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The PMIS (Pearson r=−0.76; P
As we examined the sensitivity and specificity data to choose cut scores, we chose to favor sensitivity to minimize missing individuals with true disease in this sample of patients considered high risk because of their cognitive concerns. The cut scores for a positive result on the 5-Cog components were as follows: PMIS ≤6 (range 0-8), Symbol Match ≤25 (range 0-65), and s MCR >5 (range 0-7).
JMIR Res Protoc 2025;14:e60471
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The study team will use standard statistical packages (eg, R [R Foundation for Statistical Computing]) to conduct data analysis. Descriptive statistics (means, SD, frequency distributions, and proportions) will be used to summarize baseline patient characteristics, clinical and behavioral outcomes, and other quantitative outcome measures and responses to closed-ended survey items.
JMIR Res Protoc 2025;14:e62916
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The application of this mapping to the data was performed using R version 4.3.2 (R Foundation for Statistical Computing). The full list of diagnosis names corresponding to ADRD diagnosis categories is provided in Multimedia Appendix 1.
To assess associations between clusters and sex, as well as ADRD diagnoses, we used the chi-square test.
JMIR Aging 2025;8:e65178
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We hypothesized moderate correlations (r>0.30 and
Known-groups validity in a longitudinal context is examined by the assessment of average change in subgroups that are expected to have experienced a different amount of change in function after surgery.
JMIR Form Res 2025;9:e69001
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