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Development of the InCharge Health Mobile App to Improve Adherence to Hydroxyurea in Patients With Sickle Cell Disease: User-Centered Design Approach

Development of the InCharge Health Mobile App to Improve Adherence to Hydroxyurea in Patients With Sickle Cell Disease: User-Centered Design Approach

Hydroxyurea (also known as hydroxycarbamide) is a medication approved by the US Food and Drug Administration (FDA) that has several health benefits and is cost-effective in pediatric and adult patients with SCD [7-19]. Hydroxyurea induces fetal hemoglobin production, thereby decreasing sickle hemoglobin erythrocyte polymers, hemolysis, and vaso-occlusion [10,11].

Nicole M Mohamed Alberts, Sherif M Badawy, Jason Hodges, Jeremie H Estepp, Chinonyelum Nwosu, Hamda Khan, Matthew P Smeltzer, Ramin Homayouni, Sarah Norell, Lisa Klesges, Jerlym S Porter, Jane S Hankins

JMIR Mhealth Uhealth 2020;8(5):e14884