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Impact of Removing Nonprescription Codeine in Australia: Protocol for a Prospective Cohort Study

Impact of Removing Nonprescription Codeine in Australia: Protocol for a Prospective Cohort Study

In a Web survey of codeine consumers by Nielsen et al [76], daily codeine use had a mean of 68 (SD 72) mg. These power calculations suggest that there would be sufficient power to identify a drop from 68 to 53 mg per day in the daily codeine dose variable as statistically significant, assuming this range of correlations and this standard deviation of scores. This is a little more than a single 12.8 mg nonprescription (OTC) codeine tablet, and therefore, is of an appropriate magnitude for this study.

Jacqui McCoy, Suzanne Nielsen, Raimondo Bruno

JMIR Res Protoc 2020;9(3):e15540