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Prevalence of Multiple Chronic Conditions Among Adults in the All of Us Research Program: Exploratory Analysis

Prevalence of Multiple Chronic Conditions Among Adults in the All of Us Research Program: Exploratory Analysis

Moreover, research suggests that more contemporary generations of adults have a greater MCC burden and are diagnosed with MCC at earlier ages than previous generations [6]. Estimation of the prevalence of MCC throughout all stages of adulthood is a critical reflection of the MCC burden; it is important to examine the prevalence of MCC broadly using regularly updated data sources to inform targeted prevention and management strategies and resource prioritization.

Xintong Li, Caitlin Dreisbach, Carolina M Gustafson, Komal Patel Murali, Theresa A Koleck

JMIR Form Res 2025;9:e69138

Augmenting Engagement in Decentralized Clinical Trials for Atrial Fibrillation: Development and Implementation of a Programmatic Architecture

Augmenting Engagement in Decentralized Clinical Trials for Atrial Fibrillation: Development and Implementation of a Programmatic Architecture

Here we present the design and architecture of a remote mobile health program. We describe a program that uses a smartphone-based intervention to augment the self-management of AF. The intervention incorporates a relational agent [21]—an animated health educator that uses synthetic speech and conversational gestures, such as hand movements, gaze shifts, natural pauses, and emphatic facial expressions to simulate face-to-face counseling—in conjunction with a mobile heart rhythm sensor.

Toluwa Daniel Omole, Andrew Mrkva, Danielle Ferry, Erin Shepherd, Jessica Caratelli, Noah Davis, Richmond Akatue, Timothy Bickmore, Michael K Paasche-Orlow, Jared W Magnani

JMIR Cardio 2025;9:e66436

Digital Integrated Interventions for Comorbid Depression and Substance Use Disorder: Narrative Review and Content Analysis

Digital Integrated Interventions for Comorbid Depression and Substance Use Disorder: Narrative Review and Content Analysis

(computer, smartphone, internet, and text message) outside of the traditional F2 F therapy setting; and (4) the article was written in English as a peer-reviewed journal article.

Geneva K Jonathan, Qiuzuo Guo, Heyli Arcese, A Eden Evins, Sabine Wilhelm

JMIR Ment Health 2025;12:e67670

A Brief Video-Based Intervention to Improve Digital Health Literacy for Individuals With Bipolar Disorder: Intervention Development and Results of a Single-Arm Quantitative Pilot Study

A Brief Video-Based Intervention to Improve Digital Health Literacy for Individuals With Bipolar Disorder: Intervention Development and Results of a Single-Arm Quantitative Pilot Study

Ideally, clinicians would play a role in referring individuals with BD to credible, safe, and engaging apps, given their role as a trusted information source [9,17]. In practice, a web-based survey of health care providers found that only 50% had discussed or recommended smartphone apps to patients with BD [18].

Emma Morton, Sahil S Kanani, Natalie Dee, Rosemary Xinhe Hu, Erin E Michalak

J Particip Med 2025;17:e59806

Perceptions Toward an Attentional Bias Modification Mobile Game Among Individuals With Low Socioeconomic Status Who Smoke: Qualitative Study

Perceptions Toward an Attentional Bias Modification Mobile Game Among Individuals With Low Socioeconomic Status Who Smoke: Qualitative Study

Attentional bias modification (ABM) is a CBM intervention approach where individuals are trained to refocus their attention away from substance cues, thereby severing previously formed associations [2]. One approach involves a visual-probe task where both neutral and substance-related stimuli are presented on a screen followed by a probe (eg, a small dot) to redirect the user’s attention to the neutral stimuli [19].

Michael Wakeman, Lydia Tesfaye, Gunnar Baskin, Tim Gregory, Greg Gruse, Erin Leahy, Brandon Kendrick, Sherine El-Toukhy

JMIR Serious Games 2025;13:e59515

Evaluating the Use of a Note-Taking App by Japanese Resident Physicians: Nationwide Cross-Sectional Study

Evaluating the Use of a Note-Taking App by Japanese Resident Physicians: Nationwide Cross-Sectional Study

Note-taking during learning has long been a mainstay of educational practice and data over the last 60 years, demonstrating its contribution to improved learning and test scores [1,2]. In 1995, a study on effective note-taking among students reported that free note-taking by learners was a particularly effective process [3]. A 2002 report noted that the most effective way for medical students to perform well was to take written notes on materials prepared in advance by the teachers [4].

