Tracking and Monitoring Mood Stability of Patients With Major Depressive Disorder by Machine Learning Models Using Passive Digital Data: Prospective Naturalistic Multicenter Study

Ran Bai   ^{1, 2 *} , MS ;   Le Xiao   ^{3 *} , PhD, MD ;   Yu Guo   ⁴ , MEng ;   Xuequan Zhu   ³ , MA ;   Nanxi Li   ³ , MD ;   Yashen Wang   ² , PhD ;   Qinqin Chen   ² , PhD ;   Lei Feng   ³ , PhD, MD ;   Yinghua Wang   ² , PhD ;   Xiangyi Yu   ² , MS ;   Chunxue Wang   ⁵ , MD, PhD ;   Yongdong Hu   ⁶ , MD, PhD ;   Zhandong Liu   ⁷ , MD ;   Haiyong Xie   ^{1, 2} , PhD ;   Gang Wang   ^{1, 3} , PhD, MD

¹ Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China

² National Engineering Laboratory for Risk Perception and Prevention, Beijing, China

³ The National Clinical Research Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China

⁴ Beijing University of Posts and Telecommunications, Beijing, China

⁵ Department of Neuropsychiatry and Clinical Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

⁶ Department of Psychological Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

⁷ Department of Neurology, Medical Health Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China

*these authors contributed equally