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Approach to Design and Evaluate Digital Tools to Enhance Young Adult Participation in Clinical Trials: Co-Design and Controlled Intercept Study

Tim Mackey, Raphael E Cuomo, Qing Xu, Tiana J McMann, Zhuoran Li, Mingxiang Cai, Christine Wenzel, Joshua S Yang

J Med Internet Res 2025;27:e70852

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Motivation Theories and Constructs in Experimental Studies of Online Instruction: Systematic Review and Directed Content Analysis

Adam Gavarkovs, Erin Miller, Jaimie Coleman, Tharsiga Gunasegaran, Rashmi A Kusurkar, Kulamakan Kulasegaram, Melanie Anderson, Ryan Brydges

JMIR Med Educ 2025;11:e64179

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Artificial Intelligence-Driven Biological Age Prediction Model Using Comprehensive Health Checkup Data: Development and Validation Study

Chang-Uk Jeong, Jacob S Leiby, Dokyoon Kim, Eun Kyung Choe

JMIR Aging 2025;8:e64473

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Identifying Deprescribing Opportunities With Large Language Models in Older Adults: Retrospective Cohort Study

Vimig Socrates, Donald S Wright, Thomas Huang, Soraya Fereydooni, Christine Dien, Ling Chi, Jesse Albano, Brian Patterson, Naga Sasidhar Kanaparthy, Catherine X Wright, Andrew Loza, David Chartash, Mark Iscoe, Richard Andrew Taylor

JMIR Aging 2025;8:e69504

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Sociodemographic Differences in Logins and Engagement With the Electronic Health Coach Messaging Feature of a Mobile App to Support Opioid and Stimulant Use Recovery: Results From a 1-Month Observational Study

We compared estimates of uptake and engagement for distinct sociodemographic subgroups and the group of individuals who did and did not participate in the research component of the program using Wilcoxon rank-sum tests for continuous measures and Pearson chi-square tests for categorical measures.

Lindsey M Filiatreau, Hannah Szlyk, Alex T Ramsey, Erin Kasson, Xiao Li, Zhuoran Zhang, Patricia Cavazos-Rehg

JMIR Mhealth Uhealth 2025;13:e54753

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A Novel Just-in-Time Intervention for Promoting Safer Drinking Among College Students: App Testing Across 2 Independent Pre-Post Trials

Philip I Chow, Jessica Smith, Ravjot Saini, Christina Frederick, Connie Clark, Maxwell Ritterband, Jennifer P Halbert, Kathryn Cheney, Katharine E Daniel, Karen S Ingersoll

JMIR Hum Factors 2025;12:e69873

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Association of Social Media Recruitment and Depression Among Racially and Ethnically Diverse Metabolic and Bariatric Surgery Candidates: Prospective Cohort Study

To explore the associations between recruitment methods, social media or nonsocial media, and depression history (yes/no), we conducted Pearson χ2 tests. Crude odds ratios were calculated using univariable logistic regression models to assess the relationship between recruitment method and depression history.

Jackson M Francis, Sitapriya S Neti, Dhatri Polavarapu, Folefac Atem, Luyu Xie, Olivia Kapera, Matthew S Mathew, Elisa Marroquin, Carrie McAdams, Jeffrey Schellinger, Sophia Ngenge, Sachin Kukreja, Benjamin E Schneider, Jaime P Almandoz, Sarah E Messiah