Published on in Vol 6, No 11 (2018): November

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/12106, first published .
An Empathy-Driven, Conversational Artificial Intelligence Agent (Wysa) for Digital Mental Well-Being: Real-World Data Evaluation Mixed-Methods Study

An Empathy-Driven, Conversational Artificial Intelligence Agent (Wysa) for Digital Mental Well-Being: Real-World Data Evaluation Mixed-Methods Study

An Empathy-Driven, Conversational Artificial Intelligence Agent (Wysa) for Digital Mental Well-Being: Real-World Data Evaluation Mixed-Methods Study

Journals

  1. Abd-Alrazaq A, Safi Z, Alajlani M, Warren J, Househ M, Denecke K. Technical Metrics Used to Evaluate Health Care Chatbots: Scoping Review. Journal of Medical Internet Research 2020;22(6):e18301 View
  2. Abd-Alrazaq A, Rababeh A, Alajlani M, Bewick B, Househ M. Effectiveness and Safety of Using Chatbots to Improve Mental Health: Systematic Review and Meta-Analysis. Journal of Medical Internet Research 2020;22(7):e16021 View
  3. Park S, Choi J, Lee S, Oh C, Kim C, La S, Lee J, Suh B. Designing a Chatbot for a Brief Motivational Interview on Stress Management: Qualitative Case Study. Journal of Medical Internet Research 2019;21(4):e12231 View
  4. Gaffney H, Mansell W, Tai S. Agents of change: Understanding the therapeutic processes associated with the helpfulness of therapy for mental health problems with relational agent MYLO. DIGITAL HEALTH 2020;6:205520762091158 View
  5. Numanee I, Zafar N, Karim A, Ismail S. Developing empathy among first-year university undergraduates through English language course: A phenomenological study. Heliyon 2020;6(6):e04021 View
  6. Abd-Alrazaq A, Alajlani M, Ali N, Denecke K, Bewick B, Househ M. Perceptions and Opinions of Patients About Mental Health Chatbots: Scoping Review. Journal of Medical Internet Research 2021;23(1):e17828 View
  7. Kretzschmar K, Tyroll H, Pavarini G, Manzini A, Singh I. Can Your Phone Be Your Therapist? Young People’s Ethical Perspectives on the Use of Fully Automated Conversational Agents (Chatbots) in Mental Health Support. Biomedical Informatics Insights 2019;11:117822261982908 View
  8. Oh J, Jang S, Kim H, Kim J. Efficacy of mobile app-based interactive cognitive behavioral therapy using a chatbot for panic disorder. International Journal of Medical Informatics 2020;140:104171 View
  9. D’Alfonso S. AI in mental health. Current Opinion in Psychology 2020;36:112 View
  10. Fiske A, Henningsen P, Buyx A. Your Robot Therapist Will See You Now: Ethical Implications of Embodied Artificial Intelligence in Psychiatry, Psychology, and Psychotherapy. Journal of Medical Internet Research 2019;21(5):e13216 View
  11. Hauser-Ulrich S, Künzli H, Meier-Peterhans D, Kowatsch T. A Smartphone-Based Health Care Chatbot to Promote Self-Management of Chronic Pain (SELMA): Pilot Randomized Controlled Trial. JMIR mHealth and uHealth 2020;8(4):e15806 View
  12. Gaffney H, Mansell W, Tai S. Conversational Agents in the Treatment of Mental Health Problems: Mixed-Method Systematic Review. JMIR Mental Health 2019;6(10):e14166 View
  13. Kocaballi A, Berkovsky S, Quiroz J, Laranjo L, Tong H, Rezazadegan D, Briatore A, Coiera E. The Personalization of Conversational Agents in Health Care: Systematic Review. Journal of Medical Internet Research 2019;21(11):e15360 View
  14. Tudor Car L, Dhinagaran D, Kyaw B, Kowatsch T, Joty S, Theng Y, Atun R. Conversational Agents in Health Care: Scoping Review and Conceptual Analysis. Journal of Medical Internet Research 2020;22(8):e17158 View
  15. Abd-alrazaq A, Alajlani M, Alalwan A, Bewick B, Gardner P, Househ M. An overview of the features of chatbots in mental health: A scoping review. International Journal of Medical Informatics 2019;132:103978 View
  16. Palanica A, Flaschner P, Thommandram A, Li M, Fossat Y. Physicians’ Perceptions of Chatbots in Health Care: Cross-Sectional Web-Based Survey. Journal of Medical Internet Research 2019;21(4):e12887 View
  17. Schlage J, Perich T. Mental health mobile application usage in young adults with a family history of mental illness. Australian Psychologist 2020;55(6):660 View
  18. Yüzbaşıoğlu E. Attitudes and perceptions of dental students towards artificial intelligence. Journal of Dental Education 2021;85(1):60 View
  19. Oh S, Kim J, Choi S, Lee H, Hong J, Kwon S. Physician Confidence in Artificial Intelligence: An Online Mobile Survey. Journal of Medical Internet Research 2019;21(3):e12422 View
  20. Sarda A, Munuswamy S, Sarda S, Subramanian V. Using Passive Smartphone Sensing for Improved Risk Stratification of Patients With Depression and Diabetes: Cross-Sectional Observational Study. JMIR mHealth and uHealth 2019;7(1):e11041 View
