Published on in Vol 7 , No 10 (2019) :October

Preprints (earlier versions) of this paper are available at, first published .
Use of the Chatbot “Vivibot” to Deliver Positive Psychology Skills and Promote Well-Being Among Young People After Cancer Treatment: Randomized Controlled Feasibility Trial

Use of the Chatbot “Vivibot” to Deliver Positive Psychology Skills and Promote Well-Being Among Young People After Cancer Treatment: Randomized Controlled Feasibility Trial

Use of the Chatbot “Vivibot” to Deliver Positive Psychology Skills and Promote Well-Being Among Young People After Cancer Treatment: Randomized Controlled Feasibility Trial


  1. Maher C, Davis C, Curtis R, Short C, Murphy K. A Physical Activity and Diet Program Delivered by Artificially Intelligent Virtual Health Coach: Proof-of-Concept Study. JMIR mHealth and uHealth 2020;8(7):e17558 View
  2. Rauen K, Vetter S, Eisele A, Biskup E, Delsignore A, Rufer M, Weidt S. Internet Cognitive Behavioral Therapy With or Without Face-to-Face Psychotherapy: A 12-Weeks Clinical Trial of Patients With Depression. Frontiers in Digital Health 2020;2 View
  3. Björling E, Thomas K, Rose E, Cakmak M. Exploring Teens as Robot Operators, Users and Witnesses in the Wild. Frontiers in Robotics and AI 2020;7 View
  4. Ahuja A, Reddy V, Marques O. Artificial intelligence and COVID-19: A multidisciplinary approach. Integrative Medicine Research 2020;9(3):100434 View
  5. Al-Rawi A, Shukla V. Bots as Active News Promoters: A Digital Analysis of COVID-19 Tweets. Information 2020;11(10):461 View
  6. Mariamo A, Temcheff C, Léger P, Senecal S, Lau M. Emotional Reactions and Likelihood of Response to Questions Designed for a Mental Health Chatbot Among Adolescents: Experimental Study. JMIR Human Factors 2021;8(1):e24343 View
  7. Dosovitsky G, Pineda B, Jacobson N, Chang C, Escoredo M, Bunge E. Artificial Intelligence Chatbot for Depression: Descriptive Study of Usage. JMIR Formative Research 2020;4(11):e17065 View
  8. te Pas M, Rutten W, Bouwman R, Buise M. User Experience of a Chatbot Questionnaire Versus a Regular Computer Questionnaire: Prospective Comparative Study. JMIR Medical Informatics 2020;8(12):e21982 View
  9. Chan J, Van Blarigan E, Langlais C, Zhao S, Ramsdill J, Daniel K, Macaire G, Wang E, Paich K, Kessler E, Beer T, Lyons K, Broering J, Carroll P, Kenfield S, Winters-Stone K. Feasibility and Acceptability of a Remotely Delivered, Web-Based Behavioral Intervention for Men With Prostate Cancer: Four-Arm Randomized Controlled Pilot Trial. Journal of Medical Internet Research 2020;22(12):e19238 View
  10. Sato A, Haneda E, Suganuma N, Narimatsu H. Preliminary Screening for Hereditary Breast and Ovarian Cancer Using a Chatbot Augmented Intelligence Genetic Counselor: Development and Feasibility Study. JMIR Formative Research 2021;5(2):e25184 View
  11. Sabater S, Rovirosa À, Arenas M. In response to Korreman s. et al. Radiation oncologists are, above all, medical doctors. Clinical and Translational Radiation Oncology 2021;28:116 View
  12. Ye B, Kim J, Suh C, Choi S, Choi M, Kim D, Son B. Development of a Chatbot Program for Follow-Up Management of Workers’ General Health Examinations in Korea: A Pilot Study. International Journal of Environmental Research and Public Health 2021;18(4):2170 View
  13. Rapp A, Curti L, Boldi A. The human side of human-chatbot interaction: A systematic literature review of ten years of research on text-based chatbots. International Journal of Human-Computer Studies 2021;151:102630 View
  14. Psihogios A, King-Dowling S, O’Hagan B, Darabos K, Maurer L, Young J, Fleisher L, Barakat L, Szalda D, Hill-Kayser C, Schwartz L. Contextual Predictors of Engagement in a Tailored mHealth Intervention for Adolescent and Young Adult Cancer Survivors. Annals of Behavioral Medicine 2021;55(12):1220 View
  15. Siddique S, Chow J. Machine Learning in Healthcare Communication. Encyclopedia 2021;1(1):220 View
  16. van Agteren J, Iasiello M, Lo L, Bartholomaeus J, Kopsaftis Z, Carey M, Kyrios M. A systematic review and meta-analysis of psychological interventions to improve mental wellbeing. Nature Human Behaviour 2021;5(5):631 View
