Prescribable Digital Interventions (Digital Therapeutics)

Articles published in 2025 in this theme: 20 (scroll down to load remaining articles)

2025

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Effect of a Mobile Health Intervention in the Management of Hypertension: Open-Label Cluster-Randomized Trial

Xiaoli Zhao, Qiang Zhao, Qinxian Yang, Yan Li, Xiaona Xing, Xiaoping Li

JMIR Mhealth Uhealth 2025 (Dec 24); 13:e72416

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Transdiagnostic App–Based Cognitive Bias Modification Intervention for Paranoia (Successful Treatment of Paranoia; STOP): Protocol for a Mixed Methods Process Evaluation Embedded in a Randomized Controlled Trial

Chloe Hampshire, Charlotte Dack, Laura Eid, Carolina Fialho, Alexandra Kenny, Hannah Scott, Rayan Taher, Theresa Taylor, Jenny Yiend, Pamela Jacobsen

JMIR Res Protoc 2025 (Dec 22); 14:e81167

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Cost-Utility Analysis and Value-Based Pricing of Digital Therapeutics for Pulmonary Rehabilitation in Chronic Respiratory Disease: Economic Evaluation Based on a Randomized Controlled Trial

Hyeonjung Park, Minseol Jang, Daehyun Kim, Chul Kim, Jun Hyeong Song, Ju Hyun Oh, Chin Kook Rhee, Jae Ha Lee, Hee-Eun Choi, Hae Sun Suh

J Med Internet Res 2025 (Dec 15); 27:e73739

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Efficacy and Compliance of a Working Memory Multitasking Task Mobile Intervention for Children With Attention-Deficit/Hyperactivity Disorder: Single-Arm, Pre-Post Pilot Study

Minyoung Jung, Jimin Woo, Sung Jin Kim, You Bin Lim, Younglae Kim, Dongwon Kang, Jung-sang Min, Bung-Nyun Kim

JMIR Hum Factors 2025 (Oct 28); 12:e70479

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Evaluating the Efficacy of a Digital Therapeutic Intervention for Temporomandibular Disorders: Multicenter, Randomized, Sham-Controlled Trial

Sang-Yoon Park, Sung-Woon On, Sangmin Yi, Sung-Ah Che, Bongju Kim, Soo-Hwan Byun, Byoung-Eun Yang

J Med Internet Res 2025 (Oct 24); 27:e83545

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Effectiveness, Engagement, and Safety of a Digital Therapeutic (CT-155/BI 3972080) for Treating Negative Symptoms in People With Schizophrenia: Protocol for the Phase 3 CONVOKE Randomized Controlled Trial

Shaheen E Lakhan, Cornelia Dorner-Ciossek, Olya Besedina, Faith Dickerson, Claudia Hastedt, Ridwana Isla, René S Kahn, Jean-Pierre Lindenmayer, Ruchi Mehta, Cassandra Snipes, Austin Speier, Wenbo Tang, Bailey Willis, Jamie Winderbaum Fernandez, Christoph von der Goltz, Abhishek Pratap

JMIR Res Protoc 2025 (Oct 07); 14:e81293

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Validating the Efficacy of a Mobile Digital Therapeutic for Insomnia (WELT-I): Randomized Controlled Decentralized Clinical Trial

Kyung Mee Park, Suonaa Lee, Yujin Lee, Daa Un Moon, Eun Lee

J Med Internet Res 2025 (Sep 23); 27:e70722

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A Design Framework for Microintervention Software Technology in Digital Health: Critical Interpretive Synthesis

Dan Roland Persson, Mel Ramasawmy, Nushrat Khan, Amitava Banerjee, Ann Blandford, Jakob Eyvind Bardram, Per Bækgaard

J Med Internet Res 2025 (Sep 12); 27:e72658

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Long-Term Feasibility and Outcomes of a Digital Health Program to Improve Liver Fat and Cardiometabolic Markers in Individuals With Nonalcoholic Fatty Liver Disease: Prospective Single-Arm Feasibility Study

