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Prehabilitation Program for Lung and Esophageal Cancers (Boosting Recovery and Activity Through Early Wellness): Protocol for a Nonrandomized Trial

Prehabilitation Program for Lung and Esophageal Cancers (Boosting Recovery and Activity Through Early Wellness): Protocol for a Nonrandomized Trial

The thoracic surgeon will then raise the subject of prehabilitation with patients. At this point, patients will have the choice to participate in the prehabilitation program or not. If the participants do not agree to the study, they will continue with a standard of care.

Jodi E Langley, Daniel Sibley, Joy Chiekwe, Melanie R Keats, Stephanie Snow, Judith Purcell, Stephen Sollows, Leslie Hill, David Watton, Abbigael E Gaudry, Ibrahim Hashish, Alison Wallace

JMIR Res Protoc 2025;14:e60791

Feasibility of a Comprehensive eCoach to Support Patients Undergoing Colorectal Surgery: Longitudinal Observational Study

Feasibility of a Comprehensive eCoach to Support Patients Undergoing Colorectal Surgery: Longitudinal Observational Study

Many health apps for perioperative guidance are available, but the content is often narrow and applied to only one aspect of the care pathway, such as prehabilitation or postoperative monitoring [11-14]. An e Coach for colorectal surgery was reported, but did not include prehabilitation, for which digital coaching can be particularly helpful [15]. Furthermore, clear reporting of feasibility for older surgical patients in real-life clinical practice is often missing [16,17].

A Daniëlle Talen, Jobbe P L Leenen, Geert van der Sluis, Hilbrand K E Oldenhuis, Joost M Klaase, Gijsbert A Patijn

JMIR Perioper Med 2025;8:e67425

Validity, Accuracy, and Safety Assessment of an Aerobic Interval Training Using an App-Based Prehabilitation Program (PROTEGO MAXIMA Trial) Before Major Surgery: Prospective, Interventional Pilot Study

Validity, Accuracy, and Safety Assessment of an Aerobic Interval Training Using an App-Based Prehabilitation Program (PROTEGO MAXIMA Trial) Before Major Surgery: Prospective, Interventional Pilot Study

The Prehab App has been developed as a platform linked to a wearable device, enabling individualized, risk-adjusted, home-based aerobic exercise training as prehabilitation before major surgery. The objective of the prospective interventional PROTEGO MAXIMA trial was to evaluate the accuracy of wearable measurements and the safety of the prehabilitation program compared with certified electrocardiogram (ECG) measurements in a supervised and controlled environment.

Sara Fatima Faqar Uz Zaman, Svenja Sliwinski, Lisa Mohr-Wetzel, Julia Dreilich, Natalie Filmann, Charlotte Detemble, Dora Zmuc, Felix Chun, Wojciech Derwich, Waldemar Schreiner, Wolf Bechstein, Johannes Fleckenstein, Andreas A Schnitzbauer

JMIR Mhealth Uhealth 2025;13:e55298

Feasibility, User Acceptance, and Outcomes of Using a Cancer Prehabilitation App for Exercise: Pilot Cohort Study

Feasibility, User Acceptance, and Outcomes of Using a Cancer Prehabilitation App for Exercise: Pilot Cohort Study

Prehabilitation also involves the identification of potential impairments and the implementation of targeted interventions aimed at optimizing health, thereby reducing the risk and severity of future treatment-related complications. The efficacy of cancer prehabilitation programs is supported by findings from several international reviews and meta-analyses [2-4].

Fuquan Zhang, Deepali Bang, Christine Alejandro Visperas, Mon Hnin Tun, San San Tay

JMIR Form Res 2025;9:e64427

Effects of Prehabilitation With Advanced Technologies in Patients With Musculoskeletal Diseases Waiting for Surgery: Systematic Review and Meta-Analysis

Effects of Prehabilitation With Advanced Technologies in Patients With Musculoskeletal Diseases Waiting for Surgery: Systematic Review and Meta-Analysis

The term “prehabilitation” refers to actively preparing patients for surgery through interventions such as exercise, nutritional support, psycho-cognitive training, or a combination thereof, to enhance functional capacity and improve tolerance to upcoming surgical stress [3,5]. Although prehabilitation is highly valued by patients, the evidence supporting its benefits in the musculoskeletal field is varied and uncertain [3,8].

