TY  - JOUR
AU  - Mach, Markus
AU  - Watzal, Victoria
AU  - Hasan, Waseem
AU  - Andreas, Martin
AU  - Winkler, Bernhard
AU  - Weiss, Gabriel
AU  - Strouhal, Andreas
AU  - Adlbrecht, Christopher
AU  - Delle Karth, Georg
AU  - Grabenwöger, Martin
PY  - 2020
DA  - 2020/10/15
TI  - Fitness-Tracker Assisted Frailty-Assessment Before Transcatheter Aortic Valve Implantation: Proof-of-Concept Study
JO  - JMIR Mhealth Uhealth
SP  - e19227
VL  - 8
IS  - 10
KW  - frailty
KW  - activity
KW  - fitness
KW  - tracker
KW  - transcatheter aortic valve implantation
KW  - transcatheter aortic valve repair
AB  - Background: While transcatheter aortic valve replacement (TAVR) has revolutionized the treatment of aortic valve stenosis, wearable health-monitoring devices are gradually transforming digital patient care. Objective: The aim of this study was to develop a simple, efficient, and economical method for preprocedural frailty assessment based on parameters measured by a wearable health-monitoring device. Methods: In this prospective study, we analyzed data of 50 consecutive patients with mean (SD) age of 77.5 (5.1) years and a median (IQR) European system for cardiac operative risk evaluation (EuroSCORE) II of 3.3 (4.1) undergoing either transfemoral or transapical TAVR between 2017 and 2018. Every patient was fitted with a wrist-worn health-monitoring device (Garmin Vivosmart 3) for 1 week prior to the procedure. Twenty different parameters were measured, and threshold levels for the 3 most predictive categories (ie, step count, heart rate, and preprocedural stress) were calculated. Patients were assigned 1 point per category for exceeding the cut-off value and were then classified into 4 stages (no, borderline, moderate, and severe frailty). Furthermore, the FItness-tracker assisted Frailty-Assessment Score (FIFA score) was compared with the scores of the preprocedural gait speed category derived from the 6-minute walk test (GSC-6MWT) and the Edmonton Frail Scale classification (EFS-C). The primary study endpoint was hospital mortality. Results: The overall preprocedural stress level (P=.02), minutes of high stress per day (P=.02), minutes of rest per day (P=.045), and daily heart rate maximum (P=.048) as single parameters were the strongest predictors of hospital mortality. When comparing the different frailty scores, the FIFA score demonstrated the greatest predictive power for hospital mortality (FIFA area under the curve [AUC] 0.844, CI 0.656-1.000; P=.048; GSC-6MWT AUC 0.671, CI 0.487-0.855; P=.42; EFS-C AUC 0.636, CI 0.254-1.000; P=.44). Conclusions: This proof-of-concept study demonstrates the strong predictive performance of the FIFA score compared to that of the conventional frailty assessments. 
SN  - 2291-5222
UR  - https://mhealth.jmir.org/2020/10/e19227
UR  - https://doi.org/10.2196/19227
UR  - http://www.ncbi.nlm.nih.gov/pubmed/33055057
DO  - 10.2196/19227
ID  - info:doi/10.2196/19227
ER  -