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Feasibility of a Progesterone-Modified Natural Protocol for Frozen Embryo Transfer: Protocol for a Pilot Cohort Study

Feasibility of a Progesterone-Modified Natural Protocol for Frozen Embryo Transfer: Protocol for a Pilot Cohort Study

Overall, this study aims to provide greater flexibility in timing transfer by providing participants with vaginal pessaries of P4 to be used before FET and, subsequently, confirming the absence of elevated endogenous P4 on the day of P4 supplementation start and confirming the presence of a corpus luteum on an ultrasound scan.

Alexandra Churchill, Ektoras Georgiou, Veronica Abruzzo, Alex Polyakov, Wan Tinn Teh

JMIR Res Protoc 2025;14:e66579

Efficacy of a Digital Postoperative Rehabilitation Intervention in Patients With Primary Liver Cancer: Randomized Controlled Trial

Efficacy of a Digital Postoperative Rehabilitation Intervention in Patients With Primary Liver Cancer: Randomized Controlled Trial

Digital health is an important medium for the delivery of rehabilitation interventions based on mobile devices, providing health education to improve the awareness of liver cancer rehabilitation, assisting in self-management and improving compliance with liver cancer rehabilitation, real-time exercise monitoring to improve the safety of discharged liver cancer rehabilitation, which could serve as a viable and accessible support platform.

Kaitao Yu, Baobing Yin, Ying Zhu, Hongdao Meng, Wenwei Zhu, Lu Lu, Junqiao Wang, Shugeng Chen, Jun Ni, Yifang Lin, Jie Jia

JMIR Mhealth Uhealth 2025;13:e59228

Wearable Activity Tracker–Based Interventions for Physical Activity, Body Composition, and Physical Function Among Community-Dwelling Older Adults: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Wearable Activity Tracker–Based Interventions for Physical Activity, Body Composition, and Physical Function Among Community-Dwelling Older Adults: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Unlike those in institutional settings, community-dwelling older adults have greater opportunities to integrate interventions into their daily routines, making them an important target for interventions aimed at promoting healthy aging. In addition, variations in follow-up periods and control group types across studies complicate the interpretation of results, as these factors can influence observed outcomes [30-34].

Ran Li, Yangan Li, Lu Wang, Lijuan Li, Chenying Fu, Danrong Hu, Quan Wei

J Med Internet Res 2025;27:e59507

Effect of a WeChat-Based Hybrid Intervention on the Adaptation Outcomes of People Living With HIV/AIDS: Pilot Randomized Controlled Trial

Effect of a WeChat-Based Hybrid Intervention on the Adaptation Outcomes of People Living With HIV/AIDS: Pilot Randomized Controlled Trial

Mobile health (m Health) provides an optimal foundation for delivering care to people living with HIV/AIDS at a lower cost compared to purely offline interventions [25-27]. However, an extensive synthesis of systematic reviews has highlighted a notable gap in the literature [28,29]: the majority of existing intervention studies have not specifically aimed to address Qo L and have shown the equivocal nature of the effect of interventions on Qo L.

Honghong Wang, Ziqi Qin, Yixuan Li, Yuqiong Duan, Qiaoyue Lu, Xueling Xiao

J Med Internet Res 2025;27:e65268

Authors’ Reply: Balancing Challenges and Opportunities When Evaluating Remote Rehabilitation for Sarcopenia in Older Adults

Authors’ Reply: Balancing Challenges and Opportunities When Evaluating Remote Rehabilitation for Sarcopenia in Older Adults

Therefore, before formally using the app for training, the telerehabilitation group attended an in-person session, where a physical therapist guided the participants through a simulation of the movements and provided detailed instructions on how to use the app. This was done to ensure that participants could follow our intended exercise protocols as closely as possible during home-based training and to minimize individual differences in understanding.

Lu Zhang, Ying Ge, Wowa Zhao, Xuan Shu, Lin Kang, Qiumei Wang, Ying Liu

J Med Internet Res 2025;27:e73174

Ability of ChatGPT to Replace Doctors in Patient Education: Cross-Sectional Comparative Analysis of Inflammatory Bowel Disease

Ability of ChatGPT to Replace Doctors in Patient Education: Cross-Sectional Comparative Analysis of Inflammatory Bowel Disease

Including Crohn disease and ulcerative colitis, IBD is an increasingly prevalent chronic intestinal disease in China, characterized by primary invasion of the digestive system and cumulative multisystem involvement of autoimmune diseases, with no cure currently available. Patients have a strong need to learn and reinforce self-care abilities, among which the We Chat public account of the China Crohn’s and Colitis Foundation (CCCF) is the most popular with IBD patients [19].

Zelin Yan, Jingwen Liu, Yihong Fan, Shiyuan Lu, Dingting Xu, Yun Yang, Honggang Wang, Jie Mao, Hou-Chiang Tseng, Tao-Hsing Chang, Yan Chen

J Med Internet Res 2025;27:e62857

Correction: Auricular Acupressure Versus an Intermittent Low-Carbohydrate Diet in Children With Overweight or Obesity With Gastric-Heat and Dampness-Obstruction Syndrome: Protocol for a Randomized Controlled Trial

Correction: Auricular Acupressure Versus an Intermittent Low-Carbohydrate Diet in Children With Overweight or Obesity With Gastric-Heat and Dampness-Obstruction Syndrome: Protocol for a Randomized Controlled Trial

In “Auricular Acupressure Versus an Intermittent Low-Carbohydrate Diet in Children With Overweight or Obesity With Gastric-Heat and Dampness-Obstruction Syndrome: Protocol for a Randomized Controlled Trial” the authors noted 3 changes.

Wen Sun, Jingwei He, Wenqin Wang, Chen Lu, Yating Lin, Yalan Dou, Weili Yan, Jian Yu

JMIR Res Protoc 2025;14:e74014

Efficacy of a Web-Based Integrated Growth Mindset Intervention on Reducing Anxiety Among Social Work and Counseling Practicum Trainees: Protocol for a 2-Arm Randomized Controlled Trial

Efficacy of a Web-Based Integrated Growth Mindset Intervention on Reducing Anxiety Among Social Work and Counseling Practicum Trainees: Protocol for a 2-Arm Randomized Controlled Trial

Practicum is an essential educational component of professional training [1,2], bridging the gap between theory and practice and enhancing the professional capacity and core competence of future practitioners [3,4]. The quality of fieldwork profoundly influences social work trainees’ personal, intellectual, and professional development [4], per communication skills, critical reflection, professional growth, creativity, innovation, and self-efficacy [1,5].

Yongyi Wang, An Xi, Stella S K Wong, Kong Yam, Janet Tsin Yee Leung, Shimin Zhu

JMIR Res Protoc 2025;14:e67234