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Examining Weight Suppression, Leptin Levels, Glucagon-Like Peptide 1 Response, and Reward-Related Constructs in Severity and Maintenance of Bulimic Syndromes: Protocol and Sample Characteristics for a Cross-Sectional and Longitudinal Study

Examining Weight Suppression, Leptin Levels, Glucagon-Like Peptide 1 Response, and Reward-Related Constructs in Severity and Maintenance of Bulimic Syndromes: Protocol and Sample Characteristics for a Cross-Sectional and Longitudinal Study

We observed stability in BMI across days (r>0.95; P The Eating Disorder Examination (EDE) 17.0 D [83] was selected due to previous evidence of good discriminant validity [84-87], IRR (0.83 to 0.99) [88,89], and good internal consistency of the restraint and body image subscales (Cronbach α>0.70) [90].

Pamela K Keel, Lindsay P Bodell, Sarrah I Ali, Austin Starkey, Jenna Trotta, J Woody Luxama, Chloé Halfhide, Naomi G Hill, Jonathan Appelbaum, Diana L Williams

JMIR Res Protoc 2025;14:e66554

Digital Health Intervention to Reduce Malnutrition Among Individuals With Gastrointestinal Cancer Receiving Cytoreductive Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy: Feasibility, Acceptability, and Usability Trial

Digital Health Intervention to Reduce Malnutrition Among Individuals With Gastrointestinal Cancer Receiving Cytoreductive Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy: Feasibility, Acceptability, and Usability Trial

Compared to baseline, average PG-SGA malnutrition scores saw a decrease of 6 points (P=.01), with a corresponding reduction in patients with high malnutrition risk (P=.03; Table 4). Functional Assessment of Cancer Therapy—General scores increased by an average of 20.5 points (P=.002), and Functional Assessment of Anorexia/Cachexia Treatment—Anorexia/Cachexia Scale scores increased by an average of 7.4 points (P=.03), indicating an improvement in participants’ health-related quality of life.

Yu Chen Lin, Ryan Hagen, Benjamin D Powers, Sean P Dineen, Jeanine Milano, Emma Hume, Olivia Sprow, Sophia Diaz-Carraway, Jennifer B Permuth, Jeremiah Deneve, Amir Alishahi Tabriz, Kea Turner

JMIR Cancer 2025;11:e67108

Using Large Language Models to Automate Data Extraction From Surgical Pathology Reports: Retrospective Cohort Study

Using Large Language Models to Automate Data Extraction From Surgical Pathology Reports: Retrospective Cohort Study

The LLM was significantly less accurate than both reviewer 1 (P Twelve medical questions and sample large language model (LLM) answers with the rates of concordance between the reviewers and the LLM. a R1: Reviewer 1. b R2: Reviewer 2. c TNM: Tumor-Node-Metastasis. We demonstrated and evaluated the extraction performance of a locally deployed, open-source LLM for a specific clinical NLP task.

Denise Lee, Akhil Vaid, Kartikeya M Menon, Robert Freeman, David S Matteson, Michael L Marin, Girish N Nadkarni

JMIR Form Res 2025;9:e64544

Urologists’ Estimation of Online Support Group Utilization Behavior of Their Patients With Newly Diagnosed Nonmetastatic Prostate Cancer in Germany: Predefined Secondary Analysis of a Randomized Controlled Trial

Urologists’ Estimation of Online Support Group Utilization Behavior of Their Patients With Newly Diagnosed Nonmetastatic Prostate Cancer in Germany: Predefined Secondary Analysis of a Randomized Controlled Trial

Thus, no patient in the COVID-19 group attended an F2 FG (7/308, 2.3% vs 0/379, 0%, respectively; P=.003). Most patients (471/687, 68.6%) reported having no interest in F2 FGs. Another 122 (17.8%) of the 687 patients did not know about F2 FGs, and 66 (9.6%) had other reasons for not attending. OSGs were used by 165 (24%) patients. The frequency of OSG use did not change significantly before (76/308, 24.7%) or during (89/379, 23.5%) the COVID-19 pandemic (P=.72).

Philipp Karschuck, Christer Groeben, Rainer Koch, Tanja Krones, Andreas Neisius, Sven von Ahn, Christian Peter Klopf, Steffen Weikert, Michael Siebels, Nicolas Haseke, Christian Weissflog, Martin Baunacke, Christian Thomas, Peter Liske, Georgi Tosev, Thomas Benusch, Martin Schostak, Joachim Stein, Philipp Spiegelhalder, Andreas Ihrig, Johannes Huber

J Med Internet Res 2025;27:e56092