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Notably, NMUPO is strongly linked with the initiation of heroin and synthetic opioid use (eg, fentanyl) in young adults, posing a substantial risk for the development of substance use disorder (SUD) and overdose [13]. Hence, interventions targeting young adults are urgently needed to address NMUPO, and those should be delivered beyond the college population [14].
Interventions for NMUPO in young adults should take psychosocial factors into account.
JMIR Res Protoc 2025;14:e65847
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Our findings align with previous research indicating the effectiveness of digital interventions in reducing alcohol consumption, particularly among the young male population [52], which mirrors the demographic of our study. Other studies have also shown positive effects in the general population, suggesting that such interventions could have broad applicability [29,31,53-55].
JMIR Form Res 2025;9:e64459
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