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Mobile Therapeutic Attention for Treatment-Resistant Schizophrenia (m-RESIST) Solution for Improving Clinical and Functional Outcomes in Treatment-Resistant Schizophrenia: Prospective, Multicenter Efficacy Study

Mobile Therapeutic Attention for Treatment-Resistant Schizophrenia (m-RESIST) Solution for Improving Clinical and Functional Outcomes in Treatment-Resistant Schizophrenia: Prospective, Multicenter Efficacy Study

In this study, the intervention involved patients and their caregivers, and the main actors involved in the deployment of the m-RESIST solution were psychiatrists, psychologists, and case managers. The key aim of the m-RESIST solution was to engage patients with TRS, together with their caregivers, in therapeutic processes, and empower them to enable their self-management.

Jussi Seppälä, Eva Grasa, Anna Alonso-Solis, Alexandra Roldan-Bejarano, Marianne Haapea, Matti Isohanni, Jouko Miettunen, Johanna Caro Mendivelso, Cari Almazán, Katya Rubinstein, Asaf Caspi, Zolt Unoka, Kinga Farkas, Elisenda Reixach, Jesus Berdun, Judith Usall, Susana Ochoa, Iluminada Corripio, Erika Jääskeläinen, m-Resist Group

JMIR Hum Factors 2025;12:e67659

Machine Learning Model for Predicting Coronary Heart Disease Risk: Development and Validation Using Insights From a Japanese Population–Based Study

Machine Learning Model for Predicting Coronary Heart Disease Risk: Development and Validation Using Insights From a Japanese Population–Based Study

To compare differences in patient characteristics based on CHD incidence (yes or no), we used various statistical tests including 2-tailed Student t tests, Mann‒Whitney U tests, or chi-square tests, as appropriate. Feature selection was conducted in a stepwise manner to ensure that only the most relevant variables were included in the predictive models. Initially, variables with more than 30% missing data were excluded to avoid potential bias from imputation.

Thien Vu, Yoshihiro Kokubo, Mai Inoue, Masaki Yamamoto, Attayeb Mohsen, Agustin Martin-Morales, Research Dawadi, Takao Inoue, Jie Ting Tay, Mari Yoshizaki, Naoki Watanabe, Yuki Kuriya, Chisa Matsumoto, Ahmed Arafa, Yoko M Nakao, Yuka Kato, Masayuki Teramoto, Michihiro Araki

JMIR Cardio 2025;9:e68066

Machine Learning Clinical Decision Support for Interdisciplinary Multimodal Chronic Musculoskeletal Pain Treatment: Prospective Pilot Study of Patient Assessment and Prognostic Profile Validation

Machine Learning Clinical Decision Support for Interdisciplinary Multimodal Chronic Musculoskeletal Pain Treatment: Prospective Pilot Study of Patient Assessment and Prognostic Profile Validation

Profile accuracy: H=high, M=medium, L=low. AUC: area under the curve; M: mixed; N: negative; P: positive; TPR: true-positive rate; TNR: true-negative rate. The above summary (Figure 2) presents results for all pilot study patients to show performance and overall results. However, the individual prognostic patient profile as used in IMPT clinical assessment provides clearly presented summary results for each patient.

Fredrick Zmudzki, Rob J E M Smeets, Jan S Groenewegen, Erik van der Graaff

JMIR Rehabil Assist Technol 2025;12:e65890