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Published on in Vol 14 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/68394, first published .
Mobile app interface for mental wellness with sections for mood tracking, knowledge, and relaxation.

Long-Term Effectiveness of Unguided Internet-Based Cognitive Behavioral Therapy on Major Depressive Disorder in Chinese Adults: Randomized Controlled Trial With a 12-Month Follow-Up

Long-Term Effectiveness of Unguided Internet-Based Cognitive Behavioral Therapy on Major Depressive Disorder in Chinese Adults: Randomized Controlled Trial With a 12-Month Follow-Up

Wenjing Zhou   1, 2 * , PhD ;   Huimin Zhang   3 * , PhD ;   Yunbin Jiang   1, 2 , MPH ;   Yanzhi Li   1, 2 , PhD ;   Guangduoji Shi   1, 2 , PhD ;   Hao Zhao   1, 2 , PhD ;   Wanxin Wang   1, 2 , PhD ;   Yuhua Liao   3 , PhD ;   Yifeng Liu   3 , MS ;   Jiejing Hao   1, 2, 3 , PhD ;   Roger S McIntyre   4 , MD ;   Beifang Fan   3 , MM ;   Ciyong Lu   1 , PhD

1 Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China

2 Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, Guangzhou, China

3 Department of Psychiatry, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China

4 Department of Psychiatry, University of Toronto, Toronto, ON, Canada

*these authors contributed equally

Corresponding Author:

  • Ciyong Lu, PhD
  • Department of Medical Statistics and Epidemiology
  • School of Public Health, Sun Yat-sen University
  • 74 Zhongshan 2nd
  • Guangzhou 510080
  • China
  • Phone: 86 13610355985
  • Email: luciyong@mail.sysu.edu.cn