TY - JOUR AU - Zhao, Liuhong AU - Chen, Jingfen AU - Lan, Liuying AU - Deng, Ni AU - Liao, Yan AU - Yue, Liqun AU - Chen, Innie AU - Wen, Shi Wu AU - Xie, Ri-hua PY - 2021 DA - 2021/10/7 TI - Effectiveness of Telehealth Interventions for Women With Postpartum Depression: Systematic Review and Meta-analysis JO - JMIR Mhealth Uhealth SP - e32544 VL - 9 IS - 10 KW - telehealth KW - postpartum depression KW - anxiety KW - meta-analysis AB - Background: Postpartum depression (PPD) is a prevalent mental health problem with serious adverse consequences for affected women and their infants. Clinical trials have found that telehealth interventions for women with PPD result in increased accessibility and improved treatment effectiveness. However, no comprehensive synthesis of evidence from clinical trials by systematic review has been conducted. Objective: The aim of this study is to evaluate the effectiveness of telehealth interventions in reducing depressive symptoms and anxiety in women with PPD. To enhance the homogeneity and interpretability of the findings, this systematic review focuses on PPD measured by the Edinburgh Postnatal Depression Scale (EPDS). Methods: PubMed, The Cochrane Library, CINAHL, PsycINFO, CNKI, and Wanfang were electronically searched to identify randomized controlled trials (RCTs) on the effectiveness of telehealth interventions for women with PPD from inception to February 28, 2021. Data extraction and quality assessment were performed independently by two researchers. The quality of included studies was assessed using the Cochrane risk-of-bias tool, and meta-analysis was performed using RevMan 5.4 software. Results: Following the search, 9 RCTs with a total of 1958 women with PPD were included. The EPDS (mean difference=–2.99, 95% CI –4.52 to –1.46; P<.001) and anxiety (standardized mean difference=–0.39, 95% CI –0.67 to –0.12; P=.005) scores were significantly lower in the telehealth group compared with the control group. Significant subgroup differences were found in depressive symptoms according to the severity of PPD, telehealth technology, specific therapy, and follow-up time (P<.001). Conclusions: Telehealth interventions could effectively reduce the symptoms of depression and anxiety in women with PPD. However, better designed and more rigorous large-scale RCTs targeting specific therapies are needed to further explore the potential of telehealth interventions for PPD. Trial Registration: PROSPERO CRD42021258541; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=258541 SN - 2291-5222 UR - https://mhealth.jmir.org/2021/10/e32544 UR - https://doi.org/10.2196/32544 UR - http://www.ncbi.nlm.nih.gov/pubmed/34617909 DO - 10.2196/32544 ID - info:doi/10.2196/32544 ER -