Digital Biomarkers and Digital Phenotyping

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Years in this theme: All years 2026 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016

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Articles published in this theme: 381 (scroll down to load remaining articles)

2026

Two smiling women in athletic wear enjoying an outdoor conversation

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AI-Powered Framework for Personalized Prescription of Physical Activity in Aging: Proposing PEPHA, a framework for Personalized Phenotyping for Aging

Igor Matias, Melanie Mack, Matthias Kliegel, Katarzyna Wac

JMIR AI 2026 (Oct 06); 5:e95123

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Doctor holding tablet with medical questionnaire for patient intake

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Electronic Health Record–Based Phenotyping for Obsessive-Compulsive Disorder: Algorithm Development and Multicenter Validation Study

Bo Wang, Tyne W Miller-Fleming, Dongmei Yu, Donald Hucks, Emily Gantz, Rebecca Johnston, Angela Maxwell-Horn, Nancy Cox, James Sutcliffe, Carol A Mathews, Evonne McArthur, Patrick L McGuire, Dia Kabir, Ashley Dankese, Evan J Giangrande, Rebecca G Fortgang, Shirley B Wang, Rakesh Karmacharya, Joshua L Roffman, Jeremiah M Scharf, Jordan W Smoller, Takahiro Soda, James J Crowley, Lea K Davis

JMIR Ment Health 2026 (Oct 02); 13:e89213

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Woman uses a wearable health monitor while a man reviews data on a tablet.

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A Digital System to Assess Mental Health in People With Intellectual Disability (MENTALSED): Protocol for a Development and Pilot Study

Jairo Rodríguez-Medina, Clara Gonzalez Sanguino, Elena Betegón, Alba Ayuso-Lanchares, Teresa Boemo

JMIR Res Protoc 2026 (Sep 30); 15:e106072

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Elderly woman in white blouse using a tablet computer with a dessert on the side

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Smartphone-Based Passive Sensing of Activity Levels and Behavioral Activation During Psychosocial Interventions for Older Adults With Depression: Longitudinal Observational Study

Soohyun Kim, Oded Bein, Emily Carter, Hongzhe Zhang, Jihui L Diaz, Zilong Yu, Patricia Marino, Jo Anne Sirey, Dimitris Kiosses, George Alexopoulos, Nili Solomonov, Samprit Banerjee

J Med Internet Res 2026 (Sep 30); 28:e92348

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Woman in a coat looking up while holding a smartphone outdoors in autumn

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Incremental Value of Smartphone Sensing for Monitoring Momentary Affect Intensity in Adults Using Transformer-Based Models: Observational Study

Yiqin Zhu, Yuyi Yang, Renee J Thompson

JMIR Mhealth Uhealth 2026 (Sep 28); 14:e90970

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Person using a mental health app in a hospital room, selecting a happy emoji.

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Monitoring Within-Person Dynamics in Adolescents Hospitalized for Acute Suicidal Distress: Protocol for an Intensive Longitudinal Study

Laura Nigro, Konstantin Drexl, Alberto Forte, Carole Kapp, Kerstin Jessica Plessen, Romain Gallien, Laurent Michaud, Marco Armando, Maude Schneider

JMIR Res Protoc 2026 (Sep 25); 15:e93016

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Plus-size woman walking on a park path with mountains in the background

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Using Momentary Measures to Understand Physical Activity Adoption and Maintenance: Protocol for a Longitudinal Study

Neng Wan, Wonwoo Byun, Ming Wen, Emre Ertin, Jeff Phillips, Nia Aitaoto, Simon Brewer, David W Wetter

JMIR Res Protoc 2026 (Sep 25); 15:e108686

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Doctor pointing to tablet with patient questionnaire during medical consultation

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Longitudinal Digital Phenotyping of Traditional Chinese Medicine Constitution From Routine Health Examination Records: Retrospective Clinical Informatics Study

Yuzhi Huo, Gao Deng, Li Kang, Haizhi Qin, Li Xiao, Ying Deng, Xin Chen, Dan Ding, Fei Wang, Mei Zhang, Min Chen

JMIR Med Inform 2026 (Sep 23); 14:e100063

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Man using a smart ring and phone for health tracking

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Wearable-Based Assessment for Relapse Prediction Following Repetitive Transcranial Magnetic Stimulation for Depression: Protocol for a Feasibility Study (WARN-D Study)

Caroline Wanderley Espinola, Clarissa Dine, Zakariya Rekkas, Benicio N Frey, Sridhar Krishnan, Dante Duarte, Fabiano A Gomes, Michael S B Mak

JMIR Res Protoc 2026 (Sep 21); 15:e89466

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Doctor reviews sleep study report on tablet with patient

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Clinical Implementation of Wearable-Derived Sleep and Activity Reporting for Inpatient Psychiatric Monitoring

Brien William Culhane, Habiballah Rahimi-Eichi, Robert Dennis Patterson, Agustin Go Yip, Kayla Huesman, Kristin Kostick-Quenet, Joshua Salvi, Philippe Beauchamp, Kerry James Ressler, Justin Taylor Baker

JMIR Form Res 2026 (Sep 21); 10:e88466

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Grilled chicken breast with a fresh garden salad, kidney beans, and almonds on a white plate.