Taiju Miyagami, Yuji Nishizaki, Taro Shimizu, Yu Yamamoto, Kiyoshi Shikino, Koshi Kataoka, Masanori Nojima, Gautam A Deshpande, Toshio Naito, Yasuharu Tokuda

JMIR Form Res 2025;9:e55087

Mono-Professional Simulation-Based Obstetric Training in a Low-Resource Setting: Stepped-Wedge Cluster Randomized Trial

Mono-Professional Simulation-Based Obstetric Training in a Low-Resource Setting: Stepped-Wedge Cluster Randomized Trial

This study aimed to evaluate the effect of a train-the-trainer program designed to provide technology-enhanced, mono-professional, simulation-based obstetric training on patient outcomes in Uganda [10]. A stepped-wedge cluster randomized trial was conducted from October 2014 until March 2016 at the medium- to high-risk labor ward at Mulago National Referral Hospital in Uganda. This hospital also functions as the main teaching facility for Makerere University College of Medicine and Health Sciences.

Anne A C van Tetering, Ella L de Vries, Peter Ntuyo, E R van den Heuvel, Annemarie F Fransen, M Beatrijs van der Hout-van der Jagt, Imelda Namagembe, Josaphat Byamugisha, S Guid Oei

JMIR Med Educ 2025;11:e54911

Telenursing Health Education and Lifestyle Modification Among Patients With Diabetes in Bangladesh: Protocol for a Pilot Study With a Quasi-experimental Pre- and Postintervention Design

Telenursing Health Education and Lifestyle Modification Among Patients With Diabetes in Bangladesh: Protocol for a Pilot Study With a Quasi-experimental Pre- and Postintervention Design

A pilot study with a quasi-experimental pre- and postintervention design will be implemented. As we will try to explore the participants’ characteristics, we want to conduct a pilot study to see the feasibility of this project among these participants. We plan to conduct quasi-experimental pre- and postintervention design, as we found in this setting randomization; case-control is rather difficult.

Michiko Moriyama, K A T M Ehsanul Huq, Lucy Mondol, Akhi Roy Mita, Niru Shamsun Nahar

JMIR Res Protoc 2025;14:e71849

Investigating Social Network Peer Effects on HIV Care Engagement Using a Fuzzy-Like Matching Approach: Cross-Sectional Secondary Analysis of the N2 Cohort Study

Investigating Social Network Peer Effects on HIV Care Engagement Using a Fuzzy-Like Matching Approach: Cross-Sectional Secondary Analysis of the N2 Cohort Study

Sociocentric study designs collect information about a “complete” network among members of a population or cohort of interest, whereas egocentric studies focus on the network of contacts that immediately surround a focal individual (ego) and often collect information from subgroups sampled from a larger population [1,9].

Cho-Hee Shrader, Dustin T Duncan, Redd Driver, Juan G Arroyo-Flores, Makella S Coudray, Raymond Moody, Yen-Tyng Chen, Britt Skaathun, Lindsay Young, Natascha del Vecchio, Kayo Fujimoto, Justin R Knox, Mariano Kanamori, John A Schneider

JMIR Public Health Surveill 2025;11:e64497

Improving Recruitment Through Social Media and Web-Based Advertising to Evaluate the Genetic Risk and Long-Term Complications in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Community-Based Survey

Improving Recruitment Through Social Media and Web-Based Advertising to Evaluate the Genetic Risk and Long-Term Complications in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Community-Based Survey

Next, we launched a nationwide Google Ad campaign. Advertisement-derived interest surveys identified potential participants who were then contacted by phone. Interest surveys reported the mode of recruitment through a single-choice answer of “a website,” “Facebook,” “Instagram,” “Google,” “referral,” or “other.” More detailed responses for choices like “other” were obtained through free response options. Referrals are defined as participants referred to the study by family, friends, or a physician.

Elizabeth A Williams, Michelle D Martin-Pozo, Alexis H Yu, Krystyna Daniels, Madeline Marks, April O'Connor, Elizabeth J Phillips

J Med Internet Res 2025;27:e63712