Stefania Guida, Jacopo Antonino Vitale, Eva Swinnen, David Beckwée, Silvia Bargeri, Federico Pennestrì, Greta Castellini, Silvia Gianola

J Med Internet Res 2024;26:e52943

Usability Testing of a Digitized Interventional Prehabilitation Tool for Health Care Professionals and Patients Before Major Surgeries: Formative and Summative Evaluation

Usability Testing of a Digitized Interventional Prehabilitation Tool for Health Care Professionals and Patients Before Major Surgeries: Formative and Summative Evaluation

Prehabilitation is a new field in clinical medicine that focuses on the optimal preparation of a patient for an operation [1]. The concept is based on multiple pillars of short-term lifestyle modifications predominantly reflecting the World Health Organization’s (WHO) recommendations for physical activity and the European code against cancer [2,3]. Specifically, it focuses on physical activity, mental well-being, and optimal nutrition.

Andreas A Schnitzbauer, Charlotte Detemble, Sara Fatima Faqar-Uz-Zaman, Julia Dreilich, Lisa Mohr, Svenja Sliwinski, Dora Zmuc, Mark Siller, Johannes Fleckenstein

JMIR Form Res 2024;8:e59513

Health Behavior Change Intervention Preferences Expressed by American Indian Cancer Survivors From a Southwest Tribal Community: Semistructured Interview Study

Health Behavior Change Intervention Preferences Expressed by American Indian Cancer Survivors From a Southwest Tribal Community: Semistructured Interview Study

Lifestyle modifications in nutrition and exercise prior to oncologic treatment are key strategies of prehabilitation (prehab) and have been shown to optimize patients’ functional capacity and improve postoperative outcomes [24-26]. Results from this work are being used to propose the next evolution of this project, which is the adaptation of a culturally appropriate prehab program for San Carlos Apache patients diagnosed with cancer who are preparing for surgery.

Jennifer Erdrich, Felina M Cordova-Marks, William O Carson, Jennifer W Bea, William R Montfort, Cynthia A Thomson

JMIR Form Res 2024;8:e51669

Supporting Life Adjustment in Patients With Lung Cancer Through a Comprehensive Care Program: Protocol for a Controlled Before-and-After Trial

Supporting Life Adjustment in Patients With Lung Cancer Through a Comprehensive Care Program: Protocol for a Controlled Before-and-After Trial

In conclusion, the LC3 P represents a proactive, holistic prehabilitation intervention aimed at supporting lung cancer survivors, as they navigate the transition to life after treatment. Our findings highlight the impact of early informational support on patients’ psychological adaptation and postdiagnosis stress management. This could potentially establish a new standard for the timing and delivery of survivorship care, emphasizing the benefits of early intervention.

Wonyoung Jung, Alice Ahn, Genehee Lee, Sunga Kong, Danbee Kang, Dongok Lee, Tae Eun Kim, Young Mog Shim, Hong Kwan Kim, Jongho Cho, Juhee Cho, Dong Wook Shin

JMIR Res Protoc 2024;13:e54707

Prehabilitation in an Integrative Medicine Day Clinic for Patients Undergoing Neoadjuvant Treatment: Single-Center Feasibility Pilot Study

Prehabilitation in an Integrative Medicine Day Clinic for Patients Undergoing Neoadjuvant Treatment: Single-Center Feasibility Pilot Study

Analysis of these concepts of “prehabilitation” indicated efficacy [2,3]. The initial results were positive even in rather short (2-4 weeks) interventions comprising several sessions. However, there is growing evidence that these early prehabilitation concepts lacked fundamental aspects of preparation [4]. First, they did not address anxiety, patients’ empowerment, or strengthening of self-efficacy, which is well known to have a beneficial effect on cancer care [5].

Christian Raff, Colette Dörr-Harim, Stephanie Otto, Johanna Thiele, Andre Mihaljevic, Klaus Kramer

JMIR Res Protoc 2023;12:e46765