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Combining Artificial Intelligence and Human Support in Mental Health: Digital Intervention With Comparable Effectiveness to Human-Delivered Care

Combining Artificial Intelligence and Human Support in Mental Health: Digital Intervention With Comparable Effectiveness to Human-Delivered Care

A significant P value ( The study was preregistered (ISRCTN ID: 52546704) and obtained ethical approval before recruitment (IRAS ID: 327897, NHS Research Ethics Committee: West of Scotland REC 4). In line with the Declaration of Helsinki, all prospective participants provided signed informed consent and were debriefed following the study. This study was conducted in accordance with Good Clinical Practice (GCP) principles.

Clare E Palmer, Emily Marshall, Edward Millgate, Graham Warren, Michael Ewbank, Elisa Cooper, Samantha Lawes, Alastair Smith, Chris Hutchins-Joss, Jessica Young, Malika Bouazzaoui, Morad Margoum, Sandra Healey, Louise Marshall, Shaun Mehew, Ronan Cummins, Valentin Tablan, Ana Catarino, Andrew E Welchman, Andrew D Blackwell

J Med Internet Res 2025;27:e69351