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Cognitive Behavioral Immersion for Depression: Protocol for a Three-Arm Randomized Controlled Trial of Peer-Based Coaching in the Metaverse

Cognitive Behavioral Immersion for Depression: Protocol for a Three-Arm Randomized Controlled Trial of Peer-Based Coaching in the Metaverse

Power analyses were focused on the ability to detect a medium effect size (Cohen d=0.50) at postcondition in the context of a 2-level random coefficients HLM. Given that the primary contrast of interest would be that between CBI and the other study conditions, calculations were focused on detecting significant differences between two active conditions. Where study parameters in this 2-level model were not yet known, we used standard values and varied parameters to approximate an effective sample size.

Noah Robinson, Francisco N Ramos, Steven D Hollon, Gloria T Han, Iony D Ezawa

JMIR Res Protoc 2025;14:e65970

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Virtual Versus In-Person Intensive Outpatient Treatment for Eating Disorders During the COVID-19 Pandemic in United States–Based Treatment Facilities: Naturalistic Study

Virtual Versus In-Person Intensive Outpatient Treatment for Eating Disorders During the COVID-19 Pandemic in United States–Based Treatment Facilities: Naturalistic Study

Cohen d effect sizes for all effects irrespective of statistical significance are reported and interpreted as small (d≥0.3), medium (d≥0.5), and large (d≥0.8) [33]. Odds ratios and 95% CIs are presented for logistic regression results.

Dan V Blalock, Philip S Mehler, Deborah M Michel, Alan Duffy, Daniel Le Grange, Anne M O'Melia, Renee D Rienecke

J Med Internet Res 2025;27:e66465

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