Prescribable Digital Interventions (Digital Therapeutics)

Prescribable Digital Interventions (predominantly mobile apps) are sometimes also called Digital Therapeutics (however, the terminology is inconsistent, with the term "digital therapeutics" sometimes also being applied to non-prescribable interventions). In JMIR journals we prefer to limit the term "digital therapeutics" for prescribable apps, e.g. DiGA in Germany.

See also:

* Digital Therapeutics (Journal of Participatory Medicine)

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Years in this theme: All years 2025 2024 2023 2022 2021 2020

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Articles published in this theme: 32 (scroll down to load remaining articles)

2025

Interventions for Digital Addiction: Umbrella Review of Meta-Analyses

Peng Lu, Jiamin Qiu, Shiqi Huang, Xinman Wang, Shasha Han, Sui Zhu, Youjing Ning, Fang-fang Zeng, Yuan Yuan

J Med Internet Res 2025 (Feb 11); 27:e59656

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Implementing Internet-Delivered Cognitive Behavioral Therapy for Depression and Anxiety in Adults: Systematic Review

Implementing Internet-Delivered Cognitive Behavioral Therapy for Depression and Anxiety in Adults: Systematic Review

Daniel Duffy, Derek Richards, Garrett Hisler, Ladislav Timulak

J Med Internet Res 2025 (Jan 28); 27:e47927

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Establishment and Maintenance of a Digital Therapeutic Alliance in People Living With Negative Symptoms of Schizophrenia: Two Exploratory Single-Arm Studies

Establishment and Maintenance of a Digital Therapeutic Alliance in People Living With Negative Symptoms of Schizophrenia: Two Exploratory Single-Arm Studies

Cassandra Snipes, Cornelia Dorner‑Ciossek, Brendan D Hare, Olya Besedina, Tim Campellone, Mariya Petrova, Shaheen E Lakhan, Abhishek Pratap

JMIR Ment Health 2025 (Jan 27); 12:e64959

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Digital Frequency Customized Relieving Sound for Chronic Subjective Tinnitus Management: Prospective Controlled Study

Digital Frequency Customized Relieving Sound for Chronic Subjective Tinnitus Management: Prospective Controlled Study

Dongmei Tang, Yuzhu Peng, Dantong Gu, Yongzhen Wu, Huawei Li

J Med Internet Res 2025 (Jan 17); 27:e60150

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Mapping the Landscape of Digital Health Intervention Strategies: 25-Year Synthesis

Mapping the Landscape of Digital Health Intervention Strategies: 25-Year Synthesis

Shiyu Liu, Jingru Ma, Meichen Sun, Chao Zhang, Yujing Gao, Jinghong Xu

J Med Internet Res 2025 (Jan 13); 27:e59027

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2024

Effectiveness of an Internet-Based Acceptance and Commitment Therapy Intervention for Reducing Psychological Distress in Health Care Professionals: Randomized Controlled Trial

Effectiveness of an Internet-Based Acceptance and Commitment Therapy Intervention for Reducing Psychological Distress in Health Care Professionals: Randomized Controlled Trial

Lin Zhang, Shuang Huang, Sha Liu, Yuanxiu Huang, Shan Chen, Jinsong Hu, Mingzhong Xu

J Med Internet Res 2024 (Dec 18); 26:e59093

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Clinical Use of Mental Health Digital Therapeutics in a Large Health Care Delivery System: Retrospective Patient Cohort Study and Provider Survey

Clinical Use of Mental Health Digital Therapeutics in a Large Health Care Delivery System: Retrospective Patient Cohort Study and Provider Survey

Samuel J Ridout, Kathryn K Ridout, Teresa Y Lin, Cynthia I Campbell

JMIR Ment Health 2024 (Oct 02); 11:e56574

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Digital Health Applications (DiGAs) on a Fast Track: Insights From a Data-Driven Analysis of Prescribable Digital Therapeutics in Germany From 2020 to Mid-2024

Digital Health Applications (DiGAs) on a Fast Track: Insights From a Data-Driven Analysis of Prescribable Digital Therapeutics in Germany From 2020 to Mid-2024

Moritz Goeldner, Sara Gehder

J Med Internet Res 2024 (Aug 29); 26:e59013

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eHealth-Integrated Psychosocial and Physical Interventions for Chronic Pain in Older Adults: Scoping Review

eHealth-Integrated Psychosocial and Physical Interventions for Chronic Pain in Older Adults: Scoping Review

Annalisa De Lucia, Cinzia Perlini, Alessandro Chiarotto, Sara Pachera, Ilenia Pasini, Lidia Del Piccolo, Valeria Donisi

J Med Internet Res 2024 (Jul 29); 26:e55366

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Problems and Barriers Related to the Use of mHealth Apps From the Perspective of Patients: Focus Group and Interview Study

Problems and Barriers Related to the Use of mHealth Apps From the Perspective of Patients: Focus Group and Interview Study

Godwin Denk Giebel, Carina Abels, Felix Plescher, Christian Speckemeier, Nils Frederik Schrader, Kirstin Börchers, Jürgen Wasem, Silke Neusser, Nikola Blase

J Med Internet Res 2024 (Apr 23); 26:e49982

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Evidence of How Physicians and Their Patients Adopt mHealth Apps in Germany: Exploratory Qualitative Study

