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(D) IUH: negative 5-Cog result.
At both sites, a paper token (Figure 4) is used as an additional feature to help ensure that care providers review the patients’ 5-Cog results. Patients are handed this token after they complete the 5-Cog battery and are asked to hand it to their care provider at their scheduled visit, generally within 30 minutes after the 5-Cog battery administration.
Token to alert care provider for patient's 5-Cog participation.
JMIR Res Protoc 2025;14:e60471
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Indeed, a meta-analysis of VR-assisted exposure therapy for anxiety disorders showed a large overall effect size for VR exposure therapy compared with (mostly waitlist) control conditions (Cohen d=1.11, SE 0.15, 95% CI 0.82-1.39) [28]. Furthermore, research on the use of VR for psychosis treatment has indicated the approach can be feasible, acceptable, and effective for improving some symptoms including positive symptoms such as paranoia and hallucinations [29].
JMIR Res Protoc 2025;14:e63405
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Among vapers, almost three-fourth (n=3750, 74.6%) were current vapers (vaped within the past 30 d), more than 40% were current smokers (n=2055, 40.9% smoked at least one cigarette in the past 30 d), and more than 48% were current poly-users (using e-cigarettes and one or more other tobacco products). In addition, substantial numbers of current vapers also currently use some other product, including cigars (n=1520, 30.2%), hookah (n=794, 15.8%), smokeless devices (n=462, 9.2%), and ONPs (n=578, 11.5%).
J Med Internet Res 2025;27:e72002
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The group with impairment (a) is disaggregated into the subgrouped types of impairment from Figure 2 (b-d). The numeric values visualized in this figure are presented in Tables S1 and S3-S5 in Multimedia Appendix 2.
JMIR Public Health Surveill 2025;11:e64707
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Each observation was represented by the triplet {X,T,S}, where X⊆Rd is a d-dimensional feature vector, T∈(0,Emax] is an observed event or censoring time over a finite time horizon, and S∈{0,1} indicates whether T is a right-censoring time (S=0) or an event time (S=1). The observed time T is the minimum of the event time E and the right-censoring time C, that is, T=min(E, C).
JMIR AI 2025;4:e62985
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In terms of the aim for the preliminary efficacy evaluation (ie, secondary outcomes of psychosocial and behavioral factors associated with NMUPO), we estimate an effect size according to a previous review on digital interventions for illicit drug use [111] and found small-to-medium effect sizes (Cohen d=–0.17 to –0.34) with a 6-month follow-up assessment. G-power analysis [112] estimated a sample size of 10 to 35 per arm for an RCT (repeated measures analysis of covariance).
JMIR Res Protoc 2025;14:e65847
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