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Exploring the Impact of the Multimodal CAPABLE eHealth Intervention on Health-Related Quality of Life in Patients With Melanoma Undergoing Immune-Checkpoint Inhibition: Prospective Pilot Study

Exploring the Impact of the Multimodal CAPABLE eHealth Intervention on Health-Related Quality of Life in Patients With Melanoma Undergoing Immune-Checkpoint Inhibition: Prospective Pilot Study

Briefly, participants included in the study were provided with the CAPABLE mobile app and a multisensorial smartwatch (ASUS Vivo Watch 5 HC-B0) during the first 6 months of treatment with ICIs. The mobile app consisted of 3 main components; first, facilitating symptom and mental well-being monitoring, second, providing educational material, and finally, providing well-being interventions through goal setting and demonstrating the well-being intervention activity through a video or text and figures.

Itske Fraterman, Lucia Sacchi, Henk Mallo, Valentina Tibollo, Savannah Lucia Catherina Glaser, Stephanie Medlock, Ronald Cornet, Matteo Gabetta, Vitali Hisko, Vadzim Khadakou, Ella Barkan, Laura Del Campo, David Glasspool, Alexandra Kogan, Giordano Lanzola, Roy Leizer, Manuel Ottaviano, Mor Peleg, Konrad Śniatała, Aneta Lisowska, Szymon Wilk, Enea Parimbelli, Silvana Quaglini, Mimma Rizzo, Laura Deborah Locati, Annelies Boekhout, Lonneke V van de Poll-Franse, Sofie Wilgenhof

JMIR Cancer 2025;11:e58938

An eHealth App (CAPABLE) Providing Symptom Monitoring, Well-Being Interventions, and Educational Material for Patients With Melanoma Treated With Immune Checkpoint Inhibitors: Protocol for an Exploratory Intervention Trial

An eHealth App (CAPABLE) Providing Symptom Monitoring, Well-Being Interventions, and Educational Material for Patients With Melanoma Treated With Immune Checkpoint Inhibitors: Protocol for an Exploratory Intervention Trial

well-being) [28] Walking in nature (goals: improve sleep and insomnia, mental well-being, physical well-being) [28] Breathing exercises and mindfulness (goals: improve sleep and insomnia, mental well-being) Imagery meditation (goals: improve sleep and insomnia, mental well-being) [52] Photo diary (goals: mental well-being, accepting the cancer journey) [53] Gratitude journal (goals: mental well-being, accepting the cancer journey) [54,55] Patients will also be provided with a smartwatch (the ASUS Vivo Watch 5 HC-B05

Itske Fraterman, Barbara M Wollersheim, Valentina Tibollo, Savannah Lucia Catherina Glaser, Stephanie Medlock, Ronald Cornet, Matteo Gabetta, Vitali Gisko, Ella Barkan, Nicola di Flora, David Glasspool, Alexandra Kogan, Giordano Lanzola, Roy Leizer, Henk Mallo, Manuel Ottaviano, Mor Peleg, Lonneke V van de Poll-Franse, Nicole Veggiotti, Konrad Śniatała, Szymon Wilk, Enea Parimbelli, Silvana Quaglini, Mimma Rizzo, Laura Deborah Locati, Annelies Boekhout, Lucia Sacchi, Sofie Wilgenhof

JMIR Res Protoc 2023;12:e49252