Sigridur Björnsdottir, Hildigunnur Ulfsdottir, Elias Freyr Gudmundsson, Bartosz Dobies, Kolbrun Sveinsdottir, Ari Pall Isberg, Gudlaug E A Magnusdottir, Thrudur Gunnarsdottir, Tekla Karlsdottir, Gudlaug Bjornsdottir, Sigurdur Sigurdsson, Saemundur Oddsson, Vilmundur Gudnason

JMIR Cardio 2025 (Sep 12); 9:e72074

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Development of a Social Communication Intervention Mobile App for Adolescents With Autism Spectrum Disorder and Social Communication Disorder: Protocol for a Pilot Randomized Clinical Trial

Enn Young Lee, SungJa Cho, Ran Ju, Hyunjae Kim, Tae Young Choi, Jae Hyun Yoo, Yoo-Sook Joung

JMIR Res Protoc 2025 (Sep 09); 14:e66419

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Concepts for the Integration and Implementation of mHealth Apps for Patients With Mental Disorders: Scoping Review

Felix Plescher, Klemens Höfer, Jürgen Wasem, Anna Bußmann, Stefanie Solar, Michael Minor, Sarah Schlierenkamp, Dieter Best, Josepha Katzmann, Enno Maaß, Udo Schneider, Anja Wadeck, Sophia Zander, Carina Abels

J Med Internet Res 2025 (Sep 08); 27:e66340

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Personalization of AI Using Personal Foundation Models Can Lead to More Precise Digital Therapeutics

Peter Washington

JMIR AI 2025 (Aug 21); 4:e55530

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Magnitude of the Digital Placebo Effect and Its Moderators on Generalized Anxiety Symptoms: Systematic Review and Meta-Analysis

Takashi Hosono, Rinka Tsutsumi, Yuki Niwa, Masuo Kondoh

J Med Internet Res 2025 (Jul 31); 27:e74905

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Combined Use of Digital and Analog Physical Therapy in Patients With Musculoskeletal Disorders and Indicators of Chronicity: German Claims Data Analysis

Silke Frey, Annika Schmitz, Udo Schneider, Linda Kerkemeyer, Birgitta Weltermann

JMIR Mhealth Uhealth 2025 (Jun 09); 13:e63935

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Digital Therapeutics in China: Comprehensive Review

Nan Jiang, Xiru Yu, Yuxi Yang, Guanqiao Li, Chanchan He, Man Ping Wang, Yih Chung Tham, Tien Yin Wong, Keqin Rao

J Med Internet Res 2025 (May 27); 27:e70955

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Interventions for Digital Addiction: Umbrella Review of Meta-Analyses

Peng Lu, Jiamin Qiu, Shiqi Huang, Xinman Wang, Shasha Han, Sui Zhu, Youjing Ning, Fang-fang Zeng, Yuan Yuan

J Med Internet Res 2025 (Feb 11); 27:e59656

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Implementing Internet-Delivered Cognitive Behavioral Therapy for Depression and Anxiety in Adults: Systematic Review

Daniel Duffy, Derek Richards, Garrett Hisler, Ladislav Timulak

J Med Internet Res 2025 (Jan 28); 27:e47927

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Establishment and Maintenance of a Digital Therapeutic Alliance in People Living With Negative Symptoms of Schizophrenia: Two Exploratory Single-Arm Studies

Cassandra Snipes, Cornelia Dorner‑Ciossek, Brendan D Hare, Olya Besedina, Tim Campellone, Mariya Petrova, Shaheen E Lakhan, Abhishek Pratap

JMIR Ment Health 2025 (Jan 27); 12:e64959

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Digital Frequency Customized Relieving Sound for Chronic Subjective Tinnitus Management: Prospective Controlled Study

Dongmei Tang, Yuzhu Peng, Dantong Gu, Yongzhen Wu, Huawei Li

J Med Internet Res 2025 (Jan 17); 27:e60150

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Mapping the Landscape of Digital Health Intervention Strategies: 25-Year Synthesis

Shiyu Liu, Jingru Ma, Meichen Sun, Chao Zhang, Yujing Gao, Jinghong Xu

J Med Internet Res 2025 (Jan 13); 27:e59027

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