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(F) Lower socially active dwell time in AD versus HCs, and an interaction between socially active dwell time and AD when predicting social functioning, were observed. AD: Alzheimer disease; HC: healthy control; SCC: subjective cognitive complaints; SZ: schizophrenia; S1: state 1; S2: state 2; zt: hidden state at time point, t.
Where we use “1-hot” encoding for the latent variable, such that ztn=1 if the latent variable at time t belongs to the class n, and 0 otherwise.
J Med Internet Res 2025;27:e64007
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From the extended-cosine models, we extracted measures of 24-hour robustness (pseudo-F statistic, indicating how well the observed data fits the 24-hour curve); activity onset time (up-mesor, the time which the modeled activity level passes the middle modeled rhythm height prior to the peak); and activity offset time (down-mesor or the time which the modeled activity level passes the middle modeled rhythm height prior to the nadir).
JMIR Aging 2025;8:e67294
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Unintended Prolonged Opioid Use: Protocol for a Case-Controlled Trial
JMIR Res Protoc 2025;14:e72032
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The study complied with the 1964 Helsinki Declaration and its later amendments and was approved by the Ethics Committee of the Lega F. D’Oro, Osimo (AN), Italy (P030820241).
Figures 2 reports the data for Liam, Hallie, Logan, and Kali and Figure 3 reports the data for Harper, Jacob, Millie, and Isabel over the different phases of the study. Each data point represents the mean frequency of responses per session over a block (group) of sessions.
JMIR Rehabil Assist Technol 2025;12:e70378
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