  17. Boggiss A, Consedine N, Schache K, Wallace‐Boyd K, Cao N, Hofman P, Serlachius A. Exploring the views of adolescents with type 1 diabetes on digital mental health interventions: What functionality and content do they want?. Diabetic Medicine 2021;38(11) View
  18. Moskowitz J, Addington E, Shiu E, Bassett S, Schuette S, Kwok I, Freedman M, Leykin Y, Saslow L, Cohn M, Cheung E. Facilitator Contact, Discussion Boards, and Virtual Badges as Adherence Enhancements to a Web-Based, Self-guided, Positive Psychological Intervention for Depression: Randomized Controlled Trial. Journal of Medical Internet Research 2021;23(9):e25922 View
  19. Geoghegan L, Scarborough A, Wormald J, Harrison C, Collins D, Gardiner M, Bruce J, Rodrigues J. Automated conversational agents for post-intervention follow-up: a systematic review. BJS Open 2021;5(4) View
  20. Mauriello M, Tantivasadakarn N, Mora-Mendoza M, Lincoln E, Hon G, Nowruzi P, Simon D, Hansen L, Goenawan N, Kim J, Gowda N, Jurafsky D, Paredes P. A Suite of Mobile Conversational Agents for Daily Stress Management (Popbots): Mixed Methods Exploratory Study. JMIR Formative Research 2021;5(9):e25294 View
  21. Siedlikowski S, Noël L, Moynihan S, Robin M. Chloe for COVID-19: The Evolution of an Intelligent Conversational Agent to Address Infodemic Management Needs During the COVID-19 Pandemic (Preprint). Journal of Medical Internet Research 2021 View
  22. Martinengo L, Jabir A, Goh W, Lo N, Ho M, Kowatsch T, Atun R, Michie S, Tudor Car L. Conversational Agents in Health Care: Scoping Review of Their Behavior Change Techniques and Underpinning Theory. Journal of Medical Internet Research 2022;24(10):e39243 View
  23. Chan C, Li F. Developing a natural language-based AI-chatbot for social work training: an illustrative case study. China Journal of Social Work 2023:1 View
  24. Liu H, Peng H, Song X, Xu C, Zhang M. Using AI chatbots to provide self-help depression interventions for university students: A randomized trial of effectiveness. Internet Interventions 2022;27:100495 View
  25. Salsman J, McLouth L, Tooze J, Little-Greene D, Cohn M, Kehoe M, Moskowitz J. An eHealth, Positive Emotion Skills Intervention for Enhancing Psychological Well-Being in Young Adult Cancer Survivors: Results from a Multi-Site, Pilot Feasibility Trial. International Journal of Behavioral Medicine 2023 View
  26. Potts C, Lindström F, Bond R, Mulvenna M, Booth F, Ennis E, Parding K, Kostenius C, Broderick T, Boyd K, Vartiainen A, Nieminen H, Burns C, Bickerdike A, Kuosmanen L, Dhanapala I, Vakaloudis A, Cahill B, Macinnes M, Malcolm M, O'Neill S. A multilingual digital mental health and wellbeing chatbot (ChatPal): pre-post multicenter intervention study (Preprint). Journal of Medical Internet Research 2022 View
  27. Bin Sawad A, Narayan B, Alnefaie A, Maqbool A, Mckie I, Smith J, Yuksel B, Puthal D, Prasad M, Kocaballi A. A Systematic Review on Healthcare Artificial Intelligent Conversational Agents for Chronic Conditions. Sensors 2022;22(7):2625 View
  28. Wilson L, Marasoiu M. The Development and Use of Chatbots in Public Health: Scoping Review. JMIR Human Factors 2022;9(4):e35882 View
  29. Kruzan K, Williams K, Meyerhoff J, Yoo D, O'Dwyer L, De Choudhury M, Mohr D. Social media-based interventions for adolescent and young adult mental health: A scoping review. Internet Interventions 2022;30:100578 View
  30. Xu L, Sanders L, Li K, Chow J. Chatbot for Health Care and Oncology Applications Using Artificial Intelligence and Machine Learning: Systematic Review. JMIR Cancer 2021;7(4):e27850 View
  31. Luca S, Clausen M, Shaw A, Lee W, Krishnapillai S, Adi-Wauran E, Faghfoury H, Costain G, Jobling R, Aronson M, Liston E, Silver J, Shuman C, Chad L, Hayeems R, Bombard Y, Bernier F, Brudno M, Carroll J, Cohn R, Dhalla I, Friedman J, Hewson S, Jamieson T, Kodida R, Laberge A, Lerner-Ellis J, Mamdani M, Marshall C, Osmond M, Pham Q, Reble E, Rudzicz F, Seto E, Shastri-Estrada S, Smith M, Thorpe K, Ungar W. Finding the sweet spot: a qualitative study exploring patients’ acceptability of chatbots in genetic service delivery. Human Genetics 2023;142(3):321 View
