Prescribable Digital Interventions (Digital Therapeutics)

Articles published in this theme: 52 (scroll down to load remaining articles)

2026

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Strength of Evidence to Support Decision-Making on the Use of Digital Mental Health Technologies in NICE Evaluations: Cross-Sectional Analysis of Studies

Gareth Hopkin, Holly Coole, Francesca Edelmann, John Powell, Mark Salmon, Sophie Cooper

JMIR Ment Health 2026 (Apr 07); 13:e85635

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Locomotive Syndrome Digital Therapeutics Provided via a Smartphone App: Proof-of-Concept Single-Group Trial Study

Tatsuru Sonobe, Itaru Ogawa, Takahiro Seki, Kosuke Watanabe, Yota Kaneko, Takeru Yokota, Taro Mawatari, Satoru Harada, Yasumichi Kadowaki, Youhei Takenaka, Yoshihiro Matsumoto

JMIR Aging 2026 (Mar 13); 9:e86174

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An Early-Stage Digital Therapeutic Intervention to Enhance Affective Response During Physical Activity Among Adults With Overweight or Obesity: Benchmark-Driven Formative Testing Study

Rachel Crosley-Lyons, Lori Hatzinger, Micaela Hewus, Wei-Lin Wang, Delfien Van Dyck, Jimi Huh, Eric Hekler, Genevieve F Dunton

JMIR Hum Factors 2026 (Feb 20); 13:e71472

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Developing and Evaluating a WeChat-Based Applet Fluid Intake Reminder on Enhancing Fluid Adherence in Postoperative Patients With Urinary Calculi: Protocol for a Randomized Controlled Trial

Xue Zhou, Tongyao Wang, Qian Chen

JMIR Res Protoc 2026 (Feb 19); 15:e80214

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Evaluating the Safety and Performance of the KidneYou App for Chronic Kidney Disease: Protocol for an Italian Multicenter, Randomized, Open-Label, Premarket Study

Cesira Cafiero, Marco Gnesi, Anna Rita Maurizi, Andreana Foresta, Massimo Beccaria, Giorgia Campilongo, Marco Fiorentino, Paola Maria Acquaviva, Francesca Mastromauro, Marco Gorini, Loreto Gesualdo

JMIR Res Protoc 2026 (Feb 19); 15:e75306

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2025

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Effect of a Mobile Health Intervention in the Management of Hypertension: Open-Label Cluster-Randomized Trial

Xiaoli Zhao, Qiang Zhao, Qinxian Yang, Yan Li, Xiaona Xing, Xiaoping Li

JMIR Mhealth Uhealth 2025 (Dec 24); 13:e72416

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Transdiagnostic App–Based Cognitive Bias Modification Intervention for Paranoia (Successful Treatment of Paranoia; STOP): Protocol for a Mixed Methods Process Evaluation Embedded in a Randomized Controlled Trial

Chloe Hampshire, Charlotte Dack, Laura Eid, Carolina Fialho, Alexandra Kenny, Hannah Scott, Rayan Taher, Theresa Taylor, Jenny Yiend, Pamela Jacobsen

JMIR Res Protoc 2025 (Dec 22); 14:e81167

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Cost-Utility Analysis and Value-Based Pricing of Digital Therapeutics for Pulmonary Rehabilitation in Chronic Respiratory Disease: Economic Evaluation Based on a Randomized Controlled Trial

Hyeonjung Park, Minseol Jang, Daehyun Kim, Chul Kim, Jun Hyeong Song, Ju Hyun Oh, Chin Kook Rhee, Jae Ha Lee, Hee-Eun Choi, Hae Sun Suh

J Med Internet Res 2025 (Dec 15); 27:e73739

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Efficacy and Compliance of a Working Memory Multitasking Task Mobile Intervention for Children With Attention-Deficit/Hyperactivity Disorder: Single-Arm, Pre-Post Pilot Study

Minyoung Jung, Jimin Woo, Sung Jin Kim, You Bin Lim, Younglae Kim, Dongwon Kang, Jung-sang Min, Bung-Nyun Kim

JMIR Hum Factors 2025 (Oct 28); 12:e70479

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Evaluating the Efficacy of a Digital Therapeutic Intervention for Temporomandibular Disorders: Multicenter, Randomized, Sham-Controlled Trial