Evidence of How Physicians and Their Patients Adopt mHealth Apps in Germany: Exploratory Qualitative Study

Tanja Schroeder, Maximilian Haug, Andrew Georgiou, Karla Seaman, Heiko Gewald

JMIR Mhealth Uhealth 2024 (Jan 17); 12:e48345

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2023

Stakeholders’ Perceptions Regarding Digital Therapeutics Reimbursement in South Korea: Qualitative Study

Stakeholders’ Perceptions Regarding Digital Therapeutics Reimbursement in South Korea: Qualitative Study

Boram Sim, Jin Han Ju, Byungsoo Kim, Jin Yong Lee

JMIR Mhealth Uhealth 2023 (Oct 30); 11:e47407

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Postmarketing Follow-Up of a Digital Home Exercise Program for Back, Hip, and Knee Pain: Retrospective Observational Study With a Time-Series and Matched-Pair Analysis

Postmarketing Follow-Up of a Digital Home Exercise Program for Back, Hip, and Knee Pain: Retrospective Observational Study With a Time-Series and Matched-Pair Analysis

Gisbert Wilhelm Teepe, Tobias Kowatsch, Felix Patricius Hans, Leo Benning

J Med Internet Res 2023 (Feb 27); 25:e43775

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Interventions Aimed at Enhancing Health Care Providers’ Behavior Toward the Prescription of Mobile Health Apps: Systematic Review

Interventions Aimed at Enhancing Health Care Providers’ Behavior Toward the Prescription of Mobile Health Apps: Systematic Review

Ohoud Alkhaldi, Brian McMillan, Noha Maddah, John Ainsworth

JMIR Mhealth Uhealth 2023 (Feb 27); 11:e43561

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2022

Preliminary Use and Outcome Data of a Digital Home Exercise Program for Back, Hip, and Knee Pain: Retrospective Observational Study With a Time Series and Matched Analysis

Preliminary Use and Outcome Data of a Digital Home Exercise Program for Back, Hip, and Knee Pain: Retrospective Observational Study With a Time Series and Matched Analysis

Gisbert Wilhelm Teepe, Tobias Kowatsch, Felix Patricius Hans, Leo Benning

JMIR Mhealth Uhealth 2022 (Dec 02); 10(12):e38649

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Health Care Workers’ Need for Headspace: Findings From a Multisite Definitive Randomized Controlled Trial of an Unguided Digital Mindfulness-Based Self-help App to Reduce Healthcare Worker Stress

Health Care Workers’ Need for Headspace: Findings From a Multisite Definitive Randomized Controlled Trial of an Unguided Digital Mindfulness-Based Self-help App to Reduce Healthcare Worker Stress

Heather Taylor, Kate Cavanagh, Andy P Field, Clara Strauss

JMIR Mhealth Uhealth 2022 (Aug 25); 10(8):e31744

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Review and Analysis of German Mobile Apps for Inflammatory Bowel Disease Management Using the Mobile Application Rating Scale: Systematic Search in App Stores and Content Analysis

Review and Analysis of German Mobile Apps for Inflammatory Bowel Disease Management Using the Mobile Application Rating Scale: Systematic Search in App Stores and Content Analysis

Maximilian Gerner, Nicolas Vuillerme, Timothée Aubourg, Eva-Maria Messner, Yannik Terhorst, Verena Hörmann, Ingo Ganzleben, Hannah Schenker, Georg Schett, Raja Atreya, Markus F Neurath, Johannes Knitza, Till Orlemann

JMIR Mhealth Uhealth 2022 (May 03); 10(5):e31102

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Problems and Barriers Related to the Use of Digital Health Applications: Protocol for a Scoping Review

Problems and Barriers Related to the Use of Digital Health Applications: Protocol for a Scoping Review

Godwin Denk Giebel, Christian Speckemeier, Carina Abels, Kirstin Börchers, Jürgen Wasem, Nikola Blase, Silke Neusser

JMIR Res Protoc 2022 (Apr 21); 11(4):e32702

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2021

Clinical Efficacy and Psychological Mechanisms of an App-Based Digital Therapeutic for Generalized Anxiety Disorder: Randomized Controlled Trial

Clinical Efficacy and Psychological Mechanisms of an App-Based Digital Therapeutic for Generalized Anxiety Disorder: Randomized Controlled Trial

Alexandra Roy, Elizabeth A Hoge, Pablo Abrante, Susan Druker, Tao Liu, Judson A Brewer

J Med Internet Res 2021 (Dec 02); 23(12):e26987

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Tools for Evaluating the Content, Efficacy, and Usability of Mobile Health Apps According to the Consensus-Based Standards for the Selection of Health Measurement Instruments: Systematic Review

Tools for Evaluating the Content, Efficacy, and Usability of Mobile Health Apps According to the Consensus-Based Standards for the Selection of Health Measurement Instruments: Systematic Review

Antonio Muro-Culebras, Adrian Escriche-Escuder, Jaime Martin-Martin, Cristina Roldán-Jiménez, Irene De-Torres, Maria Ruiz-Muñoz, Manuel Gonzalez-Sanchez, Fermin Mayoral-Cleries, Attila Biró, Wen Tang, Borjanka Nikolova, Alfredo Salvatore, Antonio Ignacio Cuesta-Vargas

JMIR Mhealth Uhealth 2021 (Dec 01); 9(12):e15433

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