Wearable Data From Subjects Playing Super Mario, Taking University Exams, or Performing Physical Exercise Help Detect Acute Mood Disorder Episodes via Self-Supervised Learning: Prospective, Exploratory, Observational Study

Filippo Corponi   ¹ , MSc, MD ;   Bryan M Li   ^{1, 2} , MSc ;   Gerard Anmella   ^{3, 4, 5, 6} , MD, PhD ;   Clàudia Valenzuela-Pascual   ^{3, 4, 5, 6} , MSc ;   Ariadna Mas   ^{3, 4, 5, 6} , MSc ;   Isabella Pacchiarotti   ^{3, 4, 5, 6} , MD, PhD ;   Marc Valentí   ^{3, 4, 5, 6} , MD, PhD ;   Iria Grande   ^{3, 4, 5, 6} , MD, PhD ;   Antoni Benabarre   ^{3, 4, 5, 6} , MD, PhD ;   Marina Garriga   ^{3, 4, 5, 6} , MD, PhD ;   Eduard Vieta   ^{3, 4, 5, 6} , MD, PhD ;   Allan H Young   ⁷ , MD, PhD ;   Stephen M Lawrie   ⁸ , MD ;   Heather C Whalley   ^{8, 9} , PhD ;   Diego Hidalgo-Mazzei   ^{3, 4, 5, 6, 7 *} , MD, PhD ;   Antonio Vergari   ^{1 *} , PhD

¹ School of Informatics, University of Edinburgh, Edinburgh, United Kingdom

² The Alan Turing Institute, London, United Kingdom

³ Bipolar and Depressive Disorders Unit, Department of Psychiatry and Psychology, Hospital Clínic de Barcelona, Barcelona, Spain

⁴ Institut d’Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain

⁵ Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, Madrid, Spain

⁶ Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, Barcelona, Spain

⁷ Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom

⁸ Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom

⁹ Generation Scotland, Institute for Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom

*these authors contributed equally