  32. Conley C, Raposa E, Bartolotta K, Broner S, Hareli M, Forbes N, Christensen K, Assink M. The Impact of Mobile Technology-Delivered Interventions on Youth Well-being: Systematic Review and 3-Level Meta-analysis. JMIR Mental Health 2022;9(7):e34254 View
  33. Dhinagaran D, Martinengo L, Ho M, Joty S, Kowatsch T, Atun R, Tudor Car L. Designing, Developing, Evaluating, and Implementing a Smartphone-Delivered, Rule-Based Conversational Agent (DISCOVER): Development of a Conceptual Framework. JMIR mHealth and uHealth 2022;10(10):e38740 View
  34. Boucher E, Harake N, Ward H, Stoeckl S, Vargas J, Minkel J, Parks A, Zilca R. Artificially intelligent chatbots in digital mental health interventions: a review. Expert Review of Medical Devices 2021;18(sup1):37 View
  35. Chandeying N, Thongseiratch T. Online Interventions to Improve Mental Health of Pediatric, Adolescent, and Young Adult Cancer Survivors: A Systematic Review and Meta-Analysis. Frontiers in Psychiatry 2021;12 View
  36. Dorfman C, Shelby R, Stalls J, Somers T, Keefe F, Vilardaga J, Winger J, Mitchell K, Ehren C, Oeffinger K. Improving Symptom Management for Survivors of Young Adult Cancer: Development of a Novel Intervention. Journal of Adolescent and Young Adult Oncology 2022 View
  37. Chua J, Choolani M, Chee C, Chan Y, Lalor J, Chong Y, Shorey S. Insights of Parents and Parents‐To‐Be in Using Chatbots to Improve Their Preconception, Pregnancy, and Postpartum Health: A Mixed Studies Review. Journal of Midwifery & Women's Health 2023 View
  38. Benedict C, Lazard A, Smith S, Agrawal A, Collins M, Love B. User experiences, usability, and social presence of a peer-to-peer support app: survey of young adults affected by cancer. Journal of Applied Communication Research 2021;49(5):497 View
  39. Ali F, Zhang Q, Tauni M, Shahzad K. Social Chatbot: My Friend in My Distress. International Journal of Human–Computer Interaction 2023:1 View
  40. Kim Y, DeLisa J, Chung Y, Shapiro N, Kolar Rajanna S, Barbour E, Loeb J, Turner J, Daley S, Skowlund J, Krishnan J. Recruitment in a research study via chatbot versus telephone outreach: a randomized trial at a minority-serving institution. Journal of the American Medical Informatics Association 2021;29(1):149 View
  41. Lee K, Kim S, Kim S, Yoo S, Sung J, Oh E, Kim N, Lee J. Digital Health Interventions for Adult Patients With Cancer Evaluated in Randomized Controlled Trials: Scoping Review. Journal of Medical Internet Research 2023;25:e38333 View
  42. Ma D, Orner D, Ghaly M, Parashar B, Ames J, Chen W, Potters L, Teckie S. Automated health chats for symptom management of head and neck cancer patients undergoing radiation therapy. Oral Oncology 2021;122:105551 View
  43. Donaldson S, van Zyl L, Donaldson S. PERMA+4: A Framework for Work-Related Wellbeing, Performance and Positive Organizational Psychology 2.0. Frontiers in Psychology 2022;12 View
  44. Williams R, Hopkins S, Frampton C, Holt-Quick C, Merry S, Stasiak K. 21-Day Stress Detox: Open Trial of a Universal Well-Being Chatbot for Young Adults. Social Sciences 2021;10(11):416 View
  45. Ghazal L, Merriman J, Santacroce S, Fletcher J, Wright F, Dickson V. Exploration of Relationships Between Symptoms, Work Characteristics, and Quality of Life in Young Adult Hematologic Cancer Survivors. Journal of Adolescent and Young Adult Oncology 2022;11(5):530 View
  46. Koulouri T, Macredie R, Olakitan D. Chatbots to Support Young Adults’ Mental Health: An Exploratory Study of Acceptability. ACM Transactions on Interactive Intelligent Systems 2022;12(2):1 View
  47. He Y, Yang L, Qian C, Li T, Su Z, Zhang Q, Hou X. Conversational Agent Interventions for Mental Health Problems: Systematic Review and Meta-analysis of Randomized Controlled Trials. Journal of Medical Internet Research 2023;25:e43862 View
  48. Mizrach H, Goshe B, Park E, Recklitis C, Greer J, Chang Y, Frederick N, Abrams A, Tower M, Walsh E, Huang M, Kenney L, Homans A, Miller K, Denninger J, Usmani G, Peppercorn J, Perez G. Randomized Waitlist-Control Trial of a Web-Based Stress-Management and Resiliency Program for Adolescent and Young Adult Cancer Survivors: Protocol for the Bounce Back Study. JMIR Research Protocols 2022;11(1):e34033 View