  21. Aafjes-van Doorn K, Kamsteeg C, Bate J, Aafjes M. A scoping review of machine learning in psychotherapy research. Psychotherapy Research 2021;31(1):92 View
  22. Moore J, Caudill R. The Bot Will See You Now. Psychiatric Clinics of North America 2019;42(4):627 View
  23. Chew A, Ong R, Lei H, Rajendram M, K V G, Verma S, Fung D, Leong J, Gunasekeran D. Digital Health Solutions for Mental Health Disorders During COVID-19. Frontiers in Psychiatry 2020;11 View
  24. Qu C, Sas C, Daudén Roquet C, Doherty G. Functionality of Top-Rated Mobile Apps for Depression: Systematic Search and Evaluation. JMIR Mental Health 2020;7(1):e15321 View
  25. Dosovitsky G, Pineda B, Jacobson N, Chang C, Escoredo M, Bunge E. Artificial Intelligence Chatbot for Depression: Descriptive Study of Usage. JMIR Formative Research 2020;4(11):e17065 View
  26. Chung K, Cho H, Park J. A Chatbot for Perinatal Women’s and Partners’ Obstetric and Mental Health Care: Development and Usability Evaluation Study. JMIR Medical Informatics 2021;9(3):e18607 View
  27. Vasudevan M, Alagarsamy S, Mehrolia S, Jeevananda S. Can bot be my mental health therapist? – A pandemic panorama. Journal of Psychiatric Research 2021;134:30 View
  28. Xu B, Zhuang Z. Survey on psychotherapy chatbots. Concurrency and Computation: Practice and Experience 2020 View
  29. Mehdi M, Dode A, Pryss R, Schlee W, Reichert M, Hauck F. Contemporary Review of Smartphone Apps for Tinnitus Management and Treatment. Brain Sciences 2020;10(11):867 View
  30. Vaidyam A, Linggonegoro D, Torous J. Changes to the Psychiatric Chatbot Landscape: A Systematic Review of Conversational Agents in Serious Mental Illness: Changements du paysage psychiatrique des chatbots: une revue systématique des agents conversationnels dans la maladie mentale sérieuse. The Canadian Journal of Psychiatry 2021;66(4):339 View
  31. Schultchen D, Terhorst Y, Holderied T, Stach M, Messner E, Baumeister H, Sander L. Stay Present with Your Phone: A Systematic Review and Standardized Rating of Mindfulness Apps in European App Stores. International Journal of Behavioral Medicine 2020 View
  32. Safi Z, Abd-Alrazaq A, Khalifa M, Househ M. Technical Aspects of Developing Chatbots for Medical Applications: Scoping Review. Journal of Medical Internet Research 2020;22(12):e19127 View
  33. Laacke S, Mueller R, Schomerus G, Salloch S. Artificial Intelligence, Social Media and Depression. A New Concept of Health-Related Digital Autonomy. The American Journal of Bioethics 2021;21(7):4 View
  34. Ilan Y. Second-Generation Digital Health Platforms: Placing the Patient at the Center and Focusing on Clinical Outcomes. Frontiers in Digital Health 2020;2 View
  35. Khilji A, Manna R, Laskar S, Pakray P, Das D, Bandyopadhyay S, Gelbukh A. CookingQA: Answering Questions and Recommending Recipes Based on Ingredients. Arabian Journal for Science and Engineering 2021;46(4):3701 View
  36. Daley K, Hungerbuehler I, Cavanagh K, Claro H, Swinton P, Kapps M. Preliminary Evaluation of the Engagement and Effectiveness of a Mental Health Chatbot. Frontiers in Digital Health 2020;2 View
  37. Shuaib A, Arian H, Shuaib A. <p>The Increasing Role of Artificial Intelligence in Health Care: Will Robots Replace Doctors in the Future?</p>. International Journal of General Medicine 2020;Volume 13:891 View
  38. Unger J, Morales I, De Paepe P, Roland M. Neo-Hippocratic healthcare policies: professional or industrial healthcare delivery? A choice for doctors, patients, and their organisations. BMC Health Services Research 2020;20(S2) View
  39. Milne-Ives M, de Cock C, Lim E, Shehadeh M, de Pennington N, Mole G, Normando E, Meinert E. The Effectiveness of Artificial Intelligence Conversational Agents in Health Care: Systematic Review. Journal of Medical Internet Research 2020;22(10):e20346 View
  40. Pacheco-Lorenzo M, Valladares-Rodríguez S, Anido-Rifón L, Fernández-Iglesias M. Smart conversational agents for the detection of neuropsychiatric disorders: A systematic review. Journal of Biomedical Informatics 2021;113:103632 View
  41. Li X, Zhou P, Wu J, Shanthini A, Vadivel T. Research on artificial intelligence learning system based on psychological knowledge to adjust anxiety and depression. Behaviour & Information Technology 2020:1 View
  42. Martiniello N, Asuncion J, Fichten C, Jorgensen M, Havel A, Harvison M, Legault A, Lussier A, Vo C. Artificial intelligence for students in postsecondary education. AI Matters 2020;6(3):17 View
  43. Wu A, Scult M, Barnes E, Betancourt J, Falk A, Gunning F. Smartphone apps for depression and anxiety: a systematic review and meta-analysis of techniques to increase engagement. npj Digital Medicine 2021;4(1) View