Sang-Yoon Park, Sung-Woon On, Sangmin Yi, Sung-Ah Che, Bongju Kim, Soo-Hwan Byun, Byoung-Eun Yang

J Med Internet Res 2025 (Oct 24); 27:e83545

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Effectiveness, Engagement, and Safety of a Digital Therapeutic (CT-155/BI 3972080) for Treating Negative Symptoms in People With Schizophrenia: Protocol for the Phase 3 CONVOKE Randomized Controlled Trial

Shaheen E Lakhan, Cornelia Dorner-Ciossek, Olya Besedina, Faith Dickerson, Claudia Hastedt, Ridwana Isla, René S Kahn, Jean-Pierre Lindenmayer, Ruchi Mehta, Cassandra Snipes, Austin Speier, Wenbo Tang, Bailey Willis, Jamie Winderbaum Fernandez, Christoph von der Goltz, Abhishek Pratap

JMIR Res Protoc 2025 (Oct 07); 14:e81293

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Validating the Efficacy of a Mobile Digital Therapeutic for Insomnia (WELT-I): Randomized Controlled Decentralized Clinical Trial

Kyung Mee Park, Suonaa Lee, Yujin Lee, Daa Un Moon, Eun Lee

J Med Internet Res 2025 (Sep 23); 27:e70722

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A Design Framework for Microintervention Software Technology in Digital Health: Critical Interpretive Synthesis

Dan Roland Persson, Mel Ramasawmy, Nushrat Khan, Amitava Banerjee, Ann Blandford, Jakob Eyvind Bardram, Per Bækgaard

J Med Internet Res 2025 (Sep 12); 27:e72658

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Long-Term Feasibility and Outcomes of a Digital Health Program to Improve Liver Fat and Cardiometabolic Markers in Individuals With Nonalcoholic Fatty Liver Disease: Prospective Single-Arm Feasibility Study

Sigridur Björnsdottir, Hildigunnur Ulfsdottir, Elias Freyr Gudmundsson, Bartosz Dobies, Kolbrun Sveinsdottir, Ari Pall Isberg, Gudlaug E A Magnusdottir, Thrudur Gunnarsdottir, Tekla Karlsdottir, Gudlaug Bjornsdottir, Sigurdur Sigurdsson, Saemundur Oddsson, Vilmundur Gudnason

JMIR Cardio 2025 (Sep 12); 9:e72074

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Development of a Social Communication Intervention Mobile App for Adolescents With Autism Spectrum Disorder and Social Communication Disorder: Protocol for a Pilot Randomized Clinical Trial

Enn Young Lee, SungJa Cho, Ran Ju, Hyunjae Kim, Tae Young Choi, Jae Hyun Yoo, Yoo-Sook Joung

JMIR Res Protoc 2025 (Sep 09); 14:e66419

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Concepts for the Integration and Implementation of mHealth Apps for Patients With Mental Disorders: Scoping Review

Felix Plescher, Klemens Höfer, Jürgen Wasem, Anna Bußmann, Stefanie Solar, Michael Minor, Sarah Schlierenkamp, Dieter Best, Josepha Katzmann, Enno Maaß, Udo Schneider, Anja Wadeck, Sophia Zander, Carina Abels

J Med Internet Res 2025 (Sep 08); 27:e66340

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Personalization of AI Using Personal Foundation Models Can Lead to More Precise Digital Therapeutics

Peter Washington

JMIR AI 2025 (Aug 21); 4:e55530

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Magnitude of the Digital Placebo Effect and Its Moderators on Generalized Anxiety Symptoms: Systematic Review and Meta-Analysis

Takashi Hosono, Rinka Tsutsumi, Yuki Niwa, Masuo Kondoh

J Med Internet Res 2025 (Jul 31); 27:e74905

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Combined Use of Digital and Analog Physical Therapy in Patients With Musculoskeletal Disorders and Indicators of Chronicity: German Claims Data Analysis

Silke Frey, Annika Schmitz, Udo Schneider, Linda Kerkemeyer, Birgitta Weltermann

JMIR Mhealth Uhealth 2025 (Jun 09); 13:e63935

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Digital Therapeutics in China: Comprehensive Review

Nan Jiang, Xiru Yu, Yuxi Yang, Guanqiao Li, Chanchan He, Man Ping Wang, Yih Chung Tham, Tien Yin Wong, Keqin Rao

J Med Internet Res 2025 (May 27); 27:e70955

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