  49. Briggs L, Labban M, Alkhatib K, Nguyen D, Cole A, Trinh Q. Digital technologies in cancer care: a review from the clinician's perspective. Journal of Comparative Effectiveness Research 2022;11(7):533 View
  50. Luo B, Lau R, Li C, Si Y. A critical review of state‐of‐the‐art chatbot designs and applications. WIREs Data Mining and Knowledge Discovery 2022;12(1) View
  51. Schick A, Feine J, Morana S, Maedche A, Reininghaus U. Validity of Chatbot Use for Mental Health Assessment: Experimental Study. JMIR mHealth and uHealth 2022;10(10):e28082 View
  52. Boggiss A, Consedine N, Hopkins S, Silvester C, Jefferies C, Hofman P, Serlachius A. Improving the Well-being of Adolescents With Type 1 Diabetes During the COVID-19 Pandemic: Qualitative Study Exploring Acceptability and Clinical Usability of a Self-compassion Chatbot. JMIR Diabetes 2023;8:e40641 View
  53. Terblanche N, Molyn J, de Haan E, Nilsson V, Triberti S. Comparing artificial intelligence and human coaching goal attainment efficacy. PLOS ONE 2022;17(6):e0270255 View
  54. He Y, Yang L, Zhu X, Wu B, Zhang S, Qian C, Tian T. Mental Health Chatbot for Young Adults With Depressive Symptoms During the COVID-19 Pandemic: Single-Blind, Three-Arm Randomized Controlled Trial. Journal of Medical Internet Research 2022;24(11):e40719 View
  55. Loveys K, Sagar M, Pickering I, Broadbent E. A Digital Human for Delivering a Remote Loneliness and Stress Intervention to At-Risk Younger and Older Adults During the COVID-19 Pandemic: Randomized Pilot Trial. JMIR Mental Health 2021;8(11):e31586 View
  56. May R, Denecke K. Security, privacy, and healthcare-related conversational agents: a scoping review. Informatics for Health and Social Care 2022;47(2):194 View
  57. Wake D, Smith D, Kazi S, Dunnenberger H. Pharmacogenomic Clinical Decision Support: A Review, How‐to Guide, and Future Vision. Clinical Pharmacology & Therapeutics 2022;112(1):44 View
  58. Roca S, Lozano M, García J, Alesanco Á. Validation of a Virtual Assistant for Improving Medication Adherence in Patients with Comorbid Type 2 Diabetes Mellitus and Depressive Disorder. International Journal of Environmental Research and Public Health 2021;18(22):12056 View
  59. van Bussel M, Odekerken–Schröder G, Ou C, Swart R, Jacobs M. Analyzing the determinants to accept a virtual assistant and use cases among cancer patients: a mixed methods study. BMC Health Services Research 2022;22(1) View
  60. Dwyer T, Hoit G, Burns D, Higgins J, Chang J, Whelan D, Kiroplis I, Chahal J. Use of an Artificial Intelligence Conversational Agent (Chatbot) for Hip Arthroscopy Patients Following Surgery. Arthroscopy, Sports Medicine, and Rehabilitation 2023;5(2):e495 View
  61. Tawfik E, Ghallab E, Moustafa A. A nurse versus a chatbot ‒ the effect of an empowerment program on chemotherapy-related side effects and the self-care behaviors of women living with breast Cancer: a randomized controlled trial. BMC Nursing 2023;22(1) View
  62. Jabir A, Martinengo L, Lin X, Torous J, Subramaniam M, Tudor Car L. Evaluating Conversational Agents for Mental Health: Scoping Review of Outcomes and Outcome Measurement Instruments. Journal of Medical Internet Research 2023;25:e44548 View
  63. Li Y, Liang S, Zhu B, Liu X, Li J, Chen D, Qin J, Bressington D. Feasibility and effectiveness of artificial intelligence-driven conversational agents in healthcare interventions: A systematic review of randomized controlled trials. International Journal of Nursing Studies 2023;143:104494 View
  64. Nguyen H, Lopez J, Homer B, Ali A, Ahn J. Reminders, reflections, and relationships: insights from the design of a chatbot for college advising. Information and Learning Sciences 2023;124(3/4):128 View
  65. Haque M, Rubya S. An Overview of Chatbot Based Mobile Mental Health Applica-tions: Insights from App Description and User Reviews (Preprint). JMIR mHealth and uHealth 2022 View

Books/Policy Documents

  1. van Wezel M, Croes E, Antheunis M. Chatbot Research and Design. View
  2. Félix B, Ribeiro J. Chatbot Research and Design. View
  3. Bickmore T, O'Leary T. Digital Therapeutics for Mental Health and Addiction. View