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Clinical Efficacy and Safety of the Herbal Prescription, HH333, in Preventing Recurrent Stroke in Patients With Ischemic Stroke Induced by Small-Vessel Disease: Protocol for Multicenter, Double-Blind, Randomized, Prospective, Pilot Clinical Trial

An estimated glomerular filtration rate < 60 m L/min/1.73 m2 at screening. Within 24 hours of onset. Patients with Korean National Institutes of Health Stroke Scale (K-NIHSS) score 21 to 42. Pregnant, nurses, or women of childbearing potential who have negative pregnancy test results and have not agreed to use contraception during the study.

Han-Gyul Lee, Seungwon Kwon, Woo-Sang Jung, Sang-Kwan Moon, Cheol-Hyun Kim, Dong-Jun Choi

JMIR Res Protoc 2025;14:e70953

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The Healing Through Ongoing Psychological Empowerment Telehealth Intervention With Two Spirit, Transgender, and Nonbinary Clients of Color in the United States: Open Clinical Trial Feasibility and Implementation Analysis

postinterview, 10 of 47 (21%) participants indicated that their most frequent criticism of the study was that clients did not like filling out the surveys prior to the sessions, for example, when Alex (all names provided for quotes are pseudonyms; 29 years, Black, trans nonbinary client) was asked about any changes they would make to study procedures, they said: “Not taking the surveys before (laughs) each session um that was a little difficult to do beforehand especially because the timing that [therapist’s name] and I

Stephanie Lynne Budge, Elliot Aaron Tebbe, Joonwoo Lee, Sergio Domínguez Jr, Em Matsuno, Louis Lindley

JMIR Form Res 2025;9:e64477

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Stigma Attitudes Toward HIV/AIDS From 2011 Through 2023 in Japan: Retrospective Study in Japan

“I don’t want to be with homosexuals because I don’t want to get AIDS.” “Black people have quite a lot of HIV infections.” Marks refer to potentially stigmatizing images, describing ways to identify members of a stigmatized group. To be most effective, marks may be visible physical features, perceived as disgusting, recognized quickly, and remembered. “I was chatting with an infectious disease doctor and the topic of AIDS came up.

Yi Piao, Nao Taguchi, Keisuke Harada, Kunihiro Hirahara, Yosuke Takaku, John Austin, KuanYeh Lee, Yui Shiozawa, Yunfei Cheng, Yoji Inoue

J Med Internet Res 2025;27:e69696

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Classifying the Information Needs of Survivors of Domestic Violence in Online Health Communities Using Large Language Models: Prediction Model Development and Evaluation Study

I have {24} samples of posts from domestic violence survivors seeking {Legal} this kind of information support from online. Now, I want to generate {100} more samples that mimic the style, content, keywords, emotion, and length of the existing data also seeking {Legal} this kind of information support. You should focus on the shared and frequent keywords in these samples.

Shaowei Guan, Vivian Hui, Gregor Stiglic, Rose Eva Constantino, Young Ji Lee, Arkers Kwan Ching Wong

J Med Internet Res 2025;27:e65397

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Telehealth Interventions in Pharmacy Practice: Systematic Review of Reviews and Recommendations

Rachel Lai Kay Chong, Andrew Siang Ee Chan, Crystal Min Siu Chua, Yi Feng Lai

J Med Internet Res 2025;27:e57129

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The Prevalence and Incidence of Suicidal Thoughts and Behavior in a Smartphone-Delivered Treatment Trial for Body Dysmorphic Disorder: Cohort Study

Answer choices included: 0 (“I do not think of suicide or death”), 1 (“I feel that life is empty or wonder if it’s worth living”), 2 (“I think of suicide or death several times a week for several minutes”), and 3 (“I think of suicide or death several times a day in some detail, or I have made specific plans for suicide or have actually tried to take my life”). An item from the CGI-BDD was used to determine whether participants perceived their past-week BDD symptoms improving or worsening.

Adam C Jaroszewski, Natasha Bailen, Simay I Ipek, Jennifer L Greenberg, Susanne S Hoeppner, Hilary Weingarden, Ivar Snorrason, Sabine Wilhelm