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Reference 4: Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised Reference 35: Hydroxycarbamide adherence and cumulative dose associated with hospital readmission inhydroxycarbamide
JMIR Res Protoc 2020;9(7):e16319
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Hydroxyurea (also known as hydroxycarbamide) is a medication approved by the US Food and Drug Administration (FDA) that has several health benefits and is cost-effective in pediatric and adult patients with SCD [7-19]. Hydroxyurea induces fetal hemoglobin production, thereby decreasing sickle hemoglobin erythrocyte polymers, hemolysis, and vaso-occlusion [10,11].
JMIR Mhealth Uhealth 2020;8(5):e14884
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