  44. Söderström A, Shatte A, Fuller-Tyszkiewicz M. Can intelligent agents improve data quality in online questiosnnaires? A pilot study. Behavior Research Methods 2021 View
  45. Jang S, Kim J, Kim S, Hong J, Kim S, Kim E. Mobile app-based chatbot to deliver cognitive behavioral therapy and psychoeducation for adults with attention deficit: A development and feasibility/usability study. International Journal of Medical Informatics 2021;150:104440 View
  46. Planas R, Yuguero O. Technological prescription: evaluation of the effectiveness of mobile applications to improve depression and anxiety. Systematic review. Informatics for Health and Social Care 2021;46(3):273 View
  47. Martinengo L, Stona A, Griva K, Dazzan P, Pariante C, von Wangenheim F, Car J. Self-guided Cognitive Behavioral Therapy Apps for Depression: Systematic Assessment of Features, Functionality, and Congruence With Evidence. Journal of Medical Internet Research 2021;23(7):e27619 View
  48. Gabrielli S, Rizzi S, Bassi G, Carbone S, Maimone R, Marchesoni M, Forti S. Engagement and Effectiveness of a Healthy-Coping Intervention via Chatbot for University Students During the COVID-19 Pandemic: Mixed Methods Proof-of-Concept Study. JMIR mHealth and uHealth 2021;9(5):e27965 View
  49. Delanerolle G, Yang X, Shetty S, Raymont V, Shetty A, Phiri P, Hapangama D, Tempest N, Majumder K, Shi J. Artificial intelligence: A rapid case for advancement in the personalization of Gynaecology/Obstetric and Mental Health care. Women's Health 2021;17:174550652110181 View
  50. Kolenik T, Gams M. Intelligent Cognitive Assistants for Attitude and Behavior Change Support in Mental Health: State-of-the-Art Technical Review. Electronics 2021;10(11):1250 View
  51. Martinengo L, Lo N, Goh W, Tudor Car L. Choice of Behavioral Change Techniques in Health Care Conversational Agents: Protocol for a Scoping Review. JMIR Research Protocols 2021;10(7):e30166 View
  52. Beilharz F, Sukunesan S, Rossell S, Kulkarni J, Sharp G. Development of a Positive Body Image Chatbot (KIT) With Young People and Parents/Carers: Qualitative Focus Group Study. Journal of Medical Internet Research 2021;23(6):e27807 View
  53. Mehta A, Niles A, Vargas J, Marafon T, Couto D, Gross J. Acceptability and Effectiveness of Artificial Intelligence Therapy for Anxiety and Depression (Youper): Longitudinal Observational Study. Journal of Medical Internet Research 2021;23(6):e26771 View
  54. Mlakar I, Šafran V, Hari D, Rojc M, Alankuş G, Pérez Luna R, Ariöz U. Multilingual Conversational Systems to Drive the Collection of Patient-Reported Outcomes and Integration into Clinical Workflows. Symmetry 2021;13(7):1187 View
  55. Lin A, Espay A. Remote delivery of cognitive behavioral therapy to patients with functional neurological disorders: Promise and challenges. Epilepsy & Behavior Reports 2021;16:100469 View
  56. Kazzazi F. The automation of doctors and machines: A classification for AI in medicine (ADAM framework). Future Healthcare Journal 2021;8(2):e257 View
  57. Villatoro-Tello E, Parida S, Kumar S, Motlicek P. Applying Attention-Based Models for Detecting Cognitive Processes and Mental Health Conditions. Cognitive Computation 2021 View
  58. Mulgund P, Sharman R, Rifkin D, Marrazzo S. Design, Development, and Evaluation of a Telemedicine Platform for Patients With Sleep Apnea (Ognomy): Design Science Research Approach. JMIR Formative Research 2021;5(7):e26059 View
  59. Teepe G, Da Fonseca A, Kleim B, Jacobson N, Salamanca Sanabria A, Tudor Car L, Fleisch E, Kowatsch T. Just-in-time Adaptive Mechanisms of Popular Mobile Applications for Individuals with Depression: Systematic Review (Preprint). Journal of Medical Internet Research 2021 View
  60. Mauriello M, Tantivasadakarn N, Mora-Mendoza M, Lincoln E, Hon G, Nowruzi P, Simon D, Hansen L, Goenawan N, Kim J, Gowda N, Jurafsky D, Paredes P. Popbots—A Suite of Mobile Conversational Agents for Daily Stress Management: A Mixed Methods Exploratory Study (Preprint). JMIR Formative Research 2020 View
  61. Vilaza G, McCashin D. Is the Automation of Digital Mental Health Ethical? Applying an Ethical Framework to Chatbots for Cognitive Behaviour Therapy. Frontiers in Digital Health 2021;3 View
  62. Nwaogu J, Chan A, Naslund J, Hon C, Belonwu C, YANG J. Exploring the Barriers and Motivators for Using Digital Mental Health Interventions Among Construction Personnel in Nigeria: Qualitative Study (Preprint). JMIR Formative Research 2020 View
  63. Klos M, Escoredo M, Joerin A, Lemos V, Rauws M, Bunge E. Artificial Intelligence–Based Chatbot for Anxiety and Depression in University Students: Pilot Randomized Controlled Trial. JMIR Formative Research 2021;5(8):e20678 View

