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Peer Review of “Health Care System Overstretch and In-Hospital Mortality of Intubated Patients With COVID-19 in Greece From September 2020 to April 2022: Updated Retrospective Cohort Study”

Peer Review of “Health Care System Overstretch and In-Hospital Mortality of Intubated Patients With COVID-19 in Greece From September 2020 to April 2022: Updated Retrospective Cohort Study”

Variation in the COVID-19 infection–fatality ratio by age, time, and geography during the pre-vaccine era: a systematic analysis. Lancet. Apr 16, 2022;399(10334):1469-1488. Benati I, Coccia M. Effective contact tracing system minimizes COVID-19 related infections and deaths: policy lessons to reduce the impact of future pandemic diseases. J Pub Admin Gov. Sept 2022;12(3):19-33. Velissaris D, Paraskevas T, Oikonomou E, Bizos A, Karamouzos V, Marangos M.

Mario Coccia

JMIRx Med 2024;5:e59638

Author’s Response to Peer Reviews of “Health Care System Overstretch and In-Hospital Mortality of Intubated Patients With COVID-19 in Greece From September 2020 to April 2022: Updated Retrospective Cohort Study”

Author’s Response to Peer Reviews of “Health Care System Overstretch and In-Hospital Mortality of Intubated Patients With COVID-19 in Greece From September 2020 to April 2022: Updated Retrospective Cohort Study”

Response: Examining the time lag between vaccination and disease onset was not part of our analysis; 11,944 of 14,011 patients (85.2%) were unvaccinated, as is already reported on Table 1; we have now included this information in the text and in the abstract. “Vaccination did not show a statistically significant association with mortality, regardless of the number of doses received (Figure 2).” This needs rephrasing if all participants were vaccinated at least once. Response: No, they were not.

Theodore Lytras

JMIRx Med 2024;5:e59637

Health Care System Overstretch and In-Hospital Mortality of Intubated Patients With COVID-19 in Greece From September 2020 to April 2022: Updated Retrospective Cohort Study

Health Care System Overstretch and In-Hospital Mortality of Intubated Patients With COVID-19 in Greece From September 2020 to April 2022: Updated Retrospective Cohort Study

Follow-up time between intubation and extubation or death was split finely into days, and Poisson regression was used to estimate the hazard of dying as a function of fixed and time-varying covariates [4]. Deaths occurring up to 5 days after extubation were classified as deaths at the end of follow-up.

Theodore Lytras

JMIRx Med 2024;5:e43341

Durability of the Effectiveness of Heterologous COVID-19 Vaccine Regimens in Thailand: Retrospective Cohort Study Using National Registration Data

Durability of the Effectiveness of Heterologous COVID-19 Vaccine Regimens in Thailand: Retrospective Cohort Study Using National Registration Data

The time frame of this study was from May 2021 (when the COVID-19 vaccination started in Thailand) to July 2022 (when the compulsory registration of all COVID-19 cases ended). We assumed that all individuals residing in the same province would have a similar risk of exposure to SARS-Co V-2 during the pandemic. Figure 1 A displays the time series of notified SARS-Co V-2 infection, severe COVID-19, and deaths following hospitalization with COVID-19, while Figure 1 B shows the circulating variants.

Ponlagrit Kumwichar, Chittawan Poonsiri, Siobhan Botwright, Natchalaikorn Sirichumroonwit, Bootsakorn Loharjun, Supharerk Thawillarp, Nontawit Cheewaruangroj, Amorn Chokchaisiripakdee, Yot Teerawattananon, Virasakdi Chongsuvivatwong

JMIR Public Health Surveill 2024;10:e48255

The Relationship Between Lockdowns and Video Game Playtime: Multilevel Time-Series Analysis Using Massive-Scale Data Telemetry

The Relationship Between Lockdowns and Video Game Playtime: Multilevel Time-Series Analysis Using Massive-Scale Data Telemetry

Candidate effects are diverse and include the potential impact of containment and closure policies on screen time, education, alcohol consumption, diurnal rhythms, eating habits, and physical activity [11-16]. One particularly widely discussed potential effect concerns video gaming. The primary issue concerns the amount of time that individuals spend playing video games.

David Zendle, Catherine Flick, Darel Halgarth, Nick Ballou, Joe Cutting, Anders Drachen

J Med Internet Res 2023;25:e40190

Incorporating Consumers’ Needs in Nutrition Apps to Promote and Maintain Use: Mixed Methods Study

Incorporating Consumers’ Needs in Nutrition Apps to Promote and Maintain Use: Mixed Methods Study

Upon completion of the study, the participants received an incentive of €50 (conversion rate at the time of the study: €1=US $1.12) for their time investment. As a first step, the minutes and recordings of the discussions were analyzed by creating a descriptive matrix per question to identify common themes. Through this matrix, the reasons for discontinuation were identified. The model shown in Figure 1 was built using a bottom-up approach.

Sandra van der Haar, Ireen Raaijmakers, Muriel C D Verain, Saskia Meijboom

JMIR Mhealth Uhealth 2023;11:e39515

An Ensemble Learning Approach to Improving Prediction of Case Duration for Spine Surgery: Algorithm Development and Validation

An Ensemble Learning Approach to Improving Prediction of Case Duration for Spine Surgery: Algorithm Development and Validation

Martin and colleagues [2] reported the incidence of elective fusion of the lumbar spine increasing over 60% from 2004 to 2015, with hospital costs for such surgeries surging over 170% in the same time to an average of over US $50,000 per admission.

Rodney Allanigue Gabriel, Bhavya Harjai, Sierra Simpson, Austin Liu Du, Jeffrey Logan Tully, Olivier George, Ruth Waterman

JMIR Perioper Med 2023;6:e39650

Interrater Agreement on National Institutes of Health Stroke Scale Between Paramedics and Stroke Physicians: Validation Study for the Digital Training Model in the Paramedic Norwegian Acute Stroke Prehospital Project

Interrater Agreement on National Institutes of Health Stroke Scale Between Paramedics and Stroke Physicians: Validation Study for the Digital Training Model in the Paramedic Norwegian Acute Stroke Prehospital Project

The time spent on NIHSS registration was recorded by start time (new registration) and end time (data submitted) and directly transferred to the database. The stroke physicians scored according to their daily practice on the original NIHSS paper form, independently from each other and the paramedics. The stroke physicians were responsible for documenting their own time stamps for each video. The time spent on scoring the NIHSS for each video was reported in whole minutes.

Mona Guterud, Helge Fagerheim Bugge, Jo Røislien, Karianne Larsen, Erik Eriksen, Svein Håkon Ingebretsen, Martin Lerstang Mikkelsen, Jo Kramer-Johansen, Kristi G Bache, Else Charlotte Sandset, Maren Ranhoff Hov

JMIR Neurotech 2022;1(1):e39444

Representation of Time-Relevant Common Data Elements in the Cancer Data Standards Repository: Statistical Evaluation of an Ontological Approach

Representation of Time-Relevant Common Data Elements in the Cancer Data Standards Repository: Statistical Evaluation of an Ontological Approach

The HL7 V3 represents time based on the following five defined classes: point in time, interval, duration, periodic time, and periodic time as sets [16]. The last class allows HL7 V3 to represent cumulative periodic times. Open EHR utilizes date, time, date-time, and duration data types [17,18]. Open EHR allows fields to be missing, allowing for modality to be modeled within the temporal data.

Henry W Chen, Jingcheng Du, Hsing-Yi Song, Xiangyu Liu, Guoqian Jiang, Cui Tao

JMIR Med Inform 2018;6(1):e7