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Deciphering the Efficacy and Mechanisms of Chinese Herbal Medicine for Diabetic Kidney Disease by Integrating Web-Based Biochemical Databases and Real-World Clinical Data: Retrospective Cohort Study

Deciphering the Efficacy and Mechanisms of Chinese Herbal Medicine for Diabetic Kidney Disease by Integrating Web-Based Biochemical Databases and Real-World Clinical Data: Retrospective Cohort Study

Moreover, some medications may be used to relieve proteinuria and ameliorate renal dysfunction, such as Astragalus membranaceus (Fisch.) and Liu-Wei-Di-Huang-Wan [29-31]. The potential mechanisms include anti-inflammation, antifibrosis, antioxidation, immunomodulation, and regulation of podocyte dysfunction [30-36]. Besides, some CHMs have been found to have effects on tubular cell cycle modulation [37].

Chien-Wei Wu, Hsing-Yu Chen, Ching-Wei Yang, Yu-Chun Chen

JMIR Med Inform 2021;9(5):e27614

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