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The Role of Machine Learning in Cognitive Impairment in Parkinson Disease: Systematic Review and Meta-Analysis

The Role of Machine Learning in Cognitive Impairment in Parkinson Disease: Systematic Review and Meta-Analysis

Chen et al [32] combined SVM with principal component analysis to successfully extract 6 features from 32 predictors, improving the performance over the simple SVM model. Other models use unsupervised learning to cluster this unlabeled data and then use supervised learning for longitudinal prediction [33]. Further research and discussion are needed to assess the accuracy and effectiveness of these different models. We found that cognitive tests such as the MMSE and the Mo CA were mostly used as predictors.

Yanyun Wu, Yangfan Cheng, Yi Xiao, Huifang Shang, Ruwei Ou

J Med Internet Res 2025;27:e59649