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Effects of a Nutritionally Balanced Between-Meal Food Product on Brain Function in Older Adults: Protocol for a Randomized Controlled Trial (the MiniMeal Study)

Lina Tingö, Jort Veen, Pernilla Andersson, Myrto Chatzopoulou, Julia Rode, Kristina Andersson, Işılay Kaya, Ana Rascón, Peter Edholm, Robert Brummer, Cecilia Bergh, Ashley N Hutchinson

JMIR Res Protoc 2026 (Sep 17); 15:e94648

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Diverse people connecting through technology and nature in a vibrant city

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Digital Phenotyping of Lifestyle Profiles and Mental Well-Being in German Adults: Prospective Longitudinal Cohort Study

Ningzhe Zhu, Ramona Schoedel, Larissa Sust, Markus Bühner, Yannik Terhorst

J Med Internet Res 2026 (Sep 14); 28:e101850

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Child with headphones lying in bed, looking at a smartphone

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The Preliminary Efficacy and Feasibility of SMILE Serious Game for Adolescents and Young Adults: Protocol for Cluster Randomized Multisite Adaptive Trial Design

Ewelina Smoktunowicz, Jan Maciejewski, Magdalena Lesnierowska, Magdalena Pietrzak, Franziska Großwendt, Gwendolyn Mayer, Jobst-Hendrik Schultz, Nelli Tschobur, Mel McKendrick, Helen Stocks, Francesca Floris, Dina Guglielmi, Zouhair Haddi, Carlo Mazzola, Izidor Mlakar, Urška Smrke, Laura Fernández García, Esther Parra Vidales, Elisa Sáez Muñoz, Sebastian Bruchhaus, Matthias Hemmje, Dominic Heutelbeck, Dah Diarra, Habib Nasser, Alex Butean, Marco Polak, Panagiota Mourettou, Angelos Parmatzias, Ula Kolinska, Matthias Schwannauer

JMIR Res Protoc 2026 (Sep 03); 15:e96292

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Woman sleeping with a CPAP mask for sleep apnea treatment

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Characteristics of Abdominal Movement Signals Measured by a Wireless Abdomen-Worn Sensor During Home Sleep Apnea Testing: Pilot Observational Study

Thi Hang Dang, Nam-Hwan Sung, Hyung-ki Min, Seongmun Kim, Heein Yoon, Franklin Bien

JMIR Form Res 2026 (Sep 01); 10:e93351

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Woman with dreadlocks checking her smartwatch outdoors in winter

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The Representation of Different Populations in Studies Assessing the Validity of Consumer Wearable Photoplethysmography-Based Measurements: Scoping Review

Rebecca M Schipper, Fatime Oumar Djibrillah, Meyke Roosink, Laura Winkens, Arlene John, Eric Hazebroek, Annemieke Witteveen, Agnes A M Berendsen

JMIR Mhealth Uhealth 2026 (Aug 28); 14:e87324

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Two men examine a smartwatch displaying health metrics.

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A One-Year Study Using Digital Biomarkers From Sensing Technologies to Assess Changes in Physical Activity Levels and Sleep Quality in Nursing Home Residents With Dementia: Observational Study

Lydia D Boyle, Monica Patrascu, Bettina S Husebo, Kristoffer Haugarvoll, Ole Martin Steihaug, Brice Marty

JMIR Nursing 2026 (Aug 28); 9:e95194

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Medical team performs echocardiogram on patient to view heart

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Operationalizing AI-Enabled Cardiovascular Biomarkers: A Clinician-Centered Framework for Validation, Governance, and Workflow Integration

Dabeluchi Chiedozie Ngwu

JMIR Cardio 2026 (Aug 28); 10:e103401

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Surgeon interacting with futuristic medical displays of brain, heart, and DNA

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Digital Phenotyping in Health Research: Scoping Review of Methods, Gaps, and Opportunities

Nolwenn Badier, Alice Lafitte, Audrey Difernand, Gloria A Aguayo, Guy Fagherazzi, Jukka-Pekka Onnela, Benjamin Vittrant, Bastien Lechat, Quentin De Larochelambert, Jean-François Toussaint, Lidia Delrieu

J Med Internet Res 2026 (Aug 27); 28:e91747

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Woman using smartphone, digital brain with heart, mental wellness

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Individual-Level Modeling of Depressive Symptom Severity Using Smartphone and Wearable Data: Time-Aware 1-Year Study With Feature-Group Contributions

Simon Schreynemackers, Johannes Leimhofer, Milica Petrovic, Hanna Reich, Sascha Ludwig, Andreas Dominik, Dominik Heider, Ulrich Hegerl, the MONDY Consortium

JMIR Form Res 2026 (Aug 25); 10:e99204

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Woman's brain and nervous system with network connections, symbolizing cognition

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