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Skip search results from other journals and go to results- 622 Journal of Medical Internet Research
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The number of cases was calculated using the R-tool (Michael C. Donohue) longpower [48]. For the secondary outcomes, we calculated a minimal detectable effect size of Cohen d=–0.46 with 80% power and an α level of .0125 (Bonferroni-Holm adjustment) based on a post hoc power analysis of the WSAS with simr (Peter Green) [49].
Randomization in 1:1 ratio without stratification or blocks was done automatically by a computer-generated code. Participants were automatically informed of their group via email.
J Med Internet Res 2025;27:e54062
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Several recent Canadian population-based studies have shown that many patients at high CVD risk continue to have low-density lipoprotein cholesterol (LDL-C) levels well above the guideline targets [2,3]. LDL-C has been extensively studied and described as a causal factor for CVD [4]. LDL-C levels above the target can result from multiple factors such as insufficient LDL-C lowering with statins, statin-related side effects, suboptimal medication adherence, and treatment inertia [5].
JMIR Cardio 2025;9:e58124
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