Books/Policy Documents

  1. McAllister P, Kerr J, McTear M, Mulvenna M, Bond R, Kirby K, Morning J, Glover D. Chatbot Research and Design. View
  2. Fiske A, Henningsen P, Buyx A. Ethics of Digital Well-Being. View
  3. Luxton D, Sirotin A. Innovations in Global Mental Health. View
  4. Cho P, Singh K, Dunn J. Artificial Intelligence in Medicine. View
  5. van Wezel M, Croes E, Antheunis M. Chatbot Research and Design. View
  6. Benítez-Guijarro A, Bond R, Booth F, Callejas Z, Ennis E, Esposito A, Kraus M, McConvey G, McTear M, Mulvenna M, Potts C, Pragst L, Turkington R, Wagner N, Zheng H. Conversational Dialogue Systems for the Next Decade. View
  7. Callejas Z, Griol D. Dialog Systems. View
  8. Galindo M, Moreno L. Graph Structures for Knowledge Representation and Reasoning. View
  9. Kara O, Kurutkan M. The Impact of Artificial Intelligence on Governance, Economics and Finance, Volume I. View
  10. Jovanović M, Jevremović A, Pejović-Milovančević M. Artificial Intelligence: Theory and Applications. View
  11. McKay G. Shame 4.0. View
  12. Davids J, Ashrafian H. Artificial Intelligence in Medicine. View
  13. Denecke K, Abd-Alrazaq A, Househ M. Multiple Perspectives on Artificial Intelligence in Healthcare. View