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Large Language Models in Biochemistry Education: Comparative Evaluation of Performance

Large Language Models in Biochemistry Education: Comparative Evaluation of Performance

The item analysis suggested that Claude correctly answered all questions (100%) from the following 12 categories: structure and function of proteins, bioenergetics and electron transport chain, enzymes, signaling mechanisms, pyruvate dehydrogenase and Krebs cycle, cholesterol metabolism, eicosanoids, fructose and galactose metabolism, hexose monophosphate pathway, ketone bodies, heme metabolism, and nitrogen metabolism. The lowest result (81.8%) was recorded for the lipoproteins.

Olena Bolgova, Inna Shypilova, Volodymyr Mavrych

JMIR Med Educ 2025;11:e67244