.1-87.8) before intervention to 76.6 kg (IQR 70.8-79.5) after the 12-week intervention period (P<.001). The metabolic profiles and fat measures (blood pressure, glycosylated hemoglobin, total cholesterol, triglyceride, high-density lipoprotein, low-density lipoprotein, alanine aminotransferase, and visceral and subcutaneous adipose tissue; P<.05) also improved significantly. Conclusions: In this single-group evaluation of 30 participants before and after the Health-On program, body weight decreased and metabolic profiles and fat measures improved. Follow-up studies are needed to assess effectiveness and long-term adherence. %M 31682576 %R 10.2196/11158 %U https://mhealth.jmir.org/2019/11/e11158 %U https://doi.org/10.2196/11158 %U http://www.ncbi.nlm.nih.gov/